Hidden Markov Model Identifiability via Tensors

The prevalence of hidden Markov models (HMMs) in various applications of statistical signal processing and communications is a testament to the power and flexibility of the model. In this paper, we link the identifiability problem with tensor decomposition, in particular, the Canonical Polyadic decomposition. Using recent results in deriving uniqueness conditions for tensor decomposition, we are able to provide a necessary and sufficient condition for the identification of the parameters of discrete time finite alphabet HMMs. This result resolves a long standing open problem regarding the derivation of a necessary and sufficient condition for uniquely identifying an HMM. We then further extend recent preliminary work on the identification of HMMs with multiple observers by deriving necessary and sufficient conditions for identifiability in this setting.Comment: Accepted to ISIT 2013. 5 pages, no figure

Impact of climate policy uncertainty on return spillover among green assets and portfolio implications

Peer reviewe

Does the U.S. export inflation? Evidence from the dynamic inflation spillover between the U.S. and EAGLEs

Peer reviewe

Vimentin is a novel AKT1 target mediating motility and invasion.

The PI3K/AKT signaling pathway is aberrant in a wide variety of cancers. Downstream effectors of AKT are involved in survival, growth and metabolic-related pathways. In contrast, contradictory data relating to AKT effects on cell motility and invasion, crucial prometastatic processes, have been reported pointing to a potential cell type and isoform type-specific AKT-driven function. By implication, study of AKT signaling should optimally be conducted in an appropriate intracellular environment. Prognosis in soft-tissue sarcoma (STS), the aggressive malignancies of mesenchymal origin, is poor, reflecting our modest ability to control metastasis, an effort hampered by lack of insight into molecular mechanisms driving STS progression and dissemination. We examined the impact of the cancer progression-relevant AKT pathway on the mesenchymal tumor cell internal milieu. We demonstrate that AKT1 activation induces STS cell motility and invasiveness at least partially through a novel interaction with the intermediate filament vimentin (Vim). The binding of AKT (tail region) to Vim (head region) results in Vim Ser39 phosphorylation enhancing the ability of Vim to induce motility and invasion while protecting Vim from caspase-induced proteolysis. Moreover, vimentin phosphorylation was shown to enhance tumor and metastasis growth in vivo. Insights into this mesenchymal-related molecular mechanism may facilitate the development of critically lacking therapeutic options for these devastating malignancies

Deux applications de processus ponctuels aux réseaux de communication

- Cet article résume des résultats récents obtenus en utilisant des processus ponctuels (plus précisémment, des bruits impulsionnels) pour deux applications dans le contexte des réseaux de communication: d'une part, la modélisation du trafic TCP/IP dans les réseaux d'épine dorsale, et d'autre part les propriétés de connectivité des réseaux ad hoc sans fil sous des contraintes de débit