Radiant heating concept efficient for light-transmitting windows

Single-pane, uncoated windows absorb infrared rays and transmit visible and near-visible wavelengths. Two opposed rod heaters direct infrared rays at the pane, reflectors aid in this heating which prevents condensation. These windows are useful for telescopes and cameras for oceanographic and related studies

Swimming Efficiency of Bacterium Escherichia Coli

We use in vivo measurements of swimming bacteria in an optical trap to determine fundamental properties of bacterial propulsion. In particular, we determine the propulsion matrix, which relates the angular velocity of the flagellum to the torques and forces propelling the bacterium. From the propulsion matrix dynamical properties such as forces, torques, swimming speed and power can be obtained from measurements of the angular velocity of the motor. We find significant heterogeneities among different individuals even though all bacteria started from a single colony. The propulsive efficiency, defined as the ratio of the propulsive power output to the rotary power input provided by the motors, is found to be 0.2%.Comment: 6 page

Contrasting Evidence Within and Between Institutions that Provide Treatment in an Observational Study of Alternate Forms of Anesthesia

In a randomized trial, subjects are assigned to treatment or control by the flip of a fair coin. In many nonrandomized or observational studies, subjects find their way to treatment or control in two steps, either or both of which may lead to biased comparisons. By a vague process, perhaps affected by proximity or sociodemographic issues, subjects find their way to institutions that provide treatment. Once at such an institution, a second process, perhaps thoughtful and deliberate, assigns individuals to treatment or control. In the current article, the institutions are hospitals, and the treatment under study is the use of general anesthesia alone versus some use of regional anesthesia during surgery. For a specific operation, the use of regional anesthesia may be typical in one hospital and atypical in another. A new matched design is proposed for studies of this sort, one that creates two types of nonoverlapping matched pairs. Using a new extension of optimal matching with fine balance, pairs of the first type exactly balance treatment assignment across institutions, so each institution appears in the treated group with the same frequency that it appears in the control group; hence, differences between institutions that affect everyone in the same way cannot bias this comparison. Pairs of the second type compare institutions that assign most subjects to treatment and other institutions that assign most subjects to control, so each institution is represented in the treated group if it typically assigns subjects to treatment or, alternatively, in the control group if it typically assigns subjects to control, and no institution appears in both groups. By and large, in the second type of matched pair, subjects became treated subjects or controls by choosing an institution, not by a thoughtful and deliberate process of selecting subjects for treatment within institutions. The design provides two evidence factors, that is, two tests of the null hypothesis of no treatment effect that are independent when the null hypothesis is true, where each factor is largely unaffected by certain unmeasured biases that could readily invalidate the other factor. The two factors permit separate and combined sensitivity analyses, where the magnitude of bias affecting the two factors may differ. The case of knee surgery in the study of regional versus general anesthesia is considered in detail

A \u3cem\u3eWRKY\u3c/em\u3e Gene from Creosote Bush Encodes an Activator of the Abscisic Acid Signaling Pathway

The creosote bush (Larrea tridentata) is a xerophytic evergreen C3 shrub thriving in vast arid areas of North America. As the first step toward understanding the molecular mechanisms controlling the drought tolerance of this desert plant, we have isolated a dozen genes encoding transcription factors, including LtWRKY21 that encodes a protein of 314 amino acid residues. Transient expression studies with the GFP-LtWRKY21 fusion construct indicate that the LtWRKY21 protein is localized in the nucleus and is able to activate the promoter of an abscisic acid (ABA)-inducible gene, HVA22, in a dosage-dependent manner. The transactivating activity of LtWRKY21 relies on the C-terminal sequence containing the WRKY domain and a N-terminal motif that is essential for the repression activity of some regulators in ethylene signaling. LtWRKY21 interacts synergistically with ABA and transcriptional activators VP1 and ABI5 to control the expression of the HVA22 promoter. Co-expression of VP1, ABI5, and LtWRKY21 leads to a much higher expression of the HVA22 promoter than does the ABA treatment alone. In contrast, the Lt-WRKY21-mediated transactivation is inhibited by two known negative regulators of ABA signaling: 1-butanol, an inhibitor of phospholipase D, and abi1-1, a dominant negative mutant protein phosphatase. Interestingly, abi1-1 does not block the synergistic effect of LtWRKY21, VP1, and ABI5 co-expression, indicating that LtWRKY21, VP1, and ABI5 may form a complex that functions downstream of ABI1 to control ABA-regulated expression of genes

