7,448 research outputs found

    Double jeopardy: hypoglycaemia and advanced hepatocellular carcinoma

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    Nonislet cell tumour-induced hypoglycaemia is an uncommon, but serious complication of malignancy. The aetiopathogenesis is largely as a result of tumoral overproduction of incompletely processed insulin-like growth factor-II. We describe the case of a 30-year-old black male patient who presented with recurrent hypoglycaemic episodes in the absence of diabetes or any medications known to cause hypoglycaemia. Extensive investigations revealed that the hypoglycaemia was the result of an advanced hepatocellular carcinoma.Keywords: hypoglycaemia, non-islet cell tumour-induced hypoglycaemia, insulin-like growth factor-II, hepatocellular carcinom

    Micro-CernVM: Slashing the Cost of Building and Deploying Virtual Machines

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    The traditional virtual machine building and and deployment process is centered around the virtual machine hard disk image. The packages comprising the VM operating system are carefully selected, hard disk images are built for a variety of different hypervisors, and images have to be distributed and decompressed in order to instantiate a virtual machine. Within the HEP community, the CernVM File System has been established in order to decouple the distribution from the experiment software from the building and distribution of the VM hard disk images. We show how to get rid of such pre-built hard disk images altogether. Due to the high requirements on POSIX compliance imposed by HEP application software, CernVM-FS can also be used to host and boot a Linux operating system. This allows the use of a tiny bootable CD image that comprises only a Linux kernel while the rest of the operating system is provided on demand by CernVM-FS. This approach speeds up the initial instantiation time and reduces virtual machine image sizes by an order of magnitude. Furthermore, security updates can be distributed instantaneously through CernVM-FS. By leveraging the fact that CernVM-FS is a versioning file system, a historic analysis environment can be easily re-spawned by selecting the corresponding CernVM-FS file system snapshot.Comment: Conference paper at the 2013 Computing in High Energy Physics (CHEP) Conference, Amsterda

    Angle-resolved photoemission study of the role of nesting and orbital orderings in the antiferromagnetic phase of BaFe2As2

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    We present a detailed comparison of the electronic structure of BaFe2As2 in its paramagnetic and antiferromagnetic (AFM) phases, through angle-resolved photoemission studies. Using different experimental geometries, we resolve the full elliptic shape of the electron pockets, including parts of dxy symmetry along its major axis that are usually missing. This allows us to define precisely how the hole and electron pockets are nested and how the different orbitals evolve at the transition. We conclude that the imperfect nesting between hole and electron pockets explains rather well the formation of gaps and residual metallic droplets in the AFM phase, provided the relative parity of the different bands is taken into account. Beyond this nesting picture, we observe shifts and splittings of numerous bands at the transition. We show that the splittings are surface sensitive and probably not a reliable signature of the magnetic order. On the other hand, the shifts indicate a significant redistribution of the orbital occupations at the transition, especially within the dxz/dyz system, which we discuss

    Resonant inelastic x-ray scattering probes the electron-phonon coupling in the spin-liquid kappa-(BEDT-TTF)2Cu2(CN)3

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    Resonant inelastic x-ray scattering at the N K edge reveals clearly resolved harmonics of the anion plane vibrations in the kappa-(BEDT-TTF)2Cu2(CN)3 spin-liquid insulator. Tuning the incoming light energy at the K edge of two distinct N sites permits to excite different sets of phonon modes. Cyanide CN stretching mode is selected at the edge of the ordered N sites which are more strongly connected to the BEDT-TTF molecules, while positionally disordered N sites show multi-mode excitation. Combining measurements with calculations on an anion plane cluster permits to estimate the sitedependent electron-phonon coupling of the modes related to nitrogen excitation

    How can we reduce the risk of mother-to-child transmission of HIV during invasive obstetric procedures?

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    Antenatal invasive obstetric procedures may be diagnostic or therapeutic, and are performed at different stages of pregnancy for various indications. The most common indication for an invasive procedure during pregnancy is for fetal karyotyping when a chromosomal abnormality or a genetic defect is suspected, either from the couple’s history or from ultrasound assessment of the fetus. Other less common but equally important indications may be diagnostic (fetoscopy, fetal tissue sampling, estimation of fetal haemoglobin) or therapeutic (aspiration of various fetal cavities, fetal blood transfusion and embryo reductions). In a high HIV prevalence setting like South Africa, a significant proportion of pregnant women in need of invasive procedures will be HIV-infected
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