The Impact of Light Touch and Pin Prick on Functional Outcomes in Patients with Traumatic Spinal Cord Injury

A spinal cord injury (SCI) can cause severe lifelong functional disability and profoundly affect an individual’s daily life. We investigated the prediction of patients’ post-SCI functional outcomes by evaluating sensory scores rather than motor scores, as the latter’s association with functional outcomes is well established. We examined patients’ responses to a light touch (LT) and pin prick (PP) at admission and the response data’s usefulness as predictors of functional outcomes (i.e., ability to perform activities of daily living) at discharge. This exploratory observational study used data from the Japanese National Spinal Cord Injury Database (SCI-J). Data from 3,676 patients who met the inclusion criteria and were admitted for an SCI between 1997 and 2020 were analyzed. The motor score of the Functional Independence Measure (mFIM) at discharge was used as an index of functional outcome. A multiple regression analysis revealed that the mFIM was associated with both the LT response (β=0.07 (0.01), p<0.001) and the PP response (β=0.07 (0.01), p<0.001) at admission. The false discovery rate log-worth values for LT and PP were 6.6 and 8.5, respectively. Our findings demonstrate that LT and PP scores at admission can help predict patients’ functional outcomes after an SCI, although the magnitude of their contributions is not high

Misconceptions and Rumors about Ebola Virus Disease in Sub-Saharan Africa: A Systematic Review

We sought to summarize knowledge, misconceptions, beliefs, and practices about Ebola that might impede the control of Ebola outbreaks in Africa. We searched Medline, EMBASE, CINAHL, and Google Scholar (through May 2019) for publications reporting on knowledge, attitudes, and practices (KAP) related to Ebola in Africa. In total, 14 of 433 articles were included. Knowledge was evaluated in all 14 articles, and they all highlighted that there are misconceptions and risk behaviors during an Ebola outbreak. Some communities believed that Ebola spreads through the air, mosquito bites, malice from foreign doctors, witchcraft, and houseflies. Because patients believe that Ebola was caused by witchcraft, they sought help from traditional healers. Some people believed that Ebola could be prevented by bathing with salt or hot water. Burial practices where people touch Ebola-infected corpses were common, especially among Muslims. Discriminatory attitudes towards Ebola survivors or their families were also prevalent. Some Ebola survivors were not accepted back in their communities; the possibility of being ostracized from their neighborhoods was high and Ebola survivors had to lead a difficult social life. Most communities affected by Ebola need more comprehensive knowledge on Ebola. Efforts are needed to address misconceptions and risk behaviors surrounding Ebola for future outbreak preparedness in Africa

Respiratory problems of sands carriers in the city of Lubumbashi/Rd Congo

Objective: To determine the prevalence of respiratory symptoms and illustrate the dangerousness of the sands dust in the Artisanal carriers in the city of Lubumbashi, Katanga province, in the Democratic Republic of the Congo (DRC). Method: In total, 120 carriers of sand have been recruited in an exhaustive approach with 120 communal administrative officers of Lubumbashi city as control group. Respiratory symptoms were collected using a respiratory questionnaire. A multi-analysis varied with the test of logistic regression has been privileged to determine the association between the characteristics of the carriers and the respiratory symptoms. Results: The prevalence of respiratory symptoms reported in carriers of sands was greater than that of the control group for the symptoms such as: cough in the morning (52.5% against 6.7%), sputum in the morning (35% against 7.5%), shortness of breath after effort (18.3% against 5%), asthma (26.7% against 5%), chronic bronchitis (12.5% against 4.2%), rhinitis (62.5% against 21.7%), conjunctivitis (58.3% against 17.5%). After adjustment, on factors such as age and education, the profession carrier of sands was strongly associated with the risk of developing respiratory symptoms below: spit in the morning, shortness of breath after effort, asthma, chronic bronchitis with a p &lt; 0.001. The Peak Expiratory Flow Rate (PEFR) has been significantly reduced in the Carriers of sands (438.87 ± 109.02) compared to controls (480.14 ± 70.73) (p ˂ 0.05). Conclusion: The profession carriers of sand as practiced in Lubumbashi, without means of adequate protection

