Historische Wurzeln der Entkirchlichung in der DDR

"Das Gebiet der ehemaligen DDR ist eine der am meisten säkularisierten Regionen Europas. Der bekannte Kirchensoziologe E. Neubert spricht drastisch von einem 'religiösen Super-GAU'. Eine weitverbreitete These lautet, die großräumige Entkirchlichung und religiöse Desozialisation sei eine unmittelbare Auswirkung der SED-Diktatur. Dieser Annahme zufolge müßte die Entkirchlichung nicht als gleitender Prozeß der langen Dauer, sondern als ein kurzfristiger religiös-kultureller Blackout begriffen werden. Die große Selbstverständlichkeit dieser Annahme fordert zu ihrer Überprüfung auf. Aus historischer Perspektive ist nach den Traditionen des Atheismus in Mitteldeutschland zu fragen. Atheistische Kulturinseln konnten vor und nach 1918 in eine weithin noch kirchlich dominierte Landschaft eingebettet sein. Die Ziffern der Kirchenstatistik liefern nur unzureichende Indikatoren für religiöse Verhältnisse und weltanschauliche Orientierungen. Der Blick auf die zwanziger Jahre und die Zeit des Dritten Reiches kann helfen, den Entkirchlichungsprozeß in der ehemaligen DDR differenzierter zu erfassen." (Autorenreferat

Topology of the gauge-invariant gauge field in two-color QCD

We investigate solutions to a nonlinear integral equation which has a central role in implementing the non-Abelian Gauss's Law and in constructing gauge-invariant quark and gluon fields. Here we concern ourselves with solutions to this same equation that are not operator-valued, but are functions of spatial variables and carry spatial and SU(2) indices. We obtain an expression for the gauge-invariant gauge field in two-color QCD, define an index that we will refer to as the ``winding number'' that characterizes it, and show that this winding number is invariant to a small gauge transformation of the gauge field on which our construction of the gauge-invariant gauge field is based. We discuss the role of this gauge field in determining the winding number of the gauge-invariant gauge field. We also show that when the winding number of the gauge field is an integer $\ell{\neq}0$, the gauge-invariant gauge field manifests winding numbers that are not integers, and are half-integers only when $\ell=0$.Comment: 26 pages including 6 encapsulated postscript figures. Numerical errors have been correcte

Investigating the association between occupational exposure to asbestos and ovarian carcinoma: results from a pilot study in Germany

Background The aim of this pilot study was to assess the feasibility of a large-scale epidemiologic investigation elucidating the quantitative association between occupational exposure to asbestos and ovarian cancer in former German asbestos workers. Methods Between December 2017 and May 2018, a random sample of one thousand insured woman registered at the health service of a German trade association as formerly occupationally exposed to asbestos were invited to participate in a pilot study. Participation included a phone interview using a standardised questionnaire. The feasibility of the project was evaluated using a priori defined criteria. They included response, number of cases, eligibility of the questionnaire data for exact estimation of asbestos fibre-years, and availability of relevant medical documentation (imaging procedures, medical reports, and histologic materials). Results The response (17%) was clearly below the intended number of 60%. With six tumour suspects, of which two could be confirmed by medical documents, the number of cases was within the expected range of two to eleven cases. Exact asbestos fibre-year estimations could be performed for 29% of all interviewees, but only for one suspected case. Medical documentation could be collected for only few participants, while no histology reports could be obtained for all cases. Thus, only the feasibility criterion of the expected number of cases was fulfilled. Conclusion The results of the pilot study indicate that the planned project is feasible only to a very limited extent. For further planning of the study, measures to improve recruitment of participants are necessary

Experimental Validation of a Faithful Binary Circuit Model

International audienceFast digital timing simulations based on continuous-time, digital-value circuit models are an attractive and heavily used alternative to analog simulations. Models based on analytic delay formulas are particularly interesting here, as they also facilitate formal verification and delay bound synthesis of complex circuits. Recently, Függer et al. (arXiv:1406.2544 [cs.OH]) proposed a circuit model based on so-called involution channels. It is the first binary circuit model that realistically captures solvability of short-pulse filtration, a non-trivial glitch propagation problem related to building one-shot inertial delays. In this work, we address the question of whether involu-tion channels also accurately model the delay of real circuits. Using both Spice simulations and physical measurements, we confirm that modeling an inverter chain by involution channels accurately describes reality. We also demonstrate that transitions in vanishing pulse trains are accurately predicted by the involution model. For our Spice simulations, we used both UMC-90 and UMC-65 technology, with varying supply voltages from nominal down to near sub-threshold range. The measurements were performed on a special-purpose UMC-90 ASIC that combines an inverter chain with low-intrusive high-speed on-chip analog amplifiers

The Long-Baseline Neutrino Experiment: Exploring Fundamental Symmetries of the Universe

