[Massive metachronous inguinal metastases of carcinoma of the anal margin. A clinical case report].

The authors report a case of epidermoid carcinoma of the anal margin with repeated metachronous metastases in the inguinal lymph nodes. The treatment of synchronous ad metachronous metastases is briefly discussed through a literature review

Early gastric cancer

A clear difference in survival among the patients affected by gastric cancer has been observed worldwide between Early Gastric Cancer (EGC) and Advanced Gastric Cancer (AGC). Optical fiber endoscopy has allowed a sharp increase in the number of diagnoses of EGC since the sixties. Among 182 patients operated on, 19 [10.4%] had an EGC. A difference in incidence was found between males and females, while no difference was found in the age distribution. The main symptom was epigastric pain; EGCS common findings were ulceration or a flat tumor. Surgical procedures were carried out with the same criteria used for AGC. No difference was found in the tumor location. Local spread was studied according to the Japanese Research Society for Gastric Cancer, while histological type was classified according to Lauren classification. Crude 5-year survival was 80% (8 out of 10), with a mean of 76.8 ± 13 (SEM) months

Therapeutic approaches to patients with pilonidal sinus based on specific clinical characteristics

Controversies exist about the optimal treatment for patients with pilonidal disease. Our therapeutic approach to patients with this condition has been conservative treatment. Surgery was performed only after failure of conservative treatment. Surgery consisted of excision of the sinus and primary closure in patients of female sex and with sinus of small dimensions. Excision and Limberg flap was performed in male patients with a large sinus. Conservative treatment was successful in almost 50% of the patients. Excision and Limberg flap reconstruction had fewer recurrences than excision and primary closure; however, patients were less satisfied from an aesthetic point of view. Therapeutic approach to patients with pilonidal sinus should be modified according to the clinical conditions of the patient and anatomic characteristics of sinus. © 2011 Springer-Verlag

FIBROMATOSI MESENTERICA ISOLATA. CASO CLINICO

The authors report a case of isolated mesenteric fibromatosis un associated with familial adenomatous polyposis or Gardner's syndrome or prior abdominal surgery. These neoplasms are usually asymptomatic until when the compression of the small or large bowel or the ureter causes symptoms; although they are benign lesions without metastases, local recurrences are very frequent. Surgical removal is the primary treatment; until now no satisfactory results have been obtained with other therapeutic modalitie

ASSOCIATION ANEVRISMES ARTERIELS MULTIPLES ET MALADIE KYSTIQUE HEPATO-RENALE

BACKGROUND: Ehlers Danlos syndrome (type IV) and kidney and liver cyst disease can present a common factor: anomalous biosynthesis of structural collagen and elastic tissue. We present an exceptional case. CASE REPORT: A 62-year-old man complained of pain in the upper left quadrant of the abdomen. Ultrasonography, magnetic resonance imaging and arteriography evidenced an aneurysm of the splenic artery, an aneurysm of the hypogastric artery, multiple cysts in the kidney and liver, and mitral valvulopathy. Treatment was splenectomy with resection of the splenic aneurysm and resection of the iliac aneurysm and iliac-iliac bypass. DISCUSSION: The association of kidney and liver cyst disease with venous gastrointestinal and cardiovascular complications is well known. The simultaneous presence of cysts and peripheral and visceral aneurysms with anomalies of the arterial wall resembling Ehlers Danlos syndrome (type IV) would suggest that these two diseases might result from a common connective tissue anomaly. The underlying mechanism(s) remain unknown

[Malignant nodular hidradenoma. A clinical case].

Malignant clear cell hidradenoma is an uncommon tumor of eccrine sweat gland origin. In contrast to the benign form, malignant clear cell hidradenoma tends to invade the surrounding tissue and has a high incidence of distant metastases. For these reasons a wide surgical excision associated to a locoregional lymph node dissection should be performed alter the initial diagnosis. The case of a 17 year old female with this rare lesion is reported; the literature is reviewed and surgical treatment discussed