Osteolysis of the Greater Trochanter Caused by a Foreign Body Granuloma Associated with the Ethibond® Suture after Total Hip Arthroplasty

The present case shows a case of progression of osteolysis of the greater trochanter caused by a foreign body granuloma associated with the number 5 Ethibond suture in cementless THA with the direct lateral approach that was completely healed by removal of the Ethibond suture. A 55-year-old Japanese woman with secondary osteoarthritis caused by acetabular dysplasia underwent left cementless THA with the direct lateral approach. After setting of the total hip prosthesis, the gluteus medius muscle and vastus lateralis muscle were reattached to the greater trochanter through two bone tunnels using number 5 Ethibond EXCEL sutures. The left hip pain disappeared after surgery, but the bone tunnels enlarged gradually and developed osteolysis at 10 weeks. The removal of the Ethibond sutures and debridement improved the osteolysis. Histological examination showed the granuloma reaction to a foreign body with giant cell formation. The Ethibond suture has the lowest inflammatory tissue reaction and relatively high tension strength among nonabsorbable suture materials. However, number 5 Ethibond has the potential to cause osteolysis due to a foreign body granuloma, as in the present case

RELATIONSHIP BETWEEN GLENOHUMERAL JOINT STABILITY AND GLENOID DEPTH : A CADAVERIC STUDY

The purpose is to directly measure the glenoid depth and clarify its relationship with the stability ratio. We used 9 fresh-frozen cadaveric shoulders (mean age : 66 years, 5 males and 4 females). Naked glenohumeral joint was investigated. The shoulder was fixed to the custom designed measurement device with the glenoid surface horizontal to the floor and the humerus with 45° abduction and 35° external rotation. The stability ratio was 27.1 ± 6.5% (mean ± standard deviation) at 90° in the anterior, 26.2 ± 7.9% at 280° in the posterior (the minimum), 48.3 ± 10.4 at 10° in the superior, and 52.9 ± 12.5% at 180° in the inferior (the maximum) direction. The mean glenoid depth was 1.4 ± 0.3 mm at 90° and 270°, and 3.4 ± 0.9 and 3.3 ± 0.9 mm at 0° and 180°, respectively, showing that both the stability ratio and glenoid depth were minimal in the anterior 3 o’clock direction. The stability ratio increased as the glenoid depth increased, and the correlation coefficient was 0.92 ( p=0.01), showing a markedly strong positive correlation. The glenohumeral joint is most unstable in the anterior direction in terms of the bony stability

H3K27me3 demethylases alter HSP22 and HSP17.6C expression in response to recurring heat in Arabidopsis

Acclimation to high temperature increases tolerance of heat shock in plants. Here the authors show that JUMONJI H3K27me3 demethylases are needed for heat acclimation in Arabidopsis and act at loci encoding HEAT SHOCK PROTEINS to facilitate induction upon heat stress