2 research outputs found
Rat Mesentery Angiogenesis Assay
The adult rat mesentery window angiogenesis assay is biologically appropriate and is exceptionally well suited to the
study of sprouting angiogenesis in vivo [see review papers], which is the dominating form of angiogenesis in human tumors and non-tumor
tissues, as discussed in invited review papers1,2. Angiogenesis induced in the membranous mesenteric parts by intraperitoneal (i.p.) injection of a pro-angiogenic factor can be modulated
by subcutaneous (s.c.), intravenous (i.v.) or oral (p.o.) treatment with modifying agents of choice. Each membranous part of the mesentery is
translucent and framed by fatty tissue, giving it a window-like appearance