Best Fit Method of Sample Selection in Data Hiding and Extraction

Today data security and its transmission over the wireless network need special attention. Intruder always has a watch on sensitive data transmitted over a wireless network. This work proposes an approach that minimizes the quantization error between the original and result carrier by selecting optimize samples during Data Hiding. Propose work find out best matching carrier components during the data hiding process. Results also imply that achieved results are far better than any other steganographic method

CRITICAL REVIEW OF DRUG INDUCED CARDIOTOXICITY W.S.R. TO GARA VISHA

Cardiotoxicity is a condition when there is damage to heart muscles by a toxin. It has many causes but drug induced cardiotoxicity is more common. Agadtantra is one of the eight clinical branches of Ayurveda. It deals with Visha, their characteristics, manifestations and treatment. Cardiovascular diseases and cancer are the most common causes of death in India. Out of which, heart failure is a major cause. Cardiotoxicity is one reason for heart failure; it may cause due to some common drug categories like anticancer agents, monoclonals, antihypertensives, antidepressants etc. No specific antidote treatment for drug induced cardiotoxicity is available till now. Currently it is managed by using general line of treatment and symptomatic treatment. Gara visha (Artificial Poison) is the type of Samyogaja visha (Unnatural poison or chemically prepared poison) which is prepared by the combination of either poisonous or non-poisonous substances. Thorough literature review has been conducted on modern aspect of drug induced cardiotoxicity and classical aspect of Gara visha. It is found that there is positive correlation between drugs induced cardiotoxicity and Gara visha. Hence, it is concluded that various treatment modalities useful in Gara visha can be effective in drug induced cardiotoxicity. Present article will be helpful for researchers to explore different dimensions of treatment of drug induced cardiotoxicity

Uraria picta: A comprehensive review on evidences of utilization and strategies of conservation

Uraria picta (Jacq.) DC. (Prishnaparni) is one of the most important medicinal plants used in different traditional systems of medicines including the Ayurveda and Traditional Chinese medicine. The major use of this plant was found in the most popular Ayurvedic formulation “Dashmula” and in several many other important Ayurvedic formulations. IUCN placed this woody herb in the least concern category as per version 3.1. It has extensive therapeutic uses and pharmacological activities. Though this plant is a source of many phytochemicals, the uses are uncertain because the raw plant parts or crude extracts are being used in all formulations. Therefore, extensive investigations are necessary to focus on the identification of these phytochemicals. It is an urgent need to give special attention to collecting various aspects and more efforts are required in all areas for utilization and conservation of this valuable medicinal herb. Herein, a compilation of all information with various aspects has been presented, including the authors published work on Uraria picta. This review pursues attention towards biological activity, phytochemical profile, utilization, propagation and conservation of Uraria picta

ASSESSMENT AND MONITORING OF AGRICULTURAL DROUGHTS IN MAHARASHTRA USING METEOROLOGICAL AND REMOTE SENSING BASED INDICES

Drought is a recurring climatic event characterized by slow onset, a gradual increase in its intensity, and persistence for a long period depending upon the availability of water. Droughts, broadly classified into meteorological, hydrological and agricultural drought, which are interconnected to each other. India, being an agriculture based economy depends primarily on agriculture production for its economic development and stability. The occurrence of agriculture drought affects the agricultural yield, which affects the regional economy to a larger extent. In present study, agricultural and meteorological drought in Maharashtra state was monitored using traditional as well as remote sensing methods. The meteorological drought assessment and characterization is done using two standard meteorological drought indices viz. standard precipitation index (SPI) and effective drought index (EDI). The severity and persistency of meteorological drought were studied using SPI for the period 1901 to 2015. However, accuracy of SPI in detection of sub-monthly drought is limited. Therefore, sub-monthly drought is effectively monitored using EDI. The monthly and sub-monthly drought mapped using SPI and EDI, respectively were then compared and assessed. It was concluded that EDI serves as a better indicator to monitor sub-monthly droughts. The agricultural drought monitoring was carried out using the remote sensing based indices such as vegetation condition index (VCI), temperature condition index (TCI), vegetation health index (VHI), shortwave angle slope index (SASI) and the index which maps the agricultural drought in a better way was identified. The area under drought as calculated by various agricultural drought indices compared with that of the EDI, it was found that the results of SASI matched with results of EDI. SASI denotes different values for the dry and wet soil and for the healthy and sparse vegetation. SASI monitors the agricultural drought better as compared to other indices used in this study

Unraveling the cytotoxic potential of Temozolomide loaded into PLGA nanoparticles

BACKGROUND: Nanotechnology has received great attention since a decade for the treatment of different varieties of cancer. However, there is a limited data available on the cytotoxic potential of Temozolomide (TMZ) formulations. In the current research work, an attempt has been made to understand the anti-metastatic effect of the drug after loading into PLGA nanoparticles against C6 glioma cells. Nanoparticles were prepared using solvent diffusion method and were characterized for size and morphology. Diffusion of the drug from the nanoparticles was studied by dialysis method. The designed nanoparticles were also assessed for cellular uptake using confocal microscopy and flow cytometry. RESULTS: PLGA nanoparticles caused a sustained release of the drug and showed a higher cellular uptake. The drug formulations also affected the cellular proliferation and motility. CONCLUSION: PLGA coated nanoparticles prolong the activity of the loaded drug while retaining the anti-metastatic activity

Farmer-led innovations: Best practices and lessons learnt in livestock rearing

The livestock sector contributes 4.11% in overall GDP, however, its full potential has not been utilized, necessitating need of innovations and the use of best practices for sustainable and profitable production. Farmers are a rich source of indigenous knowledge and they innovate, experiment and adapt continuously. Documentation of these success stories may serve as a lightening conductor for other farmers. The study was carried out with 35 progressive farmers from 10 agro-climatic regions of Karnataka. The study found that stall feeding for sheep, silage preparation and storage in bunkers, low cost dairy shed and locally made milking machine were innovations made by farmers. New technology adopted by the farmers included improved crossbreeds of sheep, emu farming, high tech dairy unit and fast growing breeds of pig. Farmers frequently used literature and KVK personnel as a source of information. Development of marketing linkages, direct marketing and contract farming were important aspects in post production operations. Farmers used some of the best practices like integrated farming system; clean and hygienic methods of milking, regular vaccinations, daily chart of feed, silage and bunker storage, rotation period, use of high jet water spray for washing of animal etc. Study concluded that qualities and traits like ability to select and integrate enterprise wisely; knowing and judging market demand correctly; developing market linkages; constant seeking of information and practical intelligence to use locally available resources were the key to success of dairy farmers. Dairy extension should play a pivotal role in imparting training to farmers about these aspects and spreading the success of these innovative farmers through literature in other parts of the country for its replication on large scale