Cyano and CF3 Derivatives of 2-Aryl- and 2-Thienylquinazoline: Synthesis and Study of Optical Properties

This work was supported by the Russian Foundation for Basic Research (grant # 18-03-00112) and Russian Science Foundation (project # 19-73-10144)

Synthetic approaches to 2-aryl/hetaryl- and 2-(hetaryl)ylidene derivatives of fluorinated 1,3-benzothiazin-4-ones

A series of 2-hetaryl- and 2-(hetaryl)ylidene substituted 5-fluoro-8-nitro-1,3-benzothiazin-4-ones was synthesized by interaction of 2,6-difluoro-3-nitrobenzoylisothiocyanate with C-nucleophiles. Cyclocondensation of polyfluorobenzoylchlorides with aryl and hetaryl thioamides represents new approach to 1,3-benzothiazin-4-ones. Some compounds proved to be promising for further development of tuberculostatic agents

Antiviral Agents – Benzazine Derivatives

[Figure not available: see fulltext.] The review outlines the results of studies of the antiviral activity of quinoline, quinoxaline, and quinazoline derivatives published over the past 5 years. The supplied data indicate the enormous potential of benzazines for the design of effective antiviral drugs. © 2021, Springer Science+Business Media, LLC, part of Springer Nature.This work was supported by the Ministry of Science and Higher Education of the Russian Federation (project No. FEUZ-2020-0058 (N687.42B.223/20))

Effect of the Mechanism Transfer Function on the Positioning Law

Parametric synthesis of mechanical system consisting of actuator, transfer mechanism and control device is considered. Planar and spatial mechanisms with one degree of freedom can be included in the system. Mechanism structure and the type of the actuator are considered to be given preliminary.     Keywords: synthesis, mechanism, drive, contro

(E)-2-(hydroxystyryl)-3-phenylquinazolin-4(3H)-ones: Synthesis, photochemical and luminescent properties

The new (E)-2-(hydroxyarilethenyl)-3-phenylquinazolin-4(3H)-ones with various substituents in phenyl fragment were synthesized. The effect of electron donor and acceptor substituents (±M) in quinazolinones on luminescence intensity and dual emission in 550-650-nm wavelength range was shown. The fact of the reversible photo/thermal E-Z isomerization for several substances was established. The (E)-2-(5-chloro-2-hydroxystyryl)-3-phenylquinazolin-4(3H)-one had shown the best combination of photochemical (E-Z isomerization) and photophysical properties. The (E)-2-(2-hydroxy-5-morpholinostyryl)-3-phenylquinazolin-4(3H)-one had revealed the best ESIPT-luminescence (Φrel = 5.3 %). © Arkat. All Rights Reserved.Russian Foundation for Basic Research, RFBR: 18-03-00112This work was supported by the Russian Foundation for Basic Research (grant 18-03-00112). Analytical studies were carried out using equipment of the Center for Joint Use SSpectroscopy and ?nalysis of Organic Compounds ? at the Postosvky Institute of Organic Synthesis of the Russian Academy of Sciences (Ural Branch)

5-SALICYLIDENHYDRAZINO DERIVATIVES OF 2-ARYL-[1,2,4]TRIAZOLO[1,5-c]QUINAZOLINES

Funding from Ministry of Science and Higher Education of the Russian Federation, project FEUZ-2023-0021

2-Aryl and 2-Thienylbenzazines With Luminescent Properties

This work was supported by the Russian Foundation for Basic Research (grant № 18-03-00112)

2-(2-Hydroxyphenyl)quinazolinone dyes and their difluoroboron complexes: synthesys and photophysical properties

This work was supported by the Russian Foundation for Basic Research (grant № 19-33-90014)