A study of nursing patient care in gestational diabetes during SARS CoV-2 pandemic

Although hyperglycaemia that occurs in pregnancy and resolves after birth has been recognised for over fifty years, worldwide consensus on levels of hyperglycaemic thresholds is incomplete and should be diagnosed as 'gestational diabetes mellitus' (GDM). The involvement of GDM is linked to a number of negative perinatal outcomes, including macrosomia, preterm delivery, pre-eclampsia, and eventually will affect the metabolic wellbeing of the resulting infant in future. A nursing care model for non-communicable disorders in primary hospitals increased therapy compliance, as providers aided by clear guidance and administration flowcharts. Early reports from China find COVID-19 infections among men in Wuhan. Later evidence from 30 jurisdictions outside Hubei demonstrated a drop in male domination, as did young women who were diagnosed with the disease at middle age. The psychological and mental health of mothers with GDM has become a big burden with this pandemic in the COVID-19 world-wide that resulted in serious deaths. However, as far as we know, no study explores the success of nurses or licensed clinical nurses during the SARS CoV-2 pandemic in caring for women with GDM. &nbsp

Survey of approaches for investigation of atherosclerosis in vivo

Although in vitro model systems are useful for investigation of atherosclerosis-associated processes, they represent simplification of complex events that occur in vivo, which involve interactions between many different cell types together with their environment. The use of animal model systems is important for more in-depth insights of the molecular mechanisms underlying atherosclerosis and for identifying potential targets for agents that can prevent plaque formation and even reverse existing disease. This chapter will provide a survey of such animal models and associated techniques that are routinely used for research of atherosclerosis in vivo

Red Beetroot Extract Abrogates Chlorpyrifos-Induced Cortical Damage in Rats

Organophosphorus insecticides including chlorpyrifos (CPF) are mainly used for agriculture, household, and military purposes; their application is associated with various adverse reactions in animals and humans. This study was conducted to evaluate the potential neuroprotective effect of red beetroot methanolic extract (RBR) against CPF-induced cortical damage. Twenty-eight adult male Wistar albino rats were divided into 4 groups (n=7 in each group): the control group was administered physiological saline (0.9% NaCl), the CPF group was administered CPF (10 mg/kg), the RBR group was administered RBR (300 mg/kg), and the RBR+CPF group was treated with RBR (300 mg/kg) 1 hr before CPF (10 mg/kg) supplementation. All groups were treated for 28 days. Rats exposed to CPF exhibited a significant decrease in cortical acetylcholinesterase activity and brain-derived neurotrophic factor and a decrease in glial fibrillary acidic protein. CPF intoxication increased lipid peroxidation, inducible nitric oxide synthase expression, and nitric oxide production. This was accompanied by a decrease in glutathione content and in the activities of glutathione peroxidase, glutathione reductase, superoxide dismutase, and catalase in the cortical tissue. Additionally, CPF enhanced inflammatory response, indicated by increased levels and expression of interleukin-1β and tumor necrosis factor-α. CPF triggered neuronal apoptosis by upregulating Bax and caspase-3 and downregulating Bcl-2. However, RBR reversed the induced neuronal alterations following CPF intoxication. Our findings suggest that RBR can minimize and prevent CPF neurotoxicity through its antioxidant, anti-inflammatory, and antiapoptotic activities