¿Perciben del mismo modo alumnado y profesorado el desarrollo de competencias docentes? El caso de un grado de ciencias de la actividad física y el deporte

La competencia docente hace referencia a la capacidad del profesorado para resolver con éxito las exigencias complejas que se le planteen en el contexto educativo. Estas competencias deben ser adquiridas, en parte, durante la formación inicial del profesorado. Esta investigación pretende comparar como perciben el profesorado y alumnado el desarrollo de competencias docentes en un grado de Ciencias de la Actividad física y el Deporte. Para ello, se pasó en el curso 2014-15 una escala de valoración autoadministrada a 65 estudiantes de 4º curso y otra a 29 profesores/as. Existen diferencias significativas en la percepción del profesorado y alumnado en 24 de las 46 competencias del cuestionario. En todas las competencias el alumnado proporcionó una puntuación media más elevada que el profesorado, excepto en 9 competencias transversales. Resulta necesario seguir profundizando en las razones de esta diferencia de percepción realizando entrevistas y grupos focales que aporten información más cualitativa

The Color of Noise and Weak Stationarity at the NREM to REM Sleep Transition in Mild Cognitive Impaired Subjects

In Older Adults (OAs), Electroencephalogram (EEG) slowing in frontal lobes and a diminished muscle atonia during Rapid Eye Movement sleep (REM) have each been effective tracers of Mild Cognitive Impairment (MCI), but this relationship remains to be explored by non-linear analysis. Likewise, data provided by EEG, EMG (Electromyogram) and EOG (Electrooculogram)—the three required sleep indicators—during the transition from REM to Non-REM (NREM) sleep have not been related jointly to MCI. Therefore, the main aim of the study was to explore, with results for Detrended Fluctuation Analysis (DFA) and multichannel DFA (mDFA), the Color of Noise (CN) at the NREM to REM transition in OAs with MCI vs. subjects with good performances. The comparisons for the transition from NREM to REM were made for each group at each cerebral area, taking bilateral derivations to evaluate interhemispheric coupling and anteroposterior and posterior networks. In addition, stationarity analysis was carried out to explore if the three markers distinguished between the groups. Neuropsi and the Mini-Mental State Examination (MMSE) were administered, as well as other geriatric tests. One night polysomnography was applied to 6 OAs with MCI (68.1 ± 3) and to 7 subjects without it (CTRL) (64.5 ± 9), and pre-REM and REM epochs were analyzed for each subject. Lower scores for attention, memory and executive funcions and a greater index of arousals during sleep were found for the MCI group. Results confirmed that EOGs constituted significant markers of MCI, increasing the CN for the MCI group in REM sleep. The CN of the EEG from the pre-REM to REM was higher for the MCI group vs. the opposite for the CTRL group at frontotemporal areas. Frontopolar interhemispheric scaling values also followed this trend as well as right anteroposterior networks. EMG Hurst values for both groups were lower than those for EEG and EOG. Stationarity analyses showed differences between stages in frontal areas and right and left EOGs for both groups. These results may demonstrate the breakdown of fractality of areas especially involved in executive functioning and the way weak stationarity analyses may help to distinguish between sleep stages in OAs

Re-thinking the Etiological Framework of Neurodegeneration

Neurodegenerative diseases are among the leading causes of disability and death worldwide. The disease-related socioeconomic burden is expected to increase with the steadily increasing life expectancy. In spite of decades of clinical and basic research, most strategies designed to manage degenerative brain diseases are palliative. This is not surprising as neurodegeneration progresses "silently" for decades before symptoms are noticed. Importantly, conceptual models with heuristic value used to study neurodegeneration have been constructed retrospectively, based on signs and symptoms already present in affected patients;a circumstance that may confound causes and consequences. Hence, innovative, paradigm-shifting views of the etiology of these diseases are necessary to enable their timely prevention and treatment. Here, we outline four alternative views, not mutually exclusive, on different etiological paths toward neurodegeneration. First, we propose neurodegeneration as being a secondary outcome of a primary cardiovascular cause with vascular pathology disrupting the vital homeostatic interactions between the vasculature and the brain, resulting in cognitive impairment, dementia, and cerebrovascular events such as stroke. Second, we suggest that the persistence of senescent cells in neuronal circuits may favor, together with systemic metabolic diseases, neurodegeneration to occur. Third, we argue that neurodegeneration may start in response to altered body and brain trophic interactions established via the hardwire that connects peripheral targets with central neuronal structures or by means of extracellular vesicle (E\-mediated communication. Lastly, we elaborate on how lifespan body dysbiosis may be linked to the origin of neurodegeneration. We highlight the existence of bacterial products that modulate the gut-brain axis causing neuroinflammation and neuronal dysfunction. As a concluding section, we end by recommending research avenues to investigate these etiological paths in the future. We think that this requires an integrated, interdisciplinary conceptual research approach based on the investigation of the multimodal aspects of physiology and pathophysiology. It involves utilizing proper conceptual models, experimental animal units, and identifying currently unused opportunities derived from human data. Overall, the proposed etiological paths and experimental recommendations will be important guidelines for future cross-discipline research to overcome the translational roadblock and to develop causative treatments for neurodegenerative diseases

