Renewing regulatory practices: The case of stem cells

This paper examines the political decisions made by three countries - Denmark, the Netherlands, and Germany - about stem cell research. It recommends directing the regulatory practices away from today's practice, based on regulation of technological frameworks, and towards a regulatory policy based on technological road-mapping. Regulatory practices would thus be based on the content of the technologies in question, and on the vision they seem to show. Its conclusion suggests a positive side-effect of such a shift in the regulatory paradigm: that technological road-mapping can be used as a communication tool to deal with priorities in the healthcare system when technologies are at an embryonic state.</p

Annotation of putative circadian rhythm-associated genes in Diaphorina citri (Hemiptera: Liviidae)

The circadian rhythm involves multiple genes that generate an internal molecular clock, allowing organisms to anticipate environmental conditions produced by the Earth's rotation on its axis. Here, we present the results of the manual curation of 27 genes that are associated with circadian rhythm in the genome of Diaphorina citri, the Asian citrus psyllid. This insect is the vector for the bacterial pathogen Candidatus Liberibacter asiaticus (CLas), the causal agent of citrus greening disease (Huanglongbing). This disease severely affects citrus industries and has drastically decreased crop yields worldwide. Based on cry1 and cry2 identified in the psyllid genome, D. citri likely possesses a circadian model similar to the lepidopteran butterfly, Danaus plexippus. Manual annotation will improve the quality of circadian rhythm gene models, allowing the future development of molecular therapeutics, such as RNA interference or antisense technologies, to target these genes to disrupt the psyllid biology. © 2022 GigaScience Press. All Rights Reserved.Open access journalThis item from the UA Faculty Publications collection is made available by the University of Arizona with support from the University of Arizona Libraries. If you have questions, please contact us at [email protected]