131 research outputs found
Marine Delay and Disruption Tolerant Networks (MaDTN): Application for Artisanal Fisheries
The artisanal fishing activity carried out on the coasts where the production of fish can be exploited is affected by a lack of communication between the vessels in order to provide relevant information related to multiple marine sensor parameters. It is mainly due to the rugged geographic area that causes highly disruptive communication links and in which traditional IP-based communications with transport protocols such as TCP or UDP do not work properly. This paper presents and evaluates a new communications architecture to provide services to marine sensor networks using a disruption tolerant networking (DTN) based solution. We propose a new architecture that takes into account the different vessels densities. We assume a finite sensor population model and a saturated traffic condition where every sensor always has frames to transmit. The performance was evaluated in terms of delivery probabilities, delay and a DTN scenario indicator (DSI) proposed. Through simulations, this paper reveals that Low Density scenery yield greater latency, and more density of nodes has better results. We achieved a successful delivery rate of 74% and a latency of 2 h approximately. Finally indicators shows that high density of nodes is strongly recommended for fishery scenery models
Pharmacology and Therapeutic Potential of Sigma1 Receptor Ligands
Sigma (σ) receptors, initially described as a subtype of opioid receptors, are now considered unique receptors. Pharmacological studies have distinguished two types of σ receptors, termed σ1 and σ2. Of these two subtypes, the σ1 receptor has been cloned in humans and rodents, and its amino acid sequence shows no homology with other mammalian proteins. Several psychoactive drugs show high to moderate affinity for σ1 receptors, including the antipsychotic haloperidol, the antidepressant drugs fluvoxamine and sertraline, and the psychostimulants cocaine and methamphetamine; in addition, the anticonvulsant drug phenytoin allosterically modulates σ1 receptors. Certain neurosteroids are known to interact with σ1 receptors, and have been proposed to be their endogenous ligands. These receptors are located in the plasma membrane and in subcellular membranes, particularly in the endoplasmic reticulum, where they play a modulatory role in intracellular Ca2+ signaling. Sigma1 receptors also play a modulatory role in the activity of some ion channels and in several neurotransmitter systems, mainly in glutamatergic neurotransmission. In accordance with their widespread modulatory role, σ1 receptor ligands have been proposed to be useful in several therapeutic fields such as amnesic and cognitive deficits, depression and anxiety, schizophrenia, analgesia, and against some effects of drugs of abuse (such as cocaine and methamphetamine). In this review we provide an overview of the present knowledge of σ1 receptors, focussing on σ1 ligand neuropharmacology and the role of σ1 receptors in behavioral animal studies, which have contributed greatly to the potential therapeutic applications of σ1 ligands
On Exactness Of The Supersymmetric WKB Approximation Scheme
Exactness of the lowest order supersymmetric WKB (SWKB) quantization
condition , for certain
potentials, is examined, using complex integration technique. Comparison of the
above scheme with a similar, but {\it exact} quantization condition, , originating from the quantum Hamilton-Jacobi
formalism reveals that, the locations and the residues of the poles that
contribute to these integrals match identically, for both of these cases. As
these poles completely determine the eigenvalues in these two cases, the
exactness of the SWKB for these potentials is accounted for. Three non-exact
cases are also analysed; the origin of this non-exactness is shown to be due
the presence of additional singularities in , like branch
cuts in the plane.Comment: 11 pages, latex, 1 figure available on reques
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