A retrospective cohort study of risk factors for mortality among nursing homes exposed to COVID-19 in Spain

Long-term care (LTC) facilities have shown remarkably high mortality rates during the coronavirus disease 2019 (COVID-19) outbreak in many countries1, and different risk factors for mortality have been identified in this setting2–5. Using facilities as the unit of analysis, we investigated multiple variables covering facility characteristics and socioeconomic characteristics of the geographic location to identify risk factors for excess mortality from a comprehensive perspective. Furthermore, we used a clustering approach to detect patterns in datasets and generate hypotheses regarding potential relationships between types of nursing homes and mortality trends. Our retrospective analysis included 167 nursing homes providing LTC to 8,716 residents during the COVID-19 outbreak in Catalonia (northeast Spain). According to multiple regression analysis, COVID-19-related and overall mortality at the facility level were significantly associated with a higher percentage of patients with complex diseases, lower scores on pandemic preparedness measures and higher population incidence of COVID-19 in the surrounding population. When grouping nursing homes into eight clusters based on common features, we found higher mortality rates in four clusters, mainly characterized by a higher proportion of residents with complex chronic conditions or advanced diseases, lower scores on pandemic preparedness, being located in rural areas and larger capacity, respectively

Photoferrotrophy: Remains of an ancient photosynthesis in modern environments

© 2017 Camacho, Walter, Picazo and Zopfi. Photoferrotrophy, the process by which inorganic carbon is fixed into organic matter using light as an energy source and reduced iron [Fe(II)] as an electron donor, has been proposed as one of the oldest photoautotrophic metabolisms on Earth. Under the iron-rich (ferruginous) but sulfide poor conditions dominating the Archean ocean, this type of metabolism could have accounted for most of the primary production in the photic zone. Here we review the current knowledge of biogeochemical, microbial and phylogenetic aspects of photoferrotrophy, and evaluate the ecological significance of this process in ancient and modern environments. From the ferruginous conditions that prevailed during most of the Archean, the ancient ocean evolved toward euxinic (anoxic and sulfide rich) conditions and, finally, much after the advent of oxygenic photosynthesis, to a predominantly oxic environment. Under these new conditions photoferrotrophs lost importance as primary producers, and now photoferrotrophy remains as a vestige of a formerly relevant photosynthetic process. Apart from the geological record and other biogeochemical markers, modern environments resembling the redox conditions of these ancient oceans can offer insights into the past significance of photoferrotrophy and help to explain how this metabolism operated as an important source of organic carbon for the early biosphere. Iron-rich meromictic (permanently stratified) lakes can be considered as modern analogs of the ancient Archean ocean, as they present anoxic ferruginous water columns where light can still be available at the chemocline, thus offering suitable niches for photoferrotrophs. A few bacterial strains of purple bacteria as well as of green sulfur bacteria have been shown to possess photoferrotrophic capacities, and hence, could thrive in these modern Archean ocean analogs. Studies addressing the occurrence and the biogeochemical significance of photoferrotrophy in ferruginous environments have been conducted so far in lakes Matano, Pavin, La Cruz, and the Kabuno Bay of Lake Kivu. To date, only in the latter two lakes a biogeochemical role of photoferrotrophs has been confirmed. In this review we critically summarize the current knowledge on iron-driven photosynthesis, as a remains of ancient Earth biogeochemistry

Diversity, dynamics and activity of Epsilonproteobacteria in a stratified karstic lake. Implications in carbon and sulfur cycles

