13 research outputs found
Alimentation
Pour donner une image fidĂšle de lâalimentation des BerbĂšres depuis les origines et suivre son Ă©volution il aurait fallu disposer de documents et de textes qui font malheureusement dĂ©faut, aussi plutĂŽt que de se livrer Ă une Ă©tude diachronique impossible Ă rĂ©diger dans lâĂ©tat actuel de la recherche nous avons choisi de prĂ©senter ce que lâon sait de lâalimentation des PalĂ©oberbĂšres des temps prĂ©historiques antĂ©rieurs Ă lâĂ©levage et Ă lâagriculture puis de regrouper nos connaissances sur lâalime..
Ribosomal protein S6 kinase activity controls the ribosome biogenesis transcriptional program
International audienceS6 kinases (S6Ks) are mechanistic target of rapamycin substrates that participate in cell growth control. S6Ks phosphorylate ribosomal protein S6 (rpS6) and additional proteins involved in the translational machinery, although the functional roles of these modifications remain elusive. Here we analyze the S6K-dependent transcriptional and translational regulation of gene expression by comparing whole-genome microarray of total and polysomal mouse liver RNA after feeding. We show that tissue lacking S6Ks 1 and 2 (S6K1 and S6K2), displays a defect in the ribosome biogenesis (RiBi) transcriptional program after feeding. Over 75% of RiBi factors are controlled by S6K, including Nop56, Nop14, Gar1, Rrp9, Rrp15, Rrp12 and Pwp2 nucleolar proteins. Importantly, the reduced activity of RiBi transcriptional promoters in S6K1;S6K2(-/-) cells is also observed in rpS6 knock-in mutants that cannot be phosphorylated. As ribosomal protein synthesis is not affected by these mutations, our data reveal a distinct and specific aspect of RiBi under the control of rpS6 kinase activity, that is, the RiBi transcriptional program
Les villes au Magrehb-Machrek (XIX-XXe siecles)
Available at INIST (FR), Document Supply Service, under shelf-number : AR 14455 / INIST-CNRS - Institut de l'Information Scientifique et TechniqueSIGLEFRFranc
Identites culturelles dans le Maghreb colonial (19e-20e siecles)
CNRS AR 13170 / INIST-CNRS - Institut de l'Information Scientifique et TechniqueSIGLEFRFranc
Underground and Underwater: Oil Security in France and Britain during the Cold War
International audienceIn the first half of the Cold War several administrations in Western Europe sought to increase the amount of oil and gas that could be made available to their countries. These arrangements aimed to boost their national economies but they were also vital to energy security and molded the management of new discoveries and supplies of hydrocarbons at home and abroad. This paper focuses in particular on the plans outlined by the governments of two former imperial powers, France and Britain; their relationships with the superpowers; and those with neighboring partners and rivals. It shows how these administrations used different strategies of surveillance and diplomacy to gain and retain control of, and access to, strategically vital oil-rich areas, especially those in Algeria and in the North Sea. We conclude that geological exploration, and in particular oil prospecting, became another tool for nations long accustomed to intelligence gathering and surveying in the imperial context, to cater for their national energy security
Internationalism in the Mediterranean 1919 - 1942
Internationalism as a process, as a practice of socioâpolitical organisation and as a principle is a useful tool by which to analyse the development of independence movements in North Africa during the interâwar years. Two internationalist traditions interacted in this process, socialist internationalism and Islamic internationalism, with the former demonstrating the ambiguities inherent in the colonial experience and the latter obliged to interact with it as a result of the integration of North Africa into the colonialist capitalist world. Such an analytical approach is important both to illuminate North African nationalism and to counter more recent and particularistic readings of North African contemporary history