The preponderance of matter over antimatter in the early Universe, the dynamics of the supernova bursts that produced the heavy elements necessary for life and whether protons eventually decay --- these mysteries at the forefront of particle physics and astrophysics are key to understanding the early evolution of our Universe, its current state and its eventual fate. The Long-Baseline Neutrino Experiment (LBNE) represents an extensively developed plan for a world-class experiment dedicated to addressing these questions. LBNE is conceived around three central components: (1) a new, high-intensity neutrino source generated from a megawatt-class proton accelerator at Fermi National Accelerator Laboratory, (2) a near neutrino detector just downstream of the source, and (3) a massive liquid argon time-projection chamber deployed as a far detector deep underground at the Sanford Underground Research Facility. This facility, located at the site of the former Homestake Mine in Lead, South Dakota, is approximately 1,300 km from the neutrino source at Fermilab -- a distance (baseline) that delivers optimal sensitivity to neutrino charge-parity symmetry violation and mass ordering effects. This ambitious yet cost-effective design incorporates scalability and flexibility and can accommodate a variety of upgrades and contributions. With its exceptional combination of experimental configuration, technical capabilities, and potential for transformative discoveries, LBNE promises to be a vital facility for the field of particle physics worldwide, providing physicists from around the globe with opportunities to collaborate in a twenty to thirty year program of exciting science. In this document we provide a comprehensive overview of LBNE's scientific objectives, its place in the landscape of neutrino physics worldwide, the technologies it will incorporate and the capabilities it will possess.Comment: Major update of previous version. This is the reference document for LBNE science program and current status. Chapters 1, 3, and 9 provide a comprehensive overview of LBNE's scientific objectives, its place in the landscape of neutrino physics worldwide, the technologies it will incorporate and the capabilities it will possess. 288 pages, 116 figure

Vascular endothelial growth factor-A165b prevents diabetic neuropathic pain and sensory neuronal degeneration

Diabetic peripheral neuropathy affects up to half of diabetic patients. This neuronal damage leads to sensory disturbances, including allodynia and hyperalgesia. Many growth factors have been suggested as useful treatments for prevention of neurodegeneration, including the vascular endothelial growth factor (VEGF) family. VEGF-A is generated as two alternative splice variant families. The most widely studied isoform, VEGF-A165a is both pro-angiogenic and neuroprotective, but pro-nociceptive and increases vascular permeability in animal models. Streptozotocin (STZ)-induced diabetic rats develop both hyperglycaemia and many of the resulting diabetic complications seen in patients, including peripheral neuropathy. In the present study, we show that the anti-angiogenic VEGF-A splice variant, VEGF-A165b, is also a potential therapeutic for diabetic neuropathy. Seven weeks of VEGF-A165b treatment in diabetic rats reversed enhanced pain behaviour in multiple behavioural paradigms and was neuroprotective, reducing hyperglycaemia-induced activated caspase 3 (AC3) levels in sensory neuronal subsets, epidermal sensory nerve fibre loss and aberrant sciatic nerve morphology. Furthermore, VEGF-A165b inhibited a STZ-induced increase in Evans Blue extravasation in dorsal root ganglia (DRG), saphenous nerve and plantar skin of the hind paw. Increased transient receptor potential ankyrin 1 (TRPA1) channel activity is associated with the onset of diabetic neuropathy. VEGF-A165b also prevented hyperglycaemia-enhanced TRPA1 activity in an in vitro sensory neuronal cell line indicating a novel direct neuronal mechanism that could underlie the anti-nociceptive effect observed in vivo. These results demonstrate that in a model of Type I diabetes VEGF-A165b attenuates altered pain behaviour and prevents neuronal stress, possibly through an effect on TRPA1 activity

Measurements of branching fraction ratios and CP-asymmetries in suppressed B^- -> D(-> K^+ pi^-)K^- and B^- -> D(-> K^+ pi^-)pi^- decays

We report the first reconstruction in hadron collisions of the suppressed decays B^- -> D(-> K^+ pi^-)K^- and B^- -> D(-> K^+ pi^-)pi^-, sensitive to the CKM phase gamma, using data from 7 fb^-1 of integrated luminosity collected by the CDF II detector at the Tevatron collider. We reconstruct a signal for the B^- -> D(-> K^+ pi^-)K^- suppressed mode with a significance of 3.2 standard deviations, and measure the ratios of the suppressed to favored branching fractions R(K) = [22.0 \pm 8.6(stat)\pm 2.6(syst)]\times 10^-3, R^+(K) = [42.6\pm 13.7(stat)\pm 2.8(syst)]\times 10^-3, R^-(K)= [3.8\pm 10.3(stat)\pm 2.7(syst]\times 10^-3, as well as the direct CP-violating asymmetry A(K) = -0.82\pm 0.44(stat)\pm 0.09(syst) of this mode. Corresponding quantities for B^- -> D(-> K^+ pi^-)pi^- decay are also reported.Comment: 8 pages, 1 figure, accepted by Phys.Rev.D Rapid Communications for Publicatio