Rainstorm and Flood Disasters: Case study of Shelter Management by Manila Municipal DRR (Disaster Risk Reduction) Teams during Tropical Storm Mario (Fung Wong) in 2014

Floods are the leading cause of natural disaster-related deaths worldwide. This study aimed at assessing disaster preparedness and response by local Barangay (municipal) DRR (disaster risk reduction) teams during the flooding caused by tropical storm Mario in Manila in 2014. A cross-sectional and descriptive study was conducted, consisting of interviews in which five shelter managers participated. In total, 325 evacuees were received in 4 evacuation centers, whereas the remaining shelter received 30 families housed in tents. Only 3 shelters (60%) had some food and non-food items available prior to the arrival of evacuees. WASH (Water, sanitation and hygiene) services were insufficient; latrines were available in 4 (80%) shelters, but no latrine was available for displaced people housed in tents. Only 3 (60%) shelters had toilets cleaned regularly. Detergents, toothbrushes and toothpastes were provided in 3 (60 %) shelters, whereas only 2 (40%) had diapers for babies and none (0%) had hygienic period items for ladies. Food items were daily distributed in 3 (60%) shelters. Health services were not satisfactory, as medical consultations were organized but irregularly in 3 (60%) of the five shelters. Disaster preparedness and response in Barangay shelters were not satisfactory, suggesting the necessity for the central government to support local DRR volunteer teams. It is recommended to provide the volunteers with an inexpensive ICT (information and communications technology) tool to collect disaster preparedness data so that relief efforts will be more than sufficient at the time of disaster

Respiratory health of artisanal miner of Lwisha in Katanga/DR Congo

Objective: To determine the prevalence of respiratory symptoms and make an awareness about the harmful effects of ores dust in the Artisanal miner in the city of Lubumbashi, Katanga province, in the Democratic Republic of the Congo (DRC). Method: In total, 104 artisanal miners have been recruited in an exhaustive manner with 122 administrative officers in the town hall of Lubumbashi, responsible for collecting the taxes in the Stations of the bus as the control group. Respiratory symptoms were collected using a standardized questionnaire. To determine the association between the characteristics of the miners and respiratory symptoms reported, a multi-analysis combined with the test of logistic regression has been privileged. Results: The prevalence of the respiratory symptoms was markedly higher in the artisanal diggers, as compared with the group that controls: wheezing (37.5% vs. 7.4%), shortness breathing after effort (26.9% vs. 3.3%), cough (29.8% vs. 12.3%), asthma (24% vs. 1.6%), rhinitis (20.2% vs. 14.8%), conjunctivitis (16.3% vs. 9.8%), and eczema (34.6% vs. 2.5%). After adjusting for age and education level, digger as occupation was strongly associated with a higher risk of developing respiratory and skin problems (p &lt; 0.05). Conclusion: The study revealed that artisanal miner’s professions, as practiced in Lubumbashi, without any protection against dust, have a negative impact on the respiratory health. It proves to be very important to organize a teaching specialized in Occupational Medicine that can train some physicians with an established expertise having to answer if it is needed to be enormous in qualified staff in this area considered at respiratory risk

Local perspectives on Ebola during its tenth outbreak in DR Congo: A nationwide qualitative study

Background The Democratic Republic of Congo (DR Congo) struggled to end the tenth outbreak of Ebola virus disease (Ebola), which appeared in North Kivu in 2018. It was reported that rumors were hampering the response effort. We sought to identify any rumors that could have influenced outbreak containment and affected prevention in unaffected areas of DR Congo. Methods We conducted a qualitative study in DR Congo over a period of 2 months (from August 1 to September 30, 2019) using in-depth interviews (IDIs) and focus group discussions (FGDs). The participants were recruited from five regional blocks using purposeful sampling. Both areas currently undergoing outbreaks and presently unaffected areas were included. We collected participants’ opinions, views, and beliefs about the Ebola virus. The IDIs (n = 60) were performed with key influencers (schoolteachers, religious and political leaders/analysts, and Ebola-frontline workers), following a semi-structured interview guide. FGDs (n = 10) were conducted with community members. Interviews were recorded with a digital voice recorder and simultaneous note-taking. Participant responses were categorized in terms of their themes and subthemes. Results We identified 3 high-level themes and 15 subthemes (given here in parentheses): (1) inadequate knowledge of the origin or cause of Ebola (belief in a metaphysical origin, insufficient awareness of Ebola transmission via an infected corpse, interpretation of disease as God’s punishment, belief in nosocomial Ebola, poor hygiene, and bathing in the Congo River). Ebola was interpreted as (2) a plot by multinational corporations (fears of genocide, Ebola understood as a biological weapon, concerns over organ trafficking, and Ebola was taken to be the result of business actions). Finally Ebola was rumored to be subject to (3) politicization (political authorities seen as ambivalent, exclusion of some community leaders from response efforts, distrust of political authorities, and distrust in the healthcare system). Conclusions Due to the skepticism against Ebola countermeasures, it is critical to understand widespread beliefs about the disease to implement actions that will be effective, including integrating response with the unmet needs of the population

