13 research outputs found

    Cultural barriers to male partnersā€™ involvement in antenatal care in Limpopo province

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    Background:Ā Participation of male partners in antenatal care (ANC) is a complicated process that involves social and behavioural transformation. It necessitates that males take a more active part in reproductive health. Menā€™s participation in prenatal care has been linked to beneficial health outcomes such as enhanced maternal health outcomes across the world. However, culture has been identified as a barrier to male partnersā€™ participation in prenatal care. Aim:Ā The aim of the study was to explore and describe the cultural barriers to male partner involvement in ANC. Setting:Ā The study focussed on selected clinics and hospitals under Vhembe District, Limpopo province. Methods:Ā Qualitative, exploratory, descriptive, and contextual research design was used in this study. Qualitative data were collected through individual semi-structured interviews and Focus Group Discussions (FGDs). A thematic analysis approach was used to analyse the collected data from semi-structured interviews and FGDs. Results:Ā The findings revealed three themes: cultural beliefs and practices that affect male partnersā€™ involvement in ANC; gender-related barriers that affect male partnersā€™ involvement in ANC; and socioeconomic barriers to male partnersā€™ involvement in ANC. Conclusion:Ā The studyā€™s findings revealed that certain cultural beliefs and practices are a stumbling block to male partnersā€™ involvement in antenatal healthcare. Contribution:Ā Culturally based developed strategy might help in improving the knowledge and practices of male partners in ANC

    Heterologous expression of equine influenza virus major surface glycoproteins and determination of their immunogenicity in animal models

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    Abstract: Equine influenza virus (EIV) is the major cause of respiratory tract infection in horses worldwide. The most effective preventative and control measure against EIV infections is by vaccination. The currently commercialized EIV vaccines are propagated in chicken embryonated eggs. However, vaccine production in this manner has several well-recognised drawbacks (supply of chicken eggs, contamination by egg protein and yield in eggs, cost, disposal of waste, working directly with the highly pathogenic EIV etc.). These bottlenecks necessitate the development of an alternative EIV vaccine production strategy. Like other influenza viruses, EIV comprises of two major surface glycoproteins named hemagglutinin (HA) and neuraminidase (NA). The HA protein is the principal antigen against which neutralizing antibodies are produced, making it an obvious target for vaccine formulation against EIV infections. The NA protein, although lessimportant in contrast to the HA protein, is also used in some instances for vaccine formulation. The addition of the NA protein with the HA component is known to boost antibodyresponse. The aim of this present study was to use recombinant DNA (rDNA) technology for heterologous production of recombinant proteins(HA/NA) to be used in the development of HA, a combination of HA and NA EIV vaccine candidates formulated with and without an adjuvant. The Yarrowia lipolytica yeast system was used in this present study for heterologous expression of HA and NA EIV major surface glycoproteins. This system was chosen for its multifaceted advantages it provides (safe, costeffective, high yield and, scalable). The HA/NA genes were sub-cloned into a yeast expression vector (pKOV410) following their release from a donor vector (pUC57) by restriction enzyme digest. Recombinant pKOV410-HA/NA vectors were subsequently linearized with NotI restriction enzyme to separate the expression cassettes from the DNA moiety to facilitate the transformation of the expression cassettes into the yeast cell genome. The sodium dodecyl sulphatepolyacrylamide gel electrophoresis (SDS-PAGE) was used to determine the expression of the recombinant HA/NA proteins. The produced vaccine candidates were tested for their immunogenicity in clinical studies using guinea pigs as animal models. The vaccine types were able to induce a positive antibodyresponse in the first and second week post-vaccination (PV) but were seronegative following booster dose. Therefore, intensive research is needed towards the improvement of boosting strategies, for example, the alternative route of administration and purification of proteins should be the center of focus in the improvement of a better alternative yeast-based vaccine platform.M.Sc. (Biochemistry

    Qualification problem of intentional infliction of serious bodily injury which, as a result of the negligence of the offender, has been the cause of the death of the victim

