2004ネン ナンキョク ニオケル イリョウ イガク ケンキュウ ニカンスル ケンキュウ シュウカイ ノ ホウコク

004年の「南極における医療・医学研究集会」が8月28日,国立極地研究所で開催された.主な内容は「南極の高所がヒトに与える影響」,「南極でのストレスがアミノ酸脂肪酸代謝に与える影響」,「越冬基地におけるレジオネラ菌調査」,「南極における紫外線障害とその対策」,「46次隊の医学研究計画」であった.16施設から合計22名が参加し,口頭発表10演題,ポスター発表1演題,文書発表1演題について,活発な討論が行われた.A meeting on Antarctic Medical Research was held at NIPR on August 28, 2004. Twenty two members participated in the meeting with ten oral presentations, one poster presentation and one report paper. The main subjects were The human responses in the Antarctic highland", The influence of the cold stress on the amino acids and lipid metabolism", Legionella contamination at the Antarctic wintering stations". The JARE-46 medical research program" was also reported and discussed

Meeting on Antarctic Medical Research in 2004

A meeting on Antarctic Medical Research was held at NIPR on August 28, 2004. Twenty two members participated in the meeting with ten oral presentations, one poster presentation and one report paper. The main subjects were The human responses in the Antarctic highland", The influence of the cold stress on the amino acids and lipid metabolism", Legionella contamination at the Antarctic wintering stations". The JARE-46 medical research program" was also reported and discussed

National trends in the outcomes of subarachnoid haemorrhage and the prognostic influence of stroke centre capability in Japan: retrospective cohort study

Objectives To examine the national, 6-year trends in in-hospital clinical outcomes of patients with subarachnoid haemorrhage (SAH) who underwent clipping or coiling and the prognostic influence of temporal trends in the Comprehensive Stroke Center (CSC) capabilities on patient outcomes in Japan.Design Retrospective study.Setting Six hundred and thirty-one primary care institutions in Japan.Participants Forty-five thousand and eleven patients with SAH who were urgently hospitalised, identified using the J-ASPECT Diagnosis Procedure Combination database.Primary and secondary outcome measures Annual number of patients with SAH who remained untreated, or who received clipping or coiling, in-hospital mortality and poor functional outcomes (modified Rankin Scale: 3–6) at discharge. Each CSC was assessed using a validated scoring system (CSC score: 1–25 points).Results In the overall cohort, in-hospital mortality decreased (year for trend, OR (95% CI): 0.97 (0.96 to 0.99)), while the proportion of poor functional outcomes remained unchanged (1.00 (0.98 to 1.02)). The proportion of patients who underwent clipping gradually decreased from 46.6% to 38.5%, while that of those who received coiling and those left untreated gradually increased from 16.9% to 22.6% and 35.4% to 38%, respectively. In-hospital mortality of coiled (0.94 (0.89 to 0.98)) and untreated (0.93 (0.90 to 0.96)) patients decreased, whereas that of clipped patients remained stable. CSC score improvement was associated with increased use of coiling (per 1-point increase, 1.14 (1.08 to 1.20)) but not with short-term patient outcomes regardless of treatment modality.Conclusions The 6-year trends indicated lower in-hospital mortality for patients with SAH (attributable to better outcomes), increased use of coiling and multidisciplinary care for untreated patients. Further increasing CSC capabilities may improve overall outcomes, mainly by increasing the use of coiling. Additional studies are necessary to determine the effect of confounders such as aneurysm complexity on outcomes of clipped patients in the modern endovascular era