Obesidad visceral, razón masa grasa/masa muscular y dislipidemia aterogénica: estudio transversal realizado en Riobamba, Ecuador

Introduction: The distribution and composition of fat mass is associated with different metabolic risks. The predominance of brown visceral fat is associated with risk factors for cardiovascular disease (CVD), such as: high triglycerides and apolipoprotein B, increased LDL cholesterol, ratio triglycerides/low HDL cholesterol elevated (atherogenic dyslipidemia indicator), insulin resistance, hyperinsulinemia and cardiovascular risk (CVR). Sarcopenia and obesity may act synergistically in functional and metabolic disorders. The aim of this study was to determine the relationship between visceral obesity, fat mass/muscular mass ratio and atherogenic dyslipidemia in adult individuals in order to determine the association pattern between these variables and set strategies for focused attention.Material and Methods: In a sample of 307 subjects of both sexes (21-71 years) there was measured atherogenic dyslipidemia as the ratio of triglyceride/HDL cholesterol, visceral obesity measured by bio impedance as the relative score of visceral fat, and the ratio fat mass/lean mass.Results: A cluster analysis was performed to establish the structure of association between these variables with different risk groups. Three groups were identified: the first had visceral obesity with an average relative level of visceral fat of 13.6, the second group with an average of 8.9 and in the third group were placed individuals with the lowest visceral obesity score averaging 6.5. As for the fat mass/lean mas ratio the first two groups had a similar average of this index with a value of 1.56 and 1.69 respectively and the third group with the lowest average value of 1.3. Group 1 presented visceral obesity and impaired fat mass/lean mass ratio and had a high value of triglyceride/HDL ratio 4.1. Group 2 without visceral obesity and a deterioration in the relative fat mass/lean mass ratio had a triglyceride/HDL cholesterol of 3.6 and Group 3; not recorded visceral obesity or impaired fat mass/lean mass ratio had the lowest triglycerides/lower HDL ratio: 1.9.Conclusions: It can be said that visceral obesity and the decrease in lean mass relative or absolute in relation to fat mass represents a high cardiovascular risk associated with atherogenic dyslipidemia, insulin resistance and cardiovascular risk.Introducción: La distribución y composición de la masa grasa representa diferentes riesgos metabólicos. La grasa visceral de predominio parda se asocia con factores de riesgo de enfermedad cardiovascular (ECV), como son: concentraciones elevadas de triglicéridos y apolipoproteína B, mayor colesterol LDL, una relación triglicéridos elevados/colesterol HDL bajo (indicador de dislipidemia aterogénica), resistencia a la insulina, hiperinsulinemia y riesgo cardiovascular (RCV). La sarcopenia y la obesidad pueden actuar de manera sinérgica en los trastornos funcionales y metabólicos. El objetivo de este estudio fue determinar la relación entre obesidad visceral, relación masa grasa/masa muscular y dislipidemia aterogénica en individuos adultos con la finalidad de conocer los patrones de asociación entre estas variables y establecer estrategias de atención focalizadas.Material y Métodos: En una muestra de 307 sujetos de ambos sexos (21-71 años) se midió dislipidemia aterogénica como la relación de triglicéridos/HDL, la obesidad visceral por bioimpedancia como el puntaje relativo de grasa visceral y la relación masa grasa/masa magra.Resultados: Se realizó un análisis de conglomerados para establecer la estructura de asociación de las variables estudiadas con diferentes grupos de riesgo; así se identificaron 3 grupos: el primero con presencia de obesidad visceral con un promedio de nivel relativo de grasa visceral de 13,6, el segundo grupo con un promedio de 8,9 y en el tercer grupo se ubicaron individuos sin obesidad visceral con un promedio de 6,5 de este valor relativo. En cuanto a la relación masa grasa y masa magra los dos primeros grupos presentaron un promedio similar de este índice con un valor de 1,56 y 1,69 respectivamente y el tercer grupo con un valor promedio de 1,3. El grupo 1 que presentó obesidad visceral y deterioro de la razón masa grasa/masa magra tuvo un valor elevado de la razón triglicéridos/colesterol HDL: 4,1. El grupo 2 sin obesidad visceral y con un deterioro de la relación masa grasa/masa magra tuvo una razón triglicéridos/colesterol HDL de 3,6 y grupo 3 que no registró ni obesidad ni deterioro de la razón masa grasa/masa magra tuvo la razón triglicéridos/colesterol HDL más baja: 1,9.Conclusiones: Se puede decir que la obesidad visceral unida a la disminución de la masa magra relativa o absoluta en relación con la masa grasa representa un alto riesgo por asociarse con dislipidemia aterogénica, resistencia a la insulina y riesgo cardiovascular

Sleep quality does not mediate the negative effects of chronodisruption on body composition and metabolic syndrome in healthcare workers in Ecuador

Background and aims: The objective of the present work was to determine to what extent sleep quality may mediate the association between chronodisruption (CD) and metabolic syndrome (MS), and between CD and body composition (BC). Methodology: Cross-sectional study which included 300 adult health workers, 150 of whom were night shift workers and thereby exposed to CD. Diagnosis of MS was made based on Adult Treatment Panel III criteria. Sleep quality was measured using the Pittsburgh Sleep Quality Index. Body mass index (BMI), fat mass percentage, and visceral fat percentage were mea

Sleep quality does not mediate the negative effects of chronodisruption on body composition and metabolic syndrome in healthcare workers in Ecuador

BACKGROUND AND AIMS: The objective of the present work was to determine to what extent sleep quality may mediate the association between chronodisruption (CD) and metabolic syndrome (MS), and between CD and body composition (BC). METHODOLOGY: Cross-sectional study which included 300 adult health workers, 150 of whom were night shift workers and thereby exposed to CD. Diagnosis of MS was made based on Adult Treatment Panel III criteria. Sleep quality was measured using the Pittsburgh Sleep Quality Index. Body mass index (BMI), fat mass percentage, and visceral fat percentage were measured as indicators of body composition (BC). Data were analyzed using logistic, linear regression and structural equation models. RESULTS: The odds of health workers exposed to CD to suffer MS was 22.13 (IC95 8.68-66.07) when the model was adjusted for age, gender, physical activity and energy consumption. CD was also significantly associated with an increase in fat mass and visceral fat percentages, but not to BMI. Surprisingly, there was not enough evidence supporting the hypothesis that sleep quality contributes to the association between CD and MS or between CD and BC. CONCLUSIONS: Sleep quality does not mediate the negative effects of CD on MS nor on BC