5 research outputs found
Do I need a screening of somatic pathology dentist at a polyclinic reception
According to the testimony of many authors over a number of systemic diseases is accompanied by changes in the state organs and tissues of the mouth. To assess the possibility of clinical and laboratory screening of the most significant systemic diseases - hypertension, diabetes mellitus and chronic pyelonephritis, has been developed screening model that allows for the identification dentally significant somatic pathology or detect signs of physical illness such persons without additional research methods.ΠΠ»Ρ ΡΠΎΠ³ΠΎ, ΡΡΠΎΠ±Ρ ΠΎΡΠ΅Π½ΠΈΡΡ Π²ΠΎΠ·ΠΌΠΎΠΆΠ½ΠΎΡΡΡ ΠΊΠ»ΠΈΠ½ΠΈΠΊΠΎ-Π»Π°Π±ΠΎΡΠ°ΡΠΎΡΠ½ΠΎΠ³ΠΎ ΡΠΊΡΠΈΠ½ΠΈΠ½Π³Π° Π½Π°ΠΈΠ±ΠΎΠ»Π΅Π΅ Π·Π½Π°ΡΠΈΠΌΡΡ
ΡΠΎΠΌΠ°ΡΠΈΡΠ΅ΡΠΊΠΈΡ
Π·Π°Π±ΠΎΠ»Π΅Π²Π°Π½ΠΈΠΉ - Π³ΠΈΠΏΠ΅ΡΡΠΎΠ½ΠΈΡΠ΅ΡΠΊΠΎΠΉ Π±ΠΎΠ»Π΅Π·Π½ΠΈ (ΠΠ), ΡΠ°Ρ
Π°ΡΠ½ΠΎΠ³ΠΎ Π΄ΠΈΠ°Π±Π΅ΡΠ° (Π‘Π) ΠΈ Ρ
ΡΠΎΠ½ΠΈΡΠ΅ΡΠΊΠΎΠ³ΠΎ ΠΏΠΈΠ΅Π»ΠΎΠ½Π΅ΡΡΠΈΡΠ° (Π₯Π), Π±ΡΠ»Π° ΡΠ°Π·ΡΠ°Π±ΠΎΡΠ°Π½Π° ΡΠΊΡΠΈΠ½ΠΈΠ½Π³ΠΎΠ²Π°Ρ ΠΌΠΎΠ΄Π΅Π»Ρ, ΠΏΠΎΠ·Π²ΠΎΠ»ΡΡΡΠ°Ρ Π²ΡΡΠ²Π»ΡΡΡ ΡΡΠΎΠΌΠ°ΡΠΎΠ»ΠΎΠ³ΠΈΡΠ΅ΡΠΊΠΈ Π·Π½Π°ΡΠΈΠΌΡΡ ΡΠΎΠΌΠ°ΡΠΈΡΠ΅ΡΠΊΡΡ ΠΏΠ°ΡΠΎΠ»ΠΎΠ³ΠΈΡ ΠΈΠ»ΠΈ ΠΎΠΏΡΠ΅Π΄Π΅Π»ΡΡΡ ΠΏΡΠΈΠ·Π½Π°ΠΊΠΈ ΡΠΎΠΌΠ°ΡΠΈΡΠ΅ΡΠΊΠΎΠΉ ΠΏΠ°ΡΠΎΠ»ΠΎΠ³ΠΈΠΈ Ρ ΡΠ°ΠΊΠΈΡ
Π»ΠΈΡ Π±Π΅Π· ΠΏΡΠΈΠ²Π»Π΅ΡΠ΅Π½ΠΈΡ Π΄ΠΎΠΏΠΎΠ»Π½ΠΈΡΠ΅Π»ΡΠ½ΡΡ
ΠΌΠ΅ΡΠΎΠ΄ΠΎΠ² ΠΈΡΡΠ»Π΅Π΄ΠΎΠ²Π°Π½ΠΈΡ
