336 research outputs found

    Phorbic Acid Biosynthesis in the Latex Vessel System of Euphorbia

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    Escape and Naturalization of Tagetes patula in Western Ethiopia

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    This study was carried out on an introduced ornamental - Tagetes patula L., which has escaped cultivation and has been naturalized in Benishangul-Gumuz National Regional State (bgnrs), western Ethiopia. Another introduced ornamental - Zinnia elegans Jacq. and the native species - Bidens prestinaria (Sch. Bip.) Cufod. were included in some of the experiments for comparison. Pre-prepared semi-structured interviews were administered, on the arrival, spread and impact of T. patula. The result showed that the escaped T. patula has no negative impact on the daily life of people, except weeding in farmlands. T. patula was found associated with species that prefer shade and moisture in semi-natural vegetation. It produces a large number of relatively small propagules and has a seed bank. These characters might enhance its invasive ability and make it a potential threat to grazing fields and natural landscapes in western Ethiopia. The result of fire simulation experiment, however, revealed that fire had an effect on seed germination, as there was no seed germination at higher temperature treatment (120°C/5 minutes). The annual fire occurring existing in the woodlands of bgnrs might not allow invasion by the species that are not adapted to fire, like T. patula and Z. elegans. In the absence of annual woodland fire, invasion of the woodland vegetation in bgnrs by T. patula and Z. elegans is most likely to occur

    Managing Access to Biobanks:How Can We Reconcile Privacy and Public Interests in Genetic Research?

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    This article is concerned with the ultimate objectives of genetic biobanks set up to promote the public interest—being the sharing of samples and data for medical research—and the consequences for personal privacy of realising them. Our aim is to chart the values, interests and principles in play, to consider the challenges of realizing biobanking objectives on a global scale, and to propose viable ways forward that ensure, as far as possible, that access provisions remain fit for purpose throughout the entire life of a biobank, while adequately protecting the privacy interests at stake. It is argued that key features in any robust access model must include mechanisms to (a) maintain participant trust in management of the resource and to measure and respond to participants’ expectations, (b) facilitate and promote the sharing of benefits, and (c) respond timeously and effectively to new challenges

    Desmoplastic myxoid tumor of pineal region, SMARCB1-mutant, in young adult

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    We present a young adult woman who developed a myxoid tumor of the pineal region having a SMARCB1 mutation, which was phenotypically similar to the recently described desmoplastic myxoid, SMARCB1-mutant tumor of the pineal region (DMT-SMARCB1). The 24-year-old woman presented with headaches, nausea, and emesis. Neuroimaging identified a hypodense lesion in CT scans that was T1-hypointense, hyperintense in both T2-weighted and FLAIR MRI scans, and displayed gadolinium enhancement. The resected tumor had an abundant, Alcian-blue positive myxoid matrix with interspersed, non-neoplastic neuropil-glial-vascular elements. It immunoreacted with CD34 and individual cells for EMA. Immunohistochemistry revealed loss of nuclear INI1 expression by the myxoid component but its retention in the vascular elements. Molecular analyses identified a SMARCB1 deletion and DNA methylation studies showed that this tumor grouped together with the recently described DMT-SMARCB1. A cerebrospinal fluid cytologic preparation had several cells morphologically similar to those in routine and electron microscopy. We briefly discuss the correlation of the pathology with the radiology and how this tumor compares with other SMARCB1-mutant tumors of the nervous system
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