Low-power FM transmitter for use in neural recording applications

Journal ArticleWe present a low power FM transmitter for use in neural recording telemetry. The transmitter consists of a low noise biopotential amplifier and a voltage controlled oscillator used to transmit the amplified neural signals at a frequency of 433 MHz. The circuit is powered through a transcutaneous, inductive link. The power consumption of the transmitter is measured to be 465 μW. Using a 1/8-wavelength monopole antenna, a received power level was measured to be -54.5 dBm at a distance of one meter

Highly Sensitive Readout Interface for Real-Time Differential Precision Measurements with Impedance Biosensors

Field deployment is critical to developing numerous sensitive impedance transducers. Precise, cost-effective, and real-time readout units are being sought to interface these sensitive impedance transducers for various clinical or environmental applications. This paper presents a general readout method with a detailed design procedure for interfacing impedance transducers that generate small fractional changes in the impedance characteristics after detection. The emphasis of the design is obtaining a target response resolution considering the accuracy in real-time. An entire readout unit with amplification/filtering and real-time data acquisition and processing using a single microcontroller is proposed. Most important design parameters, such as the signal-to-noise ratio (SNR), common-mode-to-differential conversion, digitization configuration/speed, and the data processing method are discussed here. The studied process can be used as a general guideline to design custom readout units to interface with various developed transducers in the laboratory and verify the performance for field deployment and commercialization. A single frequency readout unit with a target 8-bit resolution to interface differentially placed transducers (e.g., bridge configuration) is designed and implemented. A single MCU is programmed for real-time data acquisition and sine fitting. The 8-bit resolution is achieved even at low SNR levels of roughly 7 dB by setting the component values and fitting algorithm parameters with the given methods

Positionally-independent and extended read range resonant sensors applied to deep soil moisture monitoring

Here we detail an inductively coupled extender (ICE) and resonant (LC) sensor to monitor soil moisture using a portable reader. Significant advances of this ICE-LC design are extending typical LC sensor read range over a meter and reducing positional alignment sensitivity between reader and sensor. An analytical model validates the working principle and feasibility of the ICE-LC system. Prototypes of the ICE-LC sensor were built and optimized in terms of sensitivity and power transfer (single and four turns for ICE top and bottom coils, respectively). Soil moisture tests validated the ICE-LC improvements on minimized positional alignment sensitivity and extended read range, transducing a decrease in resonant frequency with increasing soil moisture. When calibrating with existing wired approaches, the ICE-LC sensor had a reproducible, linear sensor gain of 4.52%moisture content/MHz with an R2 of 0.745 and RMSE of 2.41%. A smaller, planar form factor of the ICE-LC sensor was also tested and exhibited reduced positional alignment sensitivity between reader and sensor at shorter read ranges. This initial study demonstrates the feasibility of the ICE-LC resonant sensor as a cost-effective method to monitor soil moisture content throughout the growing season at many field locations.This is a manuscript of an article published as Chan, Yee Jher, Adam R. Carr, Subhanwit Roy, Caden M. Washburn, Nathan M. Neihart, and Nigel F. Reuel. "Positionally-independent and extended read range resonant sensors applied to deep soil moisture monitoring." Sensors and Actuators A: Physical 333 (2022): 113227. DOI: 10.1016/j.sna.2021.113227. Copyright 2021 Elsevier B.V. Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0). Posted with permission

AC and DC Differential Bridge Structure Suitable for Electrochemical Interfacial Capacitance Biosensing Applications

This paper presents a capacitive differential bridge structure with both AC and DC excitation and balancing capability for low cost electrode-solution interfacial capacitance biosensing applications. The proposed series RC balancing structure offers higher sensitivity, lower susceptibility to common-mode interferences, and drift control. To evaluate the bridge performance in practice, possible effects of initial bridge imbalance due to component mismatches are investigated considering the required resolution of the balancing networks, sensitivity, and linearity. This evaluation is also a guideline to designing the balancing networks, balancing algorithm and the proceeding readout interface circuitry. The proposed series RC bridge structure is implemented along with a custom single frequency real-time amplification/filtering readout board with real-time data acquisition and sine fitting. The main specifications for the implemented structure are 8-bit detection resolution if the total expected fractional capacitance change at the interface is roughly 1%. The characterization and measurement results show the effectiveness of the proposed structure in achieving the design target. The implemented structure successfully achieves distinct detection levels for tiny total capacitance change at the electrode-solution interface, utilizing Microcystin-(Leucine-Arginine) toxin dilutions as a proof of concept

Towards Wireless Characterization of Solvated Ions with Uncoated Resonant Sensors

Uncoated resonant sensors are presented here for wireless monitoring of solvated ions, with progress made toward monitoring nitrates in agricultural runoff. The sensor, an open-circuit Archimedean coil, is wirelessly interrogated by a portable vector network analyzer (VNA) that monitors the scattering parameter response to varying ionic concentrations. The sensor response is defined in terms of the resonant frequency and the peak-to-peak amplitude of the transmission scattering parameter profile (|S21|). Potassium chloride (KCl) solutions with concentrations in the range of 100 nM – 4.58 M were tested on nine resonators having different length and pitch sizes to study the effect of sensor geometry on its response to ion concentration. The resonant sensors demonstrated an ion-specific response, caused by the variations in the relative permittivity of the solution, which was also a function of the resonator geometry. A lumped circuit model, which fit the experimental data well, confirms signal transduction via change in solution permittivity. Also, a ternary ionic mixture (composed of potassium nitrate (KNO3), ammonium nitrate (NH4NO3), and ammonium phosphate (NH4H2PO4)) response surface was constructed by testing 21 mixture variations on three different sensor geometries and the phase and magnitude of scattering parameters were monitored. It was determined that the orthogonal responses presented by resonant sensor arrays can be used for quantifying levels of target ions in ternary mixtures. Applications of these arrays include measuring the concentration of key ions in bioreactors, human sweat, and agricultural waters. Preliminary results are shown for calibration standards and real waterway samples in Iowa, USA.</p