Predictive value of risk factors for periodontitis and assessment criteria of the flow of inflammation in periodontitis on the basis of molecular genetic tests
The article analyzes the predictive value of risk factors for periodontitis, the data obtained from a prospective observation of 150 patients. Evaluation of the flow of the process of inflammation was carried out according to morphological study. Saving inflammatory infiltrate in the background of the anti-microbial treatment stage, accompanied by marked clinical effect was regarded as 'poor' outcome of therapy. Discriminant analysis of anamnestic, clinical, morphological and molecular genetic characteristics of patients allowed to calculate graduation factors predicting. The greatest predictive value is a predictor of 'carrier 2R allele of the gene IL-1 RN, IL-1 family1. Following graduation in molecular genetics predictor is β3R allele of the gene IL-4 and the last one -'allele-308A' gene TNFΞ±Β». Of the predictors of having a digital expression, the greatest predictive value are: the 'age' and 'Limitation of the diseaseβ. This combination of predictors can provide the level of correct prediction in 79.8%.Π ΡΡΠ°ΡΡΠ΅ ΠΏΡΠΎΠ²Π΅Π΄Π΅Π½ Π°Π½Π°Π»ΠΈΠ· ΠΏΡΠΎΠ³Π½ΠΎΠ·Π½ΠΎΠΉ ΡΠ΅Π½Π½ΠΎΡΡΠΈ ΡΠ°ΠΊΡΠΎΡΠΎΠ² ΡΠΈΡΠΊΠ° ΠΏΠ°ΡΠΎΠ΄ΠΎΠ½ΡΠΈΡΠ°, Π΄Π°Π½Π½ΡΠ΅ ΠΏΠΎΠ»ΡΡΠ΅Π½Ρ Π² ΡΠ΅Π·ΡΠ»ΡΡΠ°ΡΠ΅ ΠΏΡΠΎΡΠΏΠ΅ΠΊΡΠΈΠ²Π½ΠΎΠ³ΠΎ Π½Π°Π±Π»ΡΠ΄Π΅Π½ΠΈΡ 150 Π±ΠΎΠ»ΡΠ½ΡΡ
