Randomized resonators as uniquely identifiable anti-counterfeiting tags

We discuss how LC circuits with randomized properties can be used as anti-counterfeiting tags. Work in progress is presented. Test circuits made using thin film technology easily achieve 20 to 3 bits of identification capacity. We describe our experimental setup, the radiofrequent response curves, and the stable features that can be extracted from them

A new package for silicon biosensors

A new concept is presented for packaging of silicon biosensor chips in disposable cartridges for medical diagnostic applications. Manufacturing of these devices requires connection and packaging techniques for fluidic, mechanical and electrical functions. The presented packaging concept consists of a Molded Interconnection Device (MID), a mm2-sized silicon biosensor chip, a flexfoil, and a fluidic part. The device shows reliable electrical interconnection between sensor chip and readout electronics. Also the fluidic pathway is proved to be reliable during operation. The packaging concept allows easy further integration of electrical and mechanical functions

A new package for silicon biosensors

A new concept is presented for packaging of silicon biosensor chips in disposable cartridges for medical diagnostic applications. Manufacturing of these devices requires connection and packaging techniques for fluidic, mechanical and electrical functions. The presented packaging concept consists of a Molded Interconnection Device (MID), a mm2-sized silicon biosensor chip, a flexfoil, and a fluidic part. The device shows reliable electrical interconnection between sensor chip and readout electronics. Also the fluidic pathway is proved to be reliable during operation. The packaging concept allows easy further integration of electrical and mechanical functions

Packaging of silicon sensors for microfluidic bio-analytical applications

A new industrial concept is presented for packaging biosensor chips in disposable microfluidic cartridges to enable medical diagnostic applications. The inorganic electronic substrates, such as silicon or glass, are integrated in a polymer package which provides the electrical and fluidic interconnections to the world and provides mechanical strength and protection for out-of-lab use. The demonstrated prototype consists of a molded interconnection device (MID), a silicon-based giant magneto-resistive (GMR) biosensor chip, a flex and a polymer fluidic part with integrated tubing. The various processes are compatible with mass manufacturing and run at a high yield. The devices show a reliable electrical interconnection between the sensor chip and readout electronics during extended wet operation. Sandwich immunoassays were carried out in the cartridges with surface functionalized sensor chips. Biological response curves were determined for different concentrations of parathyroid hormone (PTH) on the packaged biosensor, which demonstrates the functionality and biocompatibility of the devices. The new packaging concept provides a platform for easy further integration of electrical and fluidic functions, as for instance required for integrated molecular diagnostic devices in cost-effective mass manufacturing

Packaging of silicon sensors for microfluidic bio-analytical applications

A new industrial concept is presented for packaging biosensor chips in disposable microfluidic cartridges to enable medical diagnostic applications. The inorganic electronic substrates, such as silicon or glass, are integrated in a polymer package which provides the electrical and fluidic interconnections to the world and provides mechanical strength and protection for out-of-lab use. The demonstrated prototype consists of a molded interconnection device (MID), a silicon-based giant magneto-resistive (GMR) biosensor chip, a flex and a polymer fluidic part with integrated tubing. The various processes are compatible with mass manufacturing and run at a high yield. The devices show a reliable electrical interconnection between the sensor chip and readout electronics during extended wet operation. Sandwich immunoassays were carried out in the cartridges with surface functionalized sensor chips. Biological response curves were determined for different concentrations of parathyroid hormone (PTH) on the packaged biosensor, which demonstrates the functionality and biocompatibility of the devices. The new packaging concept provides a platform for easy further integration of electrical and fluidic functions, as for instance required for integrated molecular diagnostic devices in cost-effective mass manufacturing