<span style="font-size:14.0pt;line-height: 115%;font-family:"Times New Roman";mso-fareast-font-family:"Times New Roman"; color:black;mso-ansi-language:EN-IN;mso-fareast-language:EN-IN;mso-bidi-language: HI" lang="EN-IN">Eco-friendly Pest Management Using Monoterpenoids-III: Antibacterial Efficacy of Carvacrol Derivatives^#</span>

1086-1089<span style="font-size:14.0pt;line-height: 115%;font-family:" times="" new="" roman";mso-fareast-font-family:"times="" roman";="" color:black;mso-ansi-language:en-in;mso-fareast-language:en-in;mso-bidi-language:="" hi"="" lang="EN-IN">Monoterpenoids are the natural products having pest management potency against different agricultural as well as public health pests. Ether and ester derivatives of carvacrol, [2-methyl-5- (1-methyl ethyl) phenol], a natural phenolic monoterpenoid, were synthesized and evaluated for their antibacterial activity against B.megaterium, B.japonicum ,B.polymyxa and B. substilits to establish structure-activity relationships. In overall studies, carvacrol esters exhibited better antibacterial potency and efficacy than ethers. An introduction of aliphatic side chains with increasing methylene group and olefine double bond reflected least effect on activity. However, aromatic moiety, additional olefinic bond and also carboxylic group in the side chain resulted in the compounds with improved and better antibacterial potency over the parent molecule.</span

Eco-friendly Pest Management Using Monoterpenoids II—Antifungal Efficacy of Menthol Derivatives

990-995<span style="font-size:14.0pt;line-height: 115%;font-family:" times="" new="" roman";mso-fareast-font-family:"times="" roman";="" color:black;mso-ansi-language:en-in;mso-fareast-language:en-in;mso-bidi-language:="" hi"="" lang="EN-IN">Ether and ester derivatives of menthol, [5-methyl-2-(1-methylethyl) cyc1o hexanol] , a natural monoterpenoid are synthesized and evaluated for antifungal potency against Aspergillus niger, Aspergillus oryzae, Fusarium oxysporum , and Alternaria alternata to study structure activity relationships. Ethylene dimer ether derivative is observed to be the most potent against all fungal species. Benzyl ether derivative is found to be more active than allyl ether derivative. In simple esters, cinnamate derivative is more activity enhancing against Aspergillus oryz, Alternaria alternala and Fusarium oxysporum, while benzoate is better against Aspergillus niger. Among diesters, malonate is more active against all the test fungi except F. oxysporum. Against A. alternata , coupling of monoterpenoid molecules through diester bridge containing one methylene group (malonate) is more active. Among simple ethers and esters, respectively, menthyl benzyl ether and menthyl cinnamate reflects the highest activity against F. oxysporum.</span