29 research outputs found

    Holographic Flavor Transport in Arbitrary Constant Background Fields

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    We use gauge-gravity duality to compute a new transport coefficient associated with a number Nf of massive N=2 supersymmetric hypermultiplet fields propagating through an N=4 SU(Nc) super-Yang-Mills theory plasma in the limits of large Nc and large 't Hooft coupling, with Nf << Nc. We introduce a baryon number density as well as arbitrary constant electric and magnetic fields, generalizing previous calculations by including a magnetic field with a component parallel to the electric field. We can thus compute all components of the conductivity tensor associated with transport of baryon number charge, including a component never before calculated in gauge-gravity duality. We also compute the contribution that the flavor degrees of freedom make to the stress-energy tensor, which exhibits divergences associated with the rates of energy and momentum loss of the flavor degrees of freedom. We discuss two currents that are free from these divergences, one of which becomes anomalous when the magnetic field has a component parallel to the electric field and hence may be related to recent study of charge transport in the presence of anomalies.Comment: 27 page

    Fibulin-3 is necessary to prevent cardiac rupture following myocardial infarction

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    Published online: 11 September 2023Despite the high prevalence of heart failure in the western world, there are few effective treatments. Fibulin-3 is a protein involved in extracellular matrix (ECM) structural integrity, however its role in the heart is unknown. We have demonstrated, using single cell RNA-seq, that fibulin-3 was highly expressed in quiescent murine cardiac fibroblasts, with expression highest prior to injury and late post-infarct (from ~ day-28 to week-8). In humans, fibulin-3 was upregulated in left ventricular tissue and plasma of heart failure patients. Fibulin-3 knockout (Efemp1-/-) and wildtype mice were subjected to experimental myocardial infarction. Fibulin-3 deletion resulted in significantly higher rate of cardiac rupture days 3-6 post-infarct, indicating a weak and poorly formed scar, with severe ventricular remodelling in surviving mice at day-28 post-infarct. Fibulin-3 knockout mice demonstrated less collagen deposition at day-3 post-infarct, with abnormal collagen fibre-alignment. RNA-seq on day-3 infarct tissue revealed upregulation of ECM degradation and inflammatory genes, but downregulation of ECM assembly/structure/organisation genes in fibulin-3 knockout mice. GSEA pathway analysis showed enrichment of inflammatory pathways and a depletion of ECM organisation pathways. Fibulin-3 originates from cardiac fibroblasts, is upregulated in human heart failure, and is necessary for correct ECM organisation/structural integrity of fibrotic tissue to prevent cardiac rupture post-infarct.Lucy A. Murtha, Sean A. Hardy, Nishani S. Mabotuwana, Mark J. Bigland, Taleah Bailey, Kalyan Raguram, Saifei Liu, Doan T. Ngo, Aaron L. Sverdlov, Tamara Tomin, Ruth Birner, Gruenberger, Robert D. Hume, Siiri E. Iismaa, David T. Humphreys, Ralph Patrick, James J. H. Chong, Randall J. Lee, Richard P. Harvey, Robert M. Graham, Peter P. Rainer and Andrew J. Boyl

    Numerical modeling of thermally-induced fractures in a large rock salt mass

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    Numerical modeling of thermally-induced fractures is a concern for many geo-structures including deep underground energy storage caverns. In this paper, we present the numerical simulation of a large-scale cooling experiment performed in an underground rock salt mine. The theory of fracture mechanics was embedded in the extended finite element code used. The results provide reliable information on fracture location and fracture geometry. Moreover, the timing of the fracture onset, as well as the stress redistribution due to fracture propagation, is highlighted. The conclusions of this numerical approach can be used to improve the design of rock salt caverns in order to guarantee their integrity in terms of both their tightness and stability. Keywords: Fracture mechanics, Thermal loading, Extended finite element method (XFEM) simulation, Rock sal

    Quantitative measurements of phase using the transport of intensity equation

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    In this paper we present considerations for experimental recovery of electron phase using the TIE algorithm as applied to TEM images. Realistic simulations have considerably aided interpretation of results. Experimental reconstructions show that low spatial frequency artefacts in the phase reconstruction, resulting from very small variations in the detected signal, can be reduced by using images with smaller numbers of pixels

    Linearising pulsewidth modulator for three-phase boost inverter

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    Design And Fabrication Of Integrated Power Inductor Based On Silicon Molding Technology

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    This paper reports a new fabrication process that can be used to integrate high-power-density and low-loss inductors with silicon-based power ICs to realize monolithic integration of power converters for portable electronics applications. In this new process, copper is electroplated into through-wafer silicon trenches, resulting in thick copper windings (200-500 μm) and thus low winding resistance. The magnetic cores are electroplated on both sides of the silicon substrate to cover the copper windings, and through-wafer magnetic vias are used to close the magnetic path. Powder permalloy with relatively high resistivity (400 μΩω.cm) and low permeability (40) are used to reduce the loss of large magnetic cores. The powder permalloy can be fabricated by using high-current-density electroplating without mixing or high temperature sintering. A pot-core inductor has been designed and fabricated. The inductance and saturation current of the designed inductor are 179 nH and 5 A, respectively. The measured winding resistance of the 200 μm thick copper winding is 23 mω. © 2007 IEEE

    Comparative Investigation On Different Topologies Of Integrated Magnetic Structures For Current-Doubler Rectifier

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    The advancement of technology requires that power supplies have high efficiency and high power density. The current doubler rectifier has been presented as a solution to decrease the transformer secondary power loss and increase the power efficiency. In this paper, the unified equivalent coupled inductor circuit models are constructed for different current doubler rectifier integrated magnetic structures. Based on the finite element method analysis, the impedance matrixes and coupling coefficient matrixes of different structures are compared. The efficiency and performance of different structures are also experimentally studied. © 2007 IEEE

    A joint scheduling and power control scheme for hybrid I2V/V2V networks

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    In automotive infotainment systems, vehicles using the applications are serviced via continuous infrastructure-to-vehicle (I2V) communications. Additionally, the I2V communications can be combined with vehicle-to-vehicle (V2V) connectivity owing to the small area covered by road side units (RSUs). However, dozens of vehicles have to compete for limited bandwidth when they request service simultaneously in the covered area. In this paper, we propose a joint scheduling and power control scheme for I2V and V2V links in the RSUs' coverage range. Mapping the I2V and V2V links to tuple-links, we formulate a mixed-integer nonlinear programming (MINLP) problem where frequency scheduler and power controller for those tuple-links are jointly designed. Then, we employ the delayed column generation technique and the transmission pattern definition to decompose the MINLP problem into a transmission pattern scheduling problem, as well as a power control problem. Therein, the transmission pattern scheduling problem is solved by linear programming while a greedy power control algorithm is developed. Simulation results with practical parameter settings show that our proposed scheme outperforms several conventional schemes in terms of service disruption and achieved throughput while maintaining throughput fairness among the requesting vehicles. In particular, a high channel number, a small power level number, and a large buffer size at the requesting vehicles are shown to be helpful for our proposed scheme.Bach Long Nguyen, Duy Trong Ngo, Minh N. Dao, Quang-Thang Duong, and Minoru Okad
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