. ΠΡΠ΅Π½ΠΊΠ° Ρ
Π°ΡΠ°ΠΊΡΠ΅ΡΠ° ΡΠ΅ΡΠ΅Π½ΠΈΡ ΠΏΡΠΎΡΠ΅ΡΡΠ° Π²ΠΎΡΠΏΠ°Π»Π΅Π½ΠΈΡ ΠΏΡΠΎΠ²ΠΎΠ΄ΠΈΠ»Π°ΡΡ ΠΏΠΎ Π΄Π°Π½Π½ΡΠΌ ΠΌΠΎΡΡΠΎΠ»ΠΎΠ³ΠΈΡΠ΅ΡΠΊΠΎΠ³ΠΎ ΠΈΡΡΠ»Π΅Π΄ΠΎΠ²Π°Π½ΠΈΡ. Π‘ΠΎΡ
ΡΠ°Π½Π΅Π½ΠΈΠ΅ Π²ΠΎΡΠΏΠ°Π»ΠΈΡΠ΅Π»ΡΠ½ΠΎΠ³ΠΎ ΠΈΠ½ΡΠΈΠ»ΡΡΡΠ°ΡΠ° Π½Π° ΡΠΎΠ½Π΅ ΠΏΡΠΎΠ²Π΅Π΄Π΅Π½Π½ΠΎΠ³ΠΎ ΠΏΡΠΎΡΠΈΠ²ΠΎΠΌΠΈΠΊΡΠΎΠ±Π½ΠΎΠ³ΠΎ ΡΡΠ°ΠΏΠ° Π»Π΅ΡΠ΅Π½ΠΈΡ, ΡΠΎΠΏΡΠΎΠ²ΠΎΠΆΠ΄Π°Π²ΡΠ΅Π³ΠΎΡΡ Π²ΡΡΠ°ΠΆΠ΅Π½Π½ΡΠΌ ΠΊΠ»ΠΈΠ½ΠΈΡΠ΅ΡΠΊΠΈΠΌ ΡΡΡΠ΅ΠΊΡΠΎΠΌ, ΡΠ°ΡΡΠ΅Π½ΠΈΠ²Π°Π»ΠΈ ΠΊΠ°ΠΊ Β«Π½Π΅Π±Π»Π°Π³ΠΎΠΏΡΠΈΡΡΠ½ΡΠΉΒ» ΠΈΡΡ
ΠΎΠ΄ ΡΠ΅ΡΠ°ΠΏΠΈΠΈ. ΠΠΈΡΠΊΡΠΈΠΌΠΈΠ½Π°Π½ΡΠ½ΡΠΉ Π°Π½Π°Π»ΠΈΠ· Π°Π½Π°ΠΌΠ½Π΅ΡΡΠΈΡΠ΅ΡΠΊΠΈΡ
, ΠΊΠ»ΠΈΠ½ΠΈΡΠ΅ΡΠΊΠΈΡ
, ΠΌΠΎΡΡΠΎΠ»ΠΎΠ³ΠΈΡΠ΅ΡΠΊΠΈΡ
ΠΈ ΠΌΠΎΠ»Π΅ΠΊΡΠ»ΡΡΠ½ΠΎ-Π³Π΅Π½Π΅ΡΠΈΡΠ΅ΡΠΊΠΈΡ
Ρ
Π°ΡΠ°ΠΊΡΠ΅ΡΠΈΡΡΠΈΠΊ ΠΏΠ°ΡΠΈΠ΅Π½ΡΠΎΠ² ΠΏΠΎΠ·Π²ΠΎΠ»ΠΈΠ» ΡΠ°ΡΡΡΠΈΡΠ°ΡΡ Π³ΡΠ°Π΄Π°ΡΠΈΡ ΡΠ°ΠΊΡΠΎΡΠΎΠ² ΠΏΡΠΎΠ³Π½ΠΎΠ·ΠΈΡΠΎΠ²Π°Π½ΠΈΡ. ΠΠ°ΠΈΠ±ΠΎΠ»ΡΡΡΡ ΠΏΡΠΎΠ³Π½ΠΎΠ·Π½ΡΡ ΡΠ΅Π½Π½ΠΎΡΡΡ ΠΈΠΌΠ΅Π΅Ρ ΠΏΡΠ΅Π΄ΠΈΠΊΡΠΎΡ Β«Π½ΠΎΡΠΈΡΠ΅Π»ΡΡΡΠ²ΠΎ Π°Π»Π»Π΅Π»Ρ 2R Π³Π΅Π½Π° IL-1RN, ΡΠ΅ΠΌΠ΅ΠΉΡΡΠ²Π° IL-1Β». Π‘Π»Π΅Π΄ΡΡΡΠΈΠΌΠΈ ΠΏΠΎ Π³ΡΠ°Π΄Π°ΡΠΈΠΈ ΠΌΠΎΠ»Π΅ΠΊΡΠ»ΡΡΠ½ΠΎ-Π³Π΅Π½Π΅ΡΠΈΡΠ΅ΡΠΊΠΈΠΌ ΠΏΡΠ΅Π΄ΠΈΠΊΡΠΎΡΠΎΠΌ ΡΠ²Π»ΡΠ΅ΡΡΡ Β«Π°Π»Π»Π΅Π»Ρ 3R Π³Π΅Π½Π° IL-4Β» ΠΈ ΠΏΠΎΡΠ»Π΅Π΄Π½ΠΈΠΌ - Β«Π°Π»Π»Π΅Π»Ρ -308Π* Π³Π΅Π½Π° TNFΞ±Β». ΠΠ· ΠΏΡΠ΅Π΄ΠΈΠΊΡΠΎΡΠΎΠ², ΠΈΠΌΠ΅ΡΡΠΈΡ
ΡΠΈΡΡΠΎΠ²ΠΎΠ΅ Π²ΡΡΠ°ΠΆΠ΅Π½ΠΈΠ΅, Π½Π°ΠΈΠ±ΠΎΠ»ΡΡΡΡ ΠΏΡΠΎΠ³Π½ΠΎΠ·Π½ΡΡ ΡΠ΅Π½Π½ΠΎΡΡΡ ΠΈΠΌΠ΅ΡΡ: Β«Π²ΠΎΠ·ΡΠ°ΡΡΒ» ΠΈ Β«Π΄Π°Π²Π½ΠΎΡΡΡ Π±ΠΎΠ»Π΅Π·Π½ΠΈΒ». ΠΠ°Π½Π½ΠΎΠ΅ ΡΠΎΡΠ΅ΡΠ°Π½ΠