Novel mid-infrared dispersive wave generation in gas-filled PCF by transient ionization-driven changes in dispersion

Gas-filled hollow-core photonic crystal fibre (PCF) is being used to generate ever wider supercontinuum spectra, in particular via dispersive wave (DW) emission in the deep and vacuum ultraviolet, with a multitude of applications. DWs are the result of the resonant transfer of energy from a self-compressed soliton, a process which relies crucially on phase matching. It was recently predicted that, in the strong-field regime, the additional transient anomalous dispersion introduced by gas ionization would allow phase-matched DW generation in the mid-infrared (MIR)-something that is forbidden in the absence of free electrons. Here we report for the first time the experimental observation of such MIR DWs, embedded in a 4.7-octave-wide supercontinuum that uniquely reaches simultaneously to the vacuum ultraviolet, with up to 1.7 W of total average power

Bird mortality related to collisions with ski–lift cables: do we estimate just the tip of the iceberg?

Collisions with ski–lift cables are an important cause of death for grouse species living close to alpine ski resorts. As several biases may reduce the detection probability of bird carcasses, the mortality rates related to these collisions are generally underestimated. The possibility that injured birds may continue flying for some distance after striking cables represents a major source of error, known as crippling bias. Estimating the crippling losses resulting from birds dying far from the ski–lift corridors is difficult and it is usually assessed by systematic searches of carcasses on both sides of the ski–lifts. Using molecular tracking, we were able to demonstrate that a rock ptarmigan hen flew up to 600 m after striking a ski–lift cable, a distance preventing its detection by traditional carcasses surveys. Given the difficulty in conducting systematic searches over large areas surrounding the ski–lifts, only an experiment using radio–tagged birds would allow us to estimate the real mortality rate associated with cable collision

Design and implementation of an ultrasonic sensor for rapid monitoring of industrial malolactic fermentation of wines

Ultrasound is an emerging technology that can be applied to monitor food processes. However, ultrasonic techniques are usually limited to research activities within a laboratory environment and they are not extensively used in industrial processes. The aim of this paper is to describe a novel ultrasonic sensor designed to monitor physical–chemical changes that occur in wines stored in industrial tanks. Essentially, the sensor consists of an ultrasonic transducer in contact with a buffer rod, mounted inside a stainless steel tube section. This structure allows the ultrasonic sensor to be directly installed in stainless steel tanks of an industrial plant. The operating principle of this design is based on the measurement of ultrasonic velocity of propagation. To test its proper operation, the sensor has been used to measure changes of concentration in aqueous samples and to monitor the progress of a malolactic fermentation of red wines in various commercial wineries. Results show the feasibility of using this sensor for monitoring malolactic fermentations in red wines placed in industrial tanks.Postprint (author's final draft

The values of intrapleural pressure before the removal of chest tube in non-complicated pulmonary lobectomies

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Concerted involvement of Cdx/Hox genes and Wnt signaling in morphogenesis of the caudal neural tube and cloacal derivatives from the posterior growth zone

Decrease in Cdx dosage in an allelic series of mouse Cdx mutants leads to progressively more severe posterior vertebral defects. These defects are corrected by posterior gain of function of the Wnt effector Lef1. Precocious expression of Hox paralogous 13 genes also induces vertebral axis truncation by antagonizing Cdx function. We report here that the phenotypic similarity also applies to patterning of the caudal neural tube and uro-rectal tracts in Cdx and Wnt3a mutants, and in embryos precociously expressing Hox13 genes. Cdx2 inactivation after placentation leads to posterior defects, including incomplete uro-rectal septation. Compound mutants carrying one active Cdx2 allele in the Cdx4-null background (Cdx2/4), transgenic embryos precociously expressing Hox13 genes and a novel Wnt3a hypomorph mutant all manifest a comparable phenotype with similar uro-rectal defects. Phenotype and transcriptome analysis in early Cdx mutants, genetic rescue experiments and gene expression studies lead us to propose that Cdx transcription factors act via Wnt signaling during the laying down of uro-rectal mesoderm, and that they are operative in an early phase of these events, at the site of tissue progenitors in the posterior growth zone of the embryo. Cdx and Wnt mutations and premature Hox13 expression also cause similar neural dysmorphology, including ectopic neural structures that sometimes lead to neural tube splitting at caudal axial levels. These findings involve the Cdx genes, canonical Wnt signaling and the temporal control of posterior Hox gene expression in posterior morphogenesis in the different embryonic germ layers. They shed a new light on the etiology of the caudal dysplasia or caudal regression range of human congenital defects.AICR project grant: (08-0199); Dutch Earth and Life Sciences grant: (820.02.005); 6th Framework Programme Network of Excellence `Cells into Organs'; Dutch government grant: (Bsik Program 03038); Fundação para a Ciência e Tecnologia grant: (PTDC/BIA-BCM/110638/2009); Centro de Biologia do Desenvolvimento grant: (POCTI-ISFL-4-664)

Temperature compensation of ultrasonic velocity during the malolactic fermentation process

Ultrasonic properties of materials present a strong dependence on temperature and in turn the ultrasonic velocity of propagation in the material under test. It is precisely for this reason that most ultrasonic measurements are often carried out with thermostated samples by using either water tanks or climate chambers. This approach is viable in a laboratory and when the measured or characterized samples are relatively small. However, this procedure is highly improbable to be applied when in situ measurements in industrial environments must be performed. This goes for the case of, for example, ultrasonic velocity measurements in wine while it is performing malolactic fermentation inside a tank of hundreds of thousands of litres. In this paper two different practical approaches to temperature compensation are studied. Then, the two temperature compensation methods are applied to the measured ultrasonic velocity values along a whole malolactic fermentation process. The results of each method are discussed.Peer ReviewedPostprint (author's final draft

π-Dimerization of Heptathienoacene Radical Cations

Oligothienoacenes, the fused-ring analog of pi-linked oligothiophenes, belong to the most promising candidates for organic electronic applications. This is in part due to their fully planar structure that avoids conformational disorder and allows for densely packed solid-state structures resulting in high charge carrier mobilities. In recent years, there has been a growing interest in the study of the pi-dimerization of conjugated radical cations with a dual purpose: (i) elucidation of the nature of the charge-transport phenomena in p-doped semiconducting polymers and (ii) development of supramolecular bonding ideas for applications in material science, such as actuators. However, the π-dimerization of planar conjugated radical cations in solution is scarce and usually encountered at low temperatures. In this work, we investigate the exceptional pi-dimerization capability showed by radical cations of a heptathienoacene alpha,beta-substituted with four n-decyl side groups (D4T7•+) by using a joint experimental and theoretical approach. D4T7 radical cations are found to exhibit an exceptional ability to form pi-dimer dications even at ambient temperature. Our results evidence the presence of two different transitory oxidized species formed during the course of the one-electron oxidation: (i) different conformations of the [D4T7•+]2 pi-dimer dications and (ii) the intermediate [D4T7]2•+ pi-dimer radical cations.[5] The nature and structure of these transitory species and ultimate pi-dimer dication are rigorously analyzed with the help of the DFT and TD-DFT calculations. Our study would provide valuable guidance for the further development of pi-dimer based supramolecular architectures.Universidad de Málaga. Campus de Excelencia Internacional Andalucía Tech