Sujiaonori-Derived Algal Biomaterials Inhibit Allergic Reaction in Allergen-Sensitized RBL-2H3 Cell Line and Improve Skin Health in Humans

Sujiaonori, a river alga growing in the Kochi prefecture, Japan, contains several bioactive compounds such as sulfated polysaccharides (ulvans), ω-3 fatty acids, and vitamins. Dietary intake of this alga-based supplement has been reported to increase circulatory adiponectin, a salutary hormone that is reported to be associated with healthy longevity and prevents a number of cardiovascular and metabolic disorders. This report highlights the anti-allergic and skin health enhancing effects of Sujiaonori-derived ulvan (Tosalvan) and supplement, respectively. RBL-2H3 cell line was used to investigate the anti-allergic effect of algal SP through the evaluation of β-hexosaminidase activity. Algal sulfated polysaccharides or SP (Tosalvan, Yoshino SP) were extracted from powders of dried alga samples provided by local food manufacturers. Report on the effect of daily dietary intake of Sujiaonori-based supplement on skin health is part of a four-week clinical investigation that, in comparison with a supplement made of 70% corn starch powder and 30% spinach powder mixture (twice 3 g daily), explore the beneficial effects of Sujiaonori algal biomaterial (SBM; 3 g taken twice daily) on cardiovascular, gastrointestinal and skin health in a sample of Japanese women. Transepidermal water loss (TEWL) was the skin health marker used in this study and was measured with the use of a corneometer. Significant reduction of β-hexosaminidase activity was observed in Tosalvan and Yoshino SP-treated cells (vs. control; p &lt; 0.05), whereas dietary intake of SBM markedly reduced TEWL level after four weeks of supplementation, as compared to baseline TEWL (p &lt; 0.001). Additionally, SBM improved TEWL better than the control product (p &lt; 0.001). Findings contained in this report suggest that Sujiaonori-derived Tosalvan and Yoshino SP have anti-allergic potential and that the dietary intake of SBM has a beneficial effect on skin health

Epidemiology of ebolavirus disease (EVD) and occupational EVD in health care workers in Sub-Saharan Africa: Need for strengthened public health preparedness

Ebolavirus disease (EVD) is a severe contagious disease in humans, and health care workers (HCW) are at risk of infection when caring for EVD patients. This paper highlights the epidemiologic profile of EVD and its impact on the health care workforce in Africa. A documentary study was conducted which consisted of a review of available literature regarding the epidemiology of EVD, occupational EVD (OEVD), and work safety issues in Sub-Saharan Africa; the literature findings are enriched by field experiences from the authors. EVD outbreaks have already caused 30,500 cases in humans of whom 12,933 died (as of September 9, 2015), and the number of infected HCW has dramatically increased. All eight HCW infected during the 2014 outbreak in Democratic Republic of the Congo died, whereas during the recent West African EVD epidemic more than 890 HCW were infected, with a case fatality rate of 57%. Occupational exposure to blood and other body fluids due to inadequate use of personal protective equipment and needle stick or sharp injuries are among factors that contribute to the occurrence of OEVD. Prevention of OEVD should be one of the top priorities in EVD outbreak preparedness and management, and research should be conducted to elucidate occupational and other factors that expose HCW to EVD. In addition to regularly training HCW to be adequately prepared to care for patients with EVD, it is critical to strengthen the general health care system and improve occupational safety in medical settings of countries at risk