67 research outputs found
The disruption of proteostasis in neurodegenerative diseases
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- Publication venue
- 'American Institute of Mathematical Sciences (AIMS)'
- Publication date
- 01/01/2015
- Field of study
Get PDFCells count on surveillance systems to monitor and protect the cellular proteome which, besides being highly heterogeneous, is constantly being challenged by intrinsic and environmental factors. In this context, the proteostasis network (PN) is essential to achieve a stable and functional proteome. Disruption of the PN is associated with aging and can lead to and/or potentiate the occurrence of many neurodegenerative diseases (ND). This not only emphasizes the importance of the PN in health span and aging but also how its modulation can be a potential target for intervention and treatment of human diseases.info:eu-repo/semantics/publishedVersio
Drugs for insomnia and improving quality of life (QOL): research and development of ramelteon, an MT1/MT2 -receptor agonist
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- Publication venue
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- 01/01/2008
- Field of study
No full textGenome-wide maps of nucleosomes of the trichostatin A treated and untreated archiascomycetous yeast <em>Saitoella complicata</em>
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No full textComparison of transcriptomes of enlarged spheroplasts of <em>Erythrobacter litoralis</em> and <em>Lelliottia amnigena</em>
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No full textDNA replication and cell enlargement of Enterococcus faecalis protoplasts
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No full textPanic disorders: The role of genetics and epigenetics
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No full textDDRs: receptors that mediate adhesion, migration and invasion in breast cancer cells
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- 'American Institute of Mathematical Sciences (AIMS)'
- Publication date
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- Field of study
No full textDiesel exhaust pollution: chemical monitoring and cytotoxicity assessment
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No full textAnalysis of transcatheter arterial infusion chemotherapy of cisplatin in advanced hepatocellular carcinoma: relationship between imaging findings (contrast-enhanced CT and angiography) and the results of TAI
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No full textEsophageal cancer research today and tomorrow: Lessons from algae and other perspectives
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