Five Years Study of Recurrent Febrile Seizure Risk Factors

Background: Nearly one-third of febrile seizure patients suffered recurrent febrile seizures.  Several risk factors contribute to this recurrence, namely young age, family history of febrile seizures, low body temperature and rapid duration of fever before onset of seizures. Recently, the types of seizure and gender have been stated increasing risk of this recurrence. The objectives of this study was to identify the  risk factors of recurrent febrile seizures.Methods: A descriptive study was carried out by retrieving data from inpatient medical records during the period of January 1st, 2009 to December 31st, 2013 at one of the top referral hospitals in West Java, Indonesia.  Variables of this study were the first febrile seizure age, gender, type of febrile seizure, a family history of febrile seizure, a family history of epilepsy, body temperature when febrile seizure occurred and duration of fever before onset of seizure. The collected data were tabulated by frequency and percentage and displayed in tables.Results: Out of 154 patients with febrile seizures 58 suffered recurrent febrile seizures. Forty three percent had a first febrile seizure at the age of under12 months, 72% were male, 46% had fever less than 24 hours before the onset of seizure, 65% had complex febrile seizures, 28% had positive family history of febrile seizures, and 5% had positive family history of epilepsy. Conclusions: The risk factors for recurrent febrile seizures are young age, male, rapid duration of fever before onset of seizure and complex febrile seizure. DOI: 10.15850/amj.v4n2.108

Undernutrition as Risk Factor of Hydrocephalus Prevalence in Children with Tuberculous Meningitis

Background: Hydrocephalus is the most frequent neurological complication in children with tuberculous meningitis. Tuberculosis infection cannot be separated from nutritional status. Children with undernutrition have decreased immunity thus could affect clinical manifestation of tuberculous meningitis. This study was conducted to identify the relationship between undernutrition and the prevalence of hydrocephalus in tuberculous meningitis.Methods: An analytic observational study was carried out to 38 medical records of children with tuberculous meningitis in Dr. Hasan Sadikin General Hospital from 2007 to 2015. Variables that were studied included gender, age, advanced stage of disease, motoric paralysis, history of seizure, nutritional status and hydrocephalus. The collected data were analyzed using Chi-Square test. Results: Out of 21 subjects with undernutrition, 11 subjects were found to have hydrocephalus. The analysis using chi-square was statistically significant (p=0.009). Prevalence ratio=4.45 (CI 95% 1.14−45.43), meaning tuberculous meningitis children with undernutrition were at risk of hydrocephalus 4.45 times greater than children with normal nutritional status.Conclusions: Undernutrition may increase the risk of hydrocephalus in children with tuberculous meningitis. [AMJ.2017;4(1):143–7] DOI: 10.15850/amj.v4n1.103

Knowledge and Attitude on Febrile Seizure among Mothers with Under-Five Children

Background: Febrile seizures frequently occur in children under 5 years old and usually create fear and anxiety among parents. Poor understanding of febrile seizure among parents contributes to mismanagement of seizure. The objective of this study was to identify the knowledge and attitude on febrile seizure among mothers of under five children.Methods: This descriptive community-based survey comprised of 96 mothers with under 5 children who were chosen through randomization. This survey was, conducted in Hegarmanah Village, Jatinangor, West Java, Indonesia in October 2013. Data were collected using a questionnaire and analyzed using frequency analysis.Results: Fifty nine respondents (61%) considered that high fever in their children will result in seizure and 63 mothers (65%) stated that this condition was a life-threatening situation which could lead to brain damage (50%) and paralysis (50%). There were some respondents who would manage seizure by shaking (27%) or holding the child tightly during seizure (22%) and putting spoon into the children mouth (59%). Sixty respondents (62.5%) prevented febrile seizure by giving them coffee.Conclusions: Knowledge and attitude regarding febrile seizure is good, but the knowledge and attitude towards the outcome and what to do during febrile seizures occasion are still poor. [AMJ.2016;3(4):649–54] DOI: 10.15850/amj.v3n4.95

