12 research outputs found
ATP-dependent chromatosome remodeling
Chromatin serves to package, protect and organize the complex eukaryotic genomes to assure their stable inheritance over many cell generations. At the same time, chromatin must be dynamic to allow continued use of DNA during a cell's lifetime. One important principle that endows chromatin with flexibility involves ATP-dependent `remodeling' factors, which alter DNA-histone interactions to form, disrupt or move nucleosomes. Remodeling is well documented at the nucleosomal level, but little is known about the action of remodeling factors in a more physiological chromatin environment. Recent findings suggest that some remodeling machines can reorganize even folded chromatin fibers containing the linker histone H1, extending the potential scope of remodeling reactions to the bulk of euchromatin
Broadband multi-wavelength properties of M87 during the 2017 Event Horizon Telescope campaign
In 2017, the Event Horizon Telescope (EHT) Collaboration succeeded in capturing the first direct image of the
center of the M87 galaxy. The asymmetric ring morphology and size are consistent with theoretical expectations
for a weakly accreting supermassive black hole of mass ∼6.5 × 109Me. The EHTC also partnered with several
international facilities in space and on the ground, to arrange an extensive, quasi-simultaneous multi-wavelength
campaign. This Letter presents the results and analysis of this campaign, as well as the multi-wavelength data as a
legacy data repository. We captured M87 in a historically low state, and the core flux dominates over HST-1 at
high energies, making it possible to combine core flux constraints with the more spatially precise very long
baseline interferometry data. We present the most complete simultaneous multi-wavelength spectrum of the active
nucleus to date, and discuss the complexity and caveats of combining data from different spatial scales into one
broadband spectrum. We apply two heuristic, isotropic leptonic single-zone models to provide insight into the
basic source properties, but conclude that a structured jet is necessary to explain M87’s spectrum. We can exclude
that the simultaneous γ-ray emission is produced via inverse Compton emission in the same region producing the
EHT mm-band emission, and further conclude that the γ-rays can only be produced in the inner jets (inward of
HST-1) if there are strongly particle-dominated regions. Direct synchrotron emission from accelerated protons and
secondaries cannot yet be excluded.http://iopscience.iop.org/2041-8205am2022Physic