This doctoral thesis studies the abundance, diversity, seasonal dynamics and activity of Epsilonproteobacteria in a meromictic basin of Lake Banyoles during three year cycles. We applied a complementary array of molecular techniques to resolve the identity and ecological role of Epsilonproteobacteria in the system, with special focus on the contribution of these microorganisms on linking C and S cycles. Our results pointed to a clear seasonality of Epsilonproteobacteria, with maximal abundances at the redoxcline and upper monimolimnion in winter. Furthermore, results revealed the predominance of sequences affiliated to genus Arcobacter, and clearly indicated that Epsilonproteobacteria actively assimilated CO2 in the dark thus being responsible of the high rates of dark carbon fixation measured at the redoxcline in winter. Additional analyses provided additional evidence that the dominant member of the epsilonproteobacterial community is a chemolithotrophic, sulfide-oxidizing member of the genus Arcobacter, distantly related to its marine counterpart Candidatus A.sulfidicus.En aquesta tesi doctoral s’ha estudiat l’abundància, diversitat, dinàmica estacional i activitat dels Epsilonproteobacteria en una cubeta meromíctica de l’Estany de Banyoles durant tres cicles anuals. L’estudi combina diferents tècniques moleculars per resoldre la identitat i funció ecològica d’aquests microorganismes al sistema, amb especial atenció a la seva contribució als cicles del C i del S. Els resultats van mostrar una clara estacionalitat en l’abundància d’Epsilonproteobacteria amb màxims hivernals a la redoxclina i al monimolimnion, i van revelar un predomini de seqüències afiliades al gènere Arcobacter. A més, els resultats van demostrar que els Epsilonproteobacteria assimilen activament CO2 en la foscor, essent els responsables de les elevades taxes de fixació fosca de C mesurades a la redoxclina a l’hivern. Anàlisis moleculars complementàries van resoldre que el membre predominant de la comunitat estudiada és un microorganisme quimiolitotròfic i oxidador de sofre del gènere Arcobacter, filogenèticament emparentat amb l’espècie marina Candidatus A.sulfidicus

Donación de órganos desde una perspectiva del personal médico

Organ donation and the transplant process allow improving the health status and quality of life of patients with some pathologies. Donor screening is one of the most important points of the entire protocol, it is a procedure that requires not only the good disposition of the general population, but also well-organized health personnel with knowledge of the process. Aim. Determine the factors that hinder the organ donation process in medical personnel. Methodology. A systematic review was conducted to discover the factors that have contributed to the low rates of organ donation, from the perspective of medical personnel. 28 articles from journals indexed in Crossref, PubMed, Elsevier, Medline and Scielo were selected, in addition to the official pages. The search was performed using keywords (donation, transplant, brain death and medical personnel) in spanish and english. Results. 28 indexed articles and official pages were reviewed where the ignorance of medical personnel to identify possible donors and related legislation, the lack of personnel, infrastructure and medical organization, as well as attitude are determining factors in the low donation of Organs Conclusions. it is necessary to implement strategies for a better knowledge of the organ donation process for medical personnel, in addition to organizational training and constant feedback. otherwise the results will continue as non-positive.  La donación de órganos y el proceso de trasplante permiten la mejora del estado de salud y de la calidad de vida de paciente con algunas patologías. La detección de donantes es uno de los puntos más importantes de todo el protocolo, es un procedimiento que necesita no solo de la buena disposición de la población general, sino también de personal de salud bien organizado y con conocimiento del proceso. Objetivo. Determinar los factores que dificultan el proceso de donación de órganos en el personal médico. Métodología. Se realizó una revisión sistemática para conocer los factores que han contribuido a las bajas tasas de donación de órganos, desde una perspectiva del personal médico. Se eligieron 28 artículos de revistas indexadas en Crossref, PubMed, Elsevier, Medline y Scielo, además de páginas oficiales. La búsqueda se realizó mediante palabras clave (Donación, Trasplante, Muerte encefálica y Personal Médico) en español e inglés. Resultados. Se revisaron 28 artículos indexados y paginas oficiales donde el desconocimiento del personal médico para identificar potenciales donadores y la legislación referente al tema, la falta de personal y organización médica, así como la actitud son factores que dificultan el proceso de donación de órganos. Conclusiones. Se requiere implementar estrategias para un mayor conocimiento del proceso de donación de órganos para el personal médico, además de capacitación organizacional y constante retroalimentación, de lo contario los resultados continuaran como no positivos.