Study of the single body yawed-wing aircraft concept

Areas relating to the development and improvement of the single-fuselage, yawed-wing transonic transport concept were investigated. These included: (1) developing an alternate configuration with a simplified engine installation;(2) determining a structural design speed placard that would allow the engine-airframe match for optimum airplane performance; and (3) conducting an aeroelastic stability and control analysis of the yawed-wing configuration with a flexible wing. A two-engine, single-fuselage, yawed-wing configuration was developed that achieved the Mach 1.2 design mission at 5560 km (3000 nmi) and payload of 18,140 kg (40,000 lb) with a gross weight of 217,700 kg (480,000 lb). This airplane was slightly heavier than the aft-integrated four-engine configuration that had been developed in a previous study. A modified structural design speed placard, which was determined, resulted in a 6% to 8% reduction in the gross weight of the yawed-wing configurations. The dynamic stability characteristics of the single-fuselage yawed-wing configuration were found to be very dependent on the magnitude of the pitch/roll coupling, the static longitudinal stability, and the dihedral effect

Non-gaussianities and the Stimulated creation of quanta in the inflationary universe

Cosmological inflation generates a spectrum of density perturbations that can seed the cosmic structures we observe today. These perturbations are usually computed as the result of the gravitationally-induced spontaneous creation of perturbations from an initial vacuum state. In this paper, we compute the perturbations arising from gravitationally-induced stimulated creation when perturbations are already present in the initial state. The effect of these initial perturbations is not diluted by inflation and survives to its end, and beyond. We consider a generic statistical density operator $\rho$ describing an initial mixed state that includes probabilities for nonzero numbers of scalar perturbations to be present at early times during inflation. We analyze the primordial bispectrum for general configurations of the three different momentum vectors in its arguments. We find that the initial presence of quanta can significantly enhance non-gaussianities in the so-called squeezed limit. Our results show that an observation of non-gaussianities in the squeezed limit can occur for single-field inflation when the state in the very early inflationary universe is not the vacuum, but instead contains early-time perturbations. Valuable information about the initial state can then be obtained from observations of those non-gaussianities.Comment: 25 page

Mesoionic Imines (MIIs): Strong Donors and Versatile Ligands for Transition Metals and Main Group Substrates

We report the synthesis and the reactivity of 1,2,3-triazolin-5-imine type mesoionic imines (MIIs). The MIIs are accessible by a base-mediated cycloaddition between a substituted acetonitrile and an aromatic azide, methylation by established routes and subsequent deprotonation. C=O-stretching frequencies in MII−CO2 and −Rh(CO)2Cl complexes were used to determine the overall donor strength. The MIIs are stronger donors than the N-heterocyclic imines (NHIs). MIIs are excellent ligands for main group elements and transition metals in which they display substituent-induced fluorine-specific interactions and undergo C−H activation. DFT calculations gave insights into the frontier orbitals of the MIIs. The calculations predict a relatively small HOMO–LUMO gap compared to other related ligands. MIIs are potentially able to act as both π-donor and π-acceptor ligands. This report highlights the potential of MIIs to display exciting properties with a huge potential for future development.Fil: Rudolf, Richard. Universitat Stuttgart; AlemaniaFil: Neuman, Nicolás Ignacio. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Santa Fe. Instituto de Desarrollo Tecnológico para la Industria Química. Universidad Nacional del Litoral. Instituto de Desarrollo Tecnológico para la Industria Química; Argentina. Universitat Stuttgart; AlemaniaFil: Walter, Robert R. M.. Universitat Stuttgart; AlemaniaFil: Ringenberg, Mark. R.. Universitat Stuttgart; AlemaniaFil: Sarkar, Biprajit. Universitat Stuttgart; Alemani

Magellan Project: Evolving enhanced operations efficiency to maximize science value

Magellan has been one of NASA's most successful spacecraft, returning more science data than all planetary spacecraft combined. The Magellan Spacecraft Team (SCT) has maximized the science return with innovative operational techniques to overcome anomalies and to perform activities for which the spacecraft was not designed. Commanding the spacecraft was originally time consuming because the standard development process was envisioned as manual tasks. The Program understood that reducing mission operations costs were essential for an extended mission. Management created an environment which encouraged automation of routine tasks, allowing staff reduction while maximizing the science data returned. Data analysis and trending, command preparation, and command reviews are some of the tasks that were automated. The SCT has accommodated personnel reductions by improving operations efficiency while returning the maximum science data possible

Anesthesia Technique, Mortality, and Length of Stay After Hip Fracture Surgery

Importance: More than 300 000 hip fractures occur each year in the United States. Recent practice guidelines have advocated greater use of regional anesthesia for hip fracture surgery. Objective: To test the association of regional (ie, spinal or epidural) anesthesia vs general anesthesia with 30-day mortality and hospital length of stay after hip fracture