2,225 research outputs found
Electrical Compartmentalization in Neurons
The dendritic tree of neurons plays an important role in information processing in the brain. While it is thought that dendrites require independent subunits to perform most of their computations, it is still not understood how they compartmentalize into functional subunits. Here, we show how these subunits can be deduced from the properties of dendrites. We devised a formalism that links the dendritic arborization to an impedance-based tree graph and show how the topology of this graph reveals independent subunits. This analysis reveals that cooperativity between synapses decreases slowly with increasing electrical separation and thus that few independent subunits coexist. We nevertheless find that balanced inputs or shunting inhibition can modify this topology and increase the number and size of the subunits in a context-dependent manner. We also find that this dynamic recompartmentalization can enable branch-specific learning of stimulus features. Analysis of dendritic patch-clamp recording experiments confirmed our theoretical predictions.Peer reviewe
Unsolvability of the Halting Problem in Quantum Dynamics
It is shown that the halting problem cannot be solved consistently in both
the Schrodinger and Heisenberg pictures of quantum dynamics. The existence of
the halting machine, which is assumed from quantum theory, leads into a
contradiction when we consider the case when the observer's reference frame is
the system that is to be evolved in both pictures. We then show that in order
to include the evolution of observer's reference frame in a physically sensible
way, the Heisenberg picture with time going backwards yields a correct
description.Comment: 4 pages, 3 figure
BioConcens: Biomass and bioenergy production agriculture – consequences for soil fertility, environment, spread of animal parasites and socio-economy
The research programme called “international research cooperation and organic integrity” was commenced for a period 2006-2010. It is coordinated by DARCOF (The Danish Research Centre for Organic Farming). The whole programme, with acronym DARCOF III, consists of 15 projects (http://www.darcof.dk/research/darcofiii/index.html). One of them is BIOCONCENS - Biomass and bioenergy production in organic farming – consequences for soil fertility, environment, spread of animal parasites and socio-economy (http://www.bioconcens.elr.dk/uk/). The production of bioenergy in organic agriculture (OA) can reduce its dependency of fossil fuels and decrease green house gasses emission; consequently it will increase sustainability of organic farms. Biorefinery concept based on co-production of biogas, bioethanol and protein fodder in organic farming will be developed within the BIOCONCENS project and the background for the project and the different work packages will be presented in this paper
Frontotemporal Dementia Caused by CHMP2B Mutations
CHMP2B mutations are a rare cause of autosomal dominant frontotemporal dementia (FTD). The best studied example is frontotemporal dementia linked to chromosome 3 (FTD-3) which occurs in a large Danish family, with a further CHMP2B mutation identified in an unrelated Belgian familial FTD patient. These mutations lead to C-terminal truncations of the CHMP2B protein and we will review recent advances in our understanding of the molecular effects of these mutant truncated proteins on vesicular fusion events within the endosome-lysosome and autophagy degradation pathways. We will also review the clinical features of FTD caused by CHMP2B truncation mutations as well as new brain imaging and neuropathological findings. Finally, we collate the current data on CHMP2B missense mutations, which have been reported in FTD and motor neuron disease
Quantum theory as a relevant framework for the statement of probabilistic and many-valued logic
Based on ideas of quantum theory of open systems we propose the consistent
approach to the formulation of logic of plausible propositions. To this end we
associate with every plausible proposition diagonal matrix of its likelihood
and examine it as density matrix of relevant quantum system. We are showing
that all logical connectives between plausible propositions can be represented
as special positive valued transformations of these matrices. We demonstrate
also the above transformations can be realized in relevant composite quantum
systems by quantum engineering methods. The approach proposed allows one not
only to reproduce and generalize results of well-known logical systems
(Boolean, Lukasiewicz and so on) but also to classify and analyze from unified
point of view various actual problems in psychophysics and social sciences.Comment: 7 page
Optimal estimation of quantum dynamics
We construct the optimal strategy for the estimation of an unknown unitary
transformation . This includes, in addition to a convenient
measurement on a probe system, finding which is the best initial state on which
is to act. When , such an optimal strategy can be applied to
estimate simultaneously both the direction and the strength of a magnetic
field, and shows how to use a spin 1/2 particle to transmit information about a
whole coordinate system instead of only a direction in space.Comment: 4 pages, REVTE
Optimal correction of concatenated fault-tolerant quantum codes
We present a method of concatenated quantum error correction in which
improved classical processing is used with existing quantum codes and
fault-tolerant circuits to more reliably correct errors. Rather than correcting
each level of a concatenated code independently, our method uses information
about the likelihood of errors having occurred at lower levels to maximize the
probability of correctly interpreting error syndromes. Results of simulations
of our method applied to the [[4,1,2]] subsystem code indicate that it can
correct a number of discrete errors up to half of the distance of the
concatenated code, which is optimal.Comment: 7 pages, 2 figures, published versio
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