Friction effects on quasi-steady dam-break wave propagation on horizontal beds

The propagation of dam-break waves on different rough beds was observed to be quasi-steady in the range < [CDATA[11.3 < x/h dam, where is measured from the dam position. These quasi-steady propagation speeds converge with the steady ideal fluids model of Stoker (Water Waves, 1957, Interscience) when the tailwater depth becomes greater than, in the range <[CDATA[0.001< k_s/h_{dam}, where is the roughness and the depth behind the dam. Hence, this convergence encourages the use of Stoker's steady, ideal fluid solution to develop more general models, including friction effects due to bed roughness and/or viscosity. The new experimental data support a MacLaurin series for the celerity, in analogy with the series in terms of, derived for Stoker's model, being the tailwater depth. Compared with the retarding effect of the tailwater, 1 mm of roughness is found to be equivalent to 13 mm of tailwater, and 1 m of viscous length (, where is the kinematic viscosity and g the acceleration due to gravity) is equivalent to 1700 m of tailwater. While the MacLaurin series quantifies the similar effects of small roughness and small tailwater depths acting separately, the new data illustrate for the first time the complex interplay between tailwater and roughness on 'wet beds' with many details yet to be investigated. In particular, it was shown that a small amount of tailwater on a rough bed acts as a lubricant, so that is an increasing function of for <[CDATA[h 2. Hydraulic Structures and Flood Ris

Characterization and feasibility studies on complete recovery of rare earths from glass polishing waste

One of the main applications of ceria (CeO 2 ) is its use in glass polishing. About 16,000 tonnes of rare earth oxides, which is about 10% of total rare earth production, are used for polishing applications. The waste generated in glass polishing contains rare earths, along with other impurities. In this study, two different glass polishing waste samples were characterized and two different processes were proposed for the complete recovery of rare earths from polishing waste, i.e., an acid-based process and an alkali-based process. The polishing waste samples were characterized with inductively coupled plasma optical emission spectrometry (ICP-OES), X-ray fluorescence spectroscopy (XRF), X-ray diffraction (XRD), scanning electron microscopy (SEM), thermo-gravimetric analysis (TGA) and particle size analysis. Chemical analysis showed that sample A (CeO 2 -rich waste from plate glass polishing) contained a high amount of impurities compared to sample B (CeO 2 -rich waste from mirror polishing). XRD analysis showed that sample B contained CeO 2 , LaO 0.65 F 1.7 and LaPO 4 compounds, whereas sample A contained CaCO 3 in addition to rare earth compounds. SEM-EDX analysis showed the presence of alumino-silicates in sample A. Leaching experiments were carried out at 75 ◦ C at different acid concentrations for the recovery of rare earths from polishing waste samples. The leaching results showed that it is difficult to dissolve rare earths completely in acid solutions due to the presence of fluorides and phosphates. Hence, undissolved rare earths in the leach residue were further recovered by an alkali treatment with NaOH. In another approach, polishing waste samples were directly treated with NaOH at 500 ◦ C. After alkali treatment followed by water leaching, rare earths can be completely dissolved during acid leaching. Rare earths from polishing waste can be recovered completely by both the acid-based process and the alkali-based process. (OLD) MSE-1Engineering Thermodynamics(OLD) MSE-

Recovery of rare earths from glass polishing waste for the production of aluminium-rare earth alloys

The circular economy demands waste utilization for the production of high-value products, and this requires the development of novel processing routes. In this study, rare earth (La and Ce) oxides were completely (>99%) recovered from polishing waste by a combined novel reductive acid leaching and alkali treatment process. About 70% of rare earths were dissolved during the first leaching step. The undissolved rare earth compounds are converted to oxides/hydroxides by alkali treatment and dissolved in the acid solution – the 2nd leaching step – for the complete recovery of rare earths. The recovered rare earth oxides were used for producing in-situ high-value Al-La-Ce alloys with fused salt electrolysis. Mechanical properties of our Al-La-Ce alloys are similar to the known high temperature Al-Ce alloys. This development of new alloys by our novel process helps in utilization of both overproduced primary La and Ce oxides as well as La and Ce recovered from polishing waste.Green Open Access added to TU Delft Institutional Repository 'You share, we take care!' - Taverne project https://www.openaccess.nl/en/you-share-we-take-care Otherwise as indicated in the copyright section: the publisher is the copyright holder of this work and the author uses the Dutch legislation to make this work public.(OLD) MSE-1Engineering ThermodynamicsTeam Yongxiang YangTeam Erik Offerma

Long-distance electron transport in individual, living cable bacteria

Electron transport within living cells is essential for energy conservation in all respiring and photosynthetic organisms. While a few bacteria transport electrons over micrometer distances to their surroundings, filaments of cable bacteria are hypothesized to conduct electric currents over centimeter distances. We used resonance Raman microscopy to analyze cytochrome redox states in living cable bacteria. Cable-bacteria filaments were placed in microscope chambers with sulfide as electron source and oxygen as electron sink at opposite ends. Along individual filaments a gradient in cytochrome redox potential was detected, which immediately broke down upon removal of oxygen or laser cutting of the filaments. Without access to oxygen, a rapid shift toward more reduced cytochromes was observed, as electrons were no longer drained from the filament but accumulated in the cellular cytochromes. These results provide direct evidence for long-distance electron transport in living multicellular bacteria.BT/Environmental Biotechnolog

Benchmark study of simulators for thermo-hydraulic modelling of low enthalpy geothermal processes

In order to assess the thermo-hydraulic modelling capabilities of various geothermal simulators, a comparative test suite was created, consisting of a set of cases designed with conditions relevant to the low-enthalpy range of geothermal operations within the European HEATSTORE research project. In an effort to increase confidence in the usage of each simulator, the suite was used as a benchmark by a set of 10 simulators of diverse origin, formulation, and licensing characteristics: COMSOL, MARTHE, ComPASS, Nexus-CSMP++, MOOSE, SEAWATv4, CODE_BRIGHT, Tough3, PFLOTRAN, and Eclipse 100. The synthetic test cases (TCs) consist of a transient pressure test verification (TC1), a well-test comparison (TC2), a thermal transport experiment validation (TC3), and a convection onset comparison (TC4), chosen to represent well-defined subsets of the coupled physical processes acting in subsurface geothermal operations. The results from the four test cases were compared among the participants, to known analytical solutions, and to experimental measurements where applicable, to establish them as reference expectations for future studies. A basic description, problem specification, and corresponding results are presented and discussed. Most participating simulators were able to perform most tests reliably at a level of accuracy that is considered sufficient for application to modelling tasks in real geothermal projects. Significant relative deviations from the reference solutions occurred where strong, sudden (e.g. initial) gradients affected the accuracy of the numerical discretization, but also due to sub-optimal model setup caused by simulator limitations (e.g. providing an equation of state for water properties).Geo-engineeringWater Resource

Identification of genetic variants associated with Huntington's disease progression: a genome-wide association study

Background Huntington's disease is caused by a CAG repeat expansion in the huntingtin gene, HTT. Age at onset has been used as a quantitative phenotype in genetic analysis looking for Huntington's disease modifiers, but is hard to define and not always available. Therefore, we aimed to generate a novel measure of disease progression and to identify genetic markers associated with this progression measure. Methods We generated a progression score on the basis of principal component analysis of prospectively acquired longitudinal changes in motor, cognitive, and imaging measures in the 218 indivduals in the TRACK-HD cohort of Huntington's disease gene mutation carriers (data collected 2008–11). We generated a parallel progression score using data from 1773 previously genotyped participants from the European Huntington's Disease Network REGISTRY study of Huntington's disease mutation carriers (data collected 2003–13). We did a genome-wide association analyses in terms of progression for 216 TRACK-HD participants and 1773 REGISTRY participants, then a meta-analysis of these results was undertaken. Findings Longitudinal motor, cognitive, and imaging scores were correlated with each other in TRACK-HD participants, justifying use of a single, cross-domain measure of disease progression in both studies. The TRACK-HD and REGISTRY progression measures were correlated with each other (r=0·674), and with age at onset (TRACK-HD, r=0·315; REGISTRY, r=0·234). The meta-analysis of progression in TRACK-HD and REGISTRY gave a genome-wide significant signal (p=1·12 × 10−10) on chromosome 5 spanning three genes: MSH3, DHFR, and MTRNR2L2. The genes in this locus were associated with progression in TRACK-HD (MSH3 p=2·94 × 10−8 DHFR p=8·37 × 10−7 MTRNR2L2 p=2·15 × 10−9) and to a lesser extent in REGISTRY (MSH3 p=9·36 × 10−4 DHFR p=8·45 × 10−4 MTRNR2L2 p=1·20 × 10−3). The lead single nucleotide polymorphism (SNP) in TRACK-HD (rs557874766) was genome-wide significant in the meta-analysis (p=1·58 × 10−8), and encodes an aminoacid change (Pro67Ala) in MSH3. In TRACK-HD, each copy of the minor allele at this SNP was associated with a 0·4 units per year (95% CI 0·16–0·66) reduction in the rate of change of the Unified Huntington's Disease Rating Scale (UHDRS) Total Motor Score, and a reduction of 0·12 units per year (95% CI 0·06–0·18) in the rate of change of UHDRS Total Functional Capacity score. These associations remained significant after adjusting for age of onset. Interpretation The multidomain progression measure in TRACK-HD was associated with a functional variant that was genome-wide significant in our meta-analysis. The association in only 216 participants implies that the progression measure is a sensitive reflection of disease burden, that the effect size at this locus is large, or both. Knockout of Msh3 reduces somatic expansion in Huntington's disease mouse models, suggesting this mechanism as an area for future therapeutic investigation