Five Years Study of Recurrent Febrile Seizure Risk Factors

Background: Nearly one-third of febrile seizure patients suffered recurrent febrile seizures.  Several risk factors contribute to this recurrence, namely young age, family history of febrile seizures, low body temperature and rapid duration of fever before onset of seizures. Recently, the types of seizure and gender have been stated increasing risk of this recurrence. The objectives of this study was to identify the  risk factors of recurrent febrile seizures.Methods: A descriptive study was carried out by retrieving data from inpatient medical records during the period of January 1st, 2009 to December 31st, 2013 at one of the top referral hospitals in West Java, Indonesia.  Variables of this study were the first febrile seizure age, gender, type of febrile seizure, a family history of febrile seizure, a family history of epilepsy, body temperature when febrile seizure occurred and duration of fever before onset of seizure. The collected data were tabulated by frequency and percentage and displayed in tables.Results: Out of 154 patients with febrile seizures 58 suffered recurrent febrile seizures. Forty three percent had a first febrile seizure at the age of under12 months, 72% were male, 46% had fever less than 24 hours before the onset of seizure, 65% had complex febrile seizures, 28% had positive family history of febrile seizures, and 5% had positive family history of epilepsy. Conclusions: The risk factors for recurrent febrile seizures are young age, male, rapid duration of fever before onset of seizure and complex febrile seizure. DOI: 10.15850/amj.v4n2.108

Knowledge and Attitude on Febrile Seizure among Mothers with Under-Five Children

Background: Febrile seizures frequently occur in children under 5 years old and usually create fear and anxiety among parents. Poor understanding of febrile seizure among parents contributes to mismanagement of seizure. The objective of this study was to identify the knowledge and attitude on febrile seizure among mothers of under five children.Methods: This descriptive community-based survey comprised of 96 mothers with under 5 children who were chosen through randomization. This survey was, conducted in Hegarmanah Village, Jatinangor, West Java, Indonesia in October 2013. Data were collected using a questionnaire and analyzed using frequency analysis.Results: Fifty nine respondents (61%) considered that high fever in their children will result in seizure and 63 mothers (65%) stated that this condition was a life-threatening situation which could lead to brain damage (50%) and paralysis (50%). There were some respondents who would manage seizure by shaking (27%) or holding the child tightly during seizure (22%) and putting spoon into the children mouth (59%). Sixty respondents (62.5%) prevented febrile seizure by giving them coffee.Conclusions: Knowledge and attitude regarding febrile seizure is good, but the knowledge and attitude towards the outcome and what to do during febrile seizures occasion are still poor. [AMJ.2016;3(4):649–54] DOI: 10.15850/amj.v3n4.95

Association between 25-Hydroxyvitamin D and Mental-Emotional Status in Children during Their First 1000 Days of Life

Vitamin D receptors are widely expressed in brain tissue, including in the limbic system that plays a role in children's mental and emotional development. This study aimed to analyze the relationship between 25-(OH)-D level and children's mental-emotional development during their first 1000 days of life. A cross-sectional study was conducted on children aged ≤2 years old in Waled and Sukabumi regions using secondary data from previous cohort investigations entitled "The Role of Vitamin D in Efforts to Reduce Maternal and Infant mortality". The measurement of 25-(OH)-D concentration and assessment of the mental-emotional development were performed using the Ages and Stages Questionnaires: Social-Emotional (ASQ-SE) questionnaire. Other child and maternal characteristics, and several laboratory results, were also obtained. Statistical analyses were performed using the Spearman rank, Pearson correlation test, and multivariate linear regression analysis. A total of ninety-two children were included, and the median vitamin D level of the population was 20.17 ng/mL (IQR 4.43–49.97). The correlation analysis showed that no significant relationship between children's mental-emotional scores and the parameters tested, including the concentration of 25-(OH)-D (correlation coefficient 0.08; p=0.446). There was no relationship between the vitamin D concentration and mental-emotional development. Based on these results, it is concluded that there is no correlation between 25-(OH)-D concentration and children’s mental-emotional development during the first 1000 days of life. However, further investigations are recommended to eliminate various confounding factors

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