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    TiesÄ«bu zinātneTiesÄ«bu zinātneLaw ScienceLaw ScienceAutore izstrādāja maÄ£istra darbu ar nosaukumu ā€žTÄ«Å”a smaga miesas bojājuma nodarÄ«Å”anas, kas vainÄ«gā neuzmanÄ«bas dēļ bija par iemeslu cietuŔā nāvei, kvalifikācijas problēmasā€. Autore darbā pētÄ«s tÄ«Å”a smaga miesas bojājuma nodarÄ«Å”anu, kas vainÄ«gā neuzmanÄ«bas dēļ bijis par iemeslu cietuŔā nāvei, kvalifikācijas problēmas, kā arÄ« analizēs likumdoÅ”anā pastāvoŔās problēmas, kas saistÄ«tas ar noziedzÄ«gu nodarÄ«jumu noŔķirÅ”anu ar citiem pret veselÄ«bu un dzÄ«vÄ«bu vērstiem noziegumiem, tas ir, slepkavÄ«bu bez pastiprinoÅ”iem vai mÄ«kstinoÅ”iem apstākļiem un nonāvÄ“Å”anu aiz neuzmanÄ«bas. Autores izvirzÄ«tais maÄ£istra darba mērÄ·is ā€“ izpētot tÄ«Å”a smaga miesa bojājuma nodarÄ«Å”anas, kas vainÄ«gā neuzmanÄ«bas dēļ bijis par iemeslu cietuŔā nāvei, kvalifikācijas problēmas, konstatēt tiesiskās problēmas un piedāvāt to risinājumus. PētÄ«juma jautājums ā€“ Kāds pamats domāt, ka regulējumā ir kvalifikācijas problēmas saistÄ«bā ar tÄ«Å”a smaga miesas bojājuma nodarÄ«Å”anu, kas vainÄ«gā neuzmanÄ«bas dēļ bijis par iemeslu cietuŔā nāvei, un kādi var bÅ«t risinājumi Å”o noziegumu pareizai kvalifikācijai? PētÄ«juma objekts ir ā€“ tÄ«Å”a smaga miesas bojājuma nodarÄ«Å”anas, kas vainÄ«gā neuzmanÄ«bas dēļ bijis par iemeslu cietuŔā nāvei, ar kvalifikāciju saistÄ«tās tiesiskās attiecÄ«bas. Neskatoties uz ilgu gadu pastāvoÅ”u problēmu, kas saistÄ«ta ar Krimināllikuma 125.panta treŔās daļas pareizu kvalifikāciju un noŔķirÅ”anu no citiem pret veselÄ«bu un dzÄ«vÄ«bu vērstiem noziedzÄ«giem nodarÄ«jumiem, kā arÄ« neskatoties uz vairākkārtÄ«giem tiesu prakses apkopojumiem, kuros konkrēti tika norādÄ«ti kritēriji pēc kuriem jāvadās, noŔķirot minētos noziedzÄ«gus nodarÄ«jumus, joprojām minētās problēmas pastāv. Galvenā problēma ir subjektÄ«vas puses nepietiekama analÄ«zē un nodoma pareiza noteikÅ”ana. MaÄ£istra darbā tika izmantoti gan Latvijas, gan arÄ« ārvalstu autoru darbi tādās jomās kā tiesÄ«bu teorija, krimināltiesÄ«bas, kriminoloÄ£ija. Papildus tika izmantoti juridiskās prakses materiāli, normatÄ«vie akti un interneta resursu publiskotie materiāli. MaÄ£istra darba apjoms 82 lapas. MaÄ£istra darbs sastāv no ievada, četrām nodaļām, nobeigumā izteiktiem secinājumiem un priekÅ”likumiem, kā arÄ« izmantotās literatÅ«ras un avotu saraksta.The author has developed a masterā€™s thesis called ā€œIssues of qualifying murder and commitment of intentional infliction of serious bodily injury which, as a result of the negligence of the offender, has been the cause of the death of the victimā€. The author has examined the issues of qualifying murder and commitment of intentional infliction of serious bodily injury which, as a result of the negligence of the offender, has been the cause of the death of the victim, as well as the existing legislative issues related to separating a criminal offence from other offences against a personā€™s health or life, namely, murder without aggravating or mitigating circumstances and homicide through negligence. The goal of the thesis set by the author is as follows: after having examined the issues of qualifying murder and commitment of intentional infliction of serious bodily injury which, as a result of the negligence of the offender, has been the cause of the death of the victim, to detect legal issues and offer solutions to them. The research question is as follows: What is the ground for the assumption that the issues exist within the legal framework regarding commitment of intentional infliction of serious bodily injury which, as a result of the negligence of the offender, has been the cause of the death of the victim, and what solutions are there to qualify these offences in a proper way? The object of the research is as follows: the legal relations related to the qualification of commitment of intentional infliction of serious bodily injury which, as a result of the negligence of the offender, has been the cause of the death of the victim. Despite the long-existing issues related to proper qualification and separation of Part 3 of Section 125 of the Criminal Law from other criminal offences against a personā€™s health and life, as well as despite numerous collections of case laws that provide criteria to be followed, the issues still exist upon separating the above-mentioned criminal offences. Yet the main issue is an insufficient analysis of the subjective side and the proper determination of the intention. The present thesis has employed different theories by both Latvian and foreign scholars regarding such domains as legal theory, criminal law and criminology. Additionally legal practice materials, regulatory acts and materials available from the internet resources have been examined. The volume of the present paper is 82 pages. It consists of the introduction, four chapters, conclusions and proposals set out in the concluding part, as well as the list of sources used

    Male partnersā€™ views of involvement in maternal healthcare services at Makhado Municipality clinics, Limpopo Province, South Africa

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    Background: Male partners have a strong influence on pregnant partnersā€™ health and their access to care. Their involvement is critical in the delivery and uptake of maternal healthcare services and improving maternal and child health outcomes. Aim: The study sought to determine male partnersā€™ views on their involvement in maternal healthcare services. Setting: The Makhado Municipalityā€™s Kutama, Madombidzha and Vleifontein clinics. Methods: A qualitative study design, which is exploratory, descriptive and contextual in nature, was used. The population comprised 15 men whose partners had been pregnant within the last 2 years. A non-probability, purposive sampling procedure was used. Data were collected via in-depth individual interviews using a voice recorder and an interview schedule guide. Teschā€™s open coding method was used to analyse data. Results: The findings revealed one major theme, namely that maternal health issues are viewed as a womanā€™sdomain; and three sub-themes: culture and participation in childbirth, male partnersā€™ employment status, and male partnersā€™ unwillingness to participate in maternal health issues. Conclusions: The involvement of male partners in maternal healthcare services, and further research in promoting this activity, should be proposed to policymakers. Keywords: Views, partners, involvement, maternal health care services, antenatal care, labour and postnatal care
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