Decays of bottom mesons emitting tensor meson in final state using ISGW II model

In this paper, we investigate phenomenologically two-body weak decays of the bottom mesons emitting pseudoscalar/vector meson and a tensor meson. Form factors are obtained using the improved ISGW II model. Consequently, branching ratios for the CKM-favored and CKM-suppressed decays are calculated.Comment: 32 pages, to be published in Phys. Rev.

Can oral iron tablets be replaced by the intravenous iron sucrose in antenatal period? A new thought.

Background: Anaemia is the commonest medical disorder that contributes significantly to maternal morbidity and mortality, preterm delivery, intrauterine growth restriction. Pregnant women are particularly vulnerable to anaemia because they have dual iron requirements both for their growth and growth of foetus. A high proportion of women in both industrialized and developing countries become anaemic during pregnancy. Intravenous iron therapy is safe convenient and effective than oral iron therapy in prevention of iron deficiency anaemia when compliance is the problem. The aim of this study is to compare the efficacy, safety and acceptability of intravenous iron Vs oral iron in prevention of iron deficiency anaemia during pregnancy. The objective of the present research was to study the efficacy, safety and acceptability of oral iron (ferrous fumarate) versus intravenous iron (iron sucrose) for the prevention of iron deficiency anaemia during pregnancy.Methods: It was a prospective comparative case control study without blinding including 400 registered antenatal women in SKNMC and GH, Narhe, Pune. Results were based on collection and analysis of data from samples within study population.Results: There was no significant difference in mean haemoglobin rise between oral group and IV group but there is significant difference between mean ferritin levels between oral group and IV group. In IV group ferritin levels at 36 weeks were almost 1.8 times more than oral group. Acceptability and convenience of IV iron was significantly more than oral iron.Conclusions: Intravenous iron therapy in the form of three divided doses, one in each trimester can be safely used in the antenatal woman as an alternative to prophylactic iron tablets for prevention of iron deficiency anaemia especially in women who are non-compliant or does not tolerate oral iron tablets

A study of vaginal misoprostol tablet versus intra cervical dinoprostone gel for the induction of labour

Background: This was a comparative study conducted to compare the effectiveness of 25 microgram of intravaginal misoprostol with intracervical dinoprostone gel in terms of efficacy of drug, feto-maternal outcome, side effects and complications of drugs.Methods: 400 nulliparas at term, admitted for induction of labor were included in this study. They were randomly selected to receive either intravaginal misoprostol or intracervical dinoprostone gel. Group A (200 women) recieved tablet misoprostol 25 micrograms vaginally 4 hrly to a maximum of 3 doses and Group B (200 women) received dinoprostone gel 0.5mg intracervically 6 hrly to a maximum of 3 doses. Comparison was done in terms of Induction to delivery interval, need for augmentation, LSCS and instrumentation rate, need for NICU admissions and cost effectiveness.Results: The mean induction to delivery interval was less in the misoprostol group than dinoprostone group (12.5 hrs vs. 20 hrs). 78% patients delivered in the first 24 hrs in misoprostol group compared to 52 % patients in dinoprostone group. Group A had a higher success rate (81% vs.76%) and also required less augmentation of labor ( 30% vs. 60%) compared to group B. Need for LSCS was also lower in misoprostol group (11% vs. 16%). Need for instrumentation and incidence of NICU admission was similar in both groups. Misoprostol was more cost effective compared to dinoprostone.Conclusions: The misoprostol group had a shorter induction to delivery interval, more number of deliveries in the first 24 hrs of induction and a reduced need of augmentation of labor with oxytocin. There was no significant difference in the rate of caesarean section, hyper-stimulation syndrome, neonatal and maternal morbidity between the two groups. Thus, misoprosol appears to be safer, cheaper and more efficacious alternative for induction of labor especially for non-fetal indications as compared to dinoprostone gel

Post-operative wound infiltration with dexmedetomidine and magnesium sulphate as adjuvant to levobupivacaine for lumbar laminectomy: a prospective, double blinded, randomized controlled study

Background: Wound infiltration with local anaesthetic is safe and effective technique for providing postoperative analgesia following lumbar laminectomy. The objective of this study was to compare the efficacy of local wound infiltration on postoperative analgesia with levobupivacaine, levobupivacaine plus magnesium sulphate and levobupivacaine plus dexmedetomidine in patient undergoing lumbar laminectomy.Methods: Ninety adult patients were randomly allocated into three groups. After the completion of lumbar laminectomy, the drug was locally infiltrated into the paravertebral muscles on either side. Group L received 10 ml of 0.5% levobupivacaine plus 10 ml normal saline, group LM received 10 ml of 0.5% levobupivacaine plus 500 mg magnesium sulphate (1 ml) plus 9 ml normal saline, group LD received 10 ml of 0.5% levobupivacaine plus 50 µg dexmedetomidine (0.5 ml) plus 9.5 ml normal saline. Postoperative visual analogue scale (VAS) pain score at 0, 1, 2, 4, 6, 8, 12 and 24 hours, time to first rescue analgesic drug and its total dose, quality of recovery score (QoR) and side effects were noted.Results: Postoperative VAS was significantly higher in group L as compared to group LM and LD (p<0.05). The time to first rescue analgesic drug was significantly longer in group LD (11.07±7.20 hr) than group LM (6.20±2.64 hr) and group L (3.93±2.70 hr) (p<0.001). The QoR score was significantly better in group LD as compared to group LM and L postoperatively (<0.01).Conclusions: Addition of magnesium sulphate or dexmedetomidine to levobupivacaine for local wound infiltration demonstrated enhanced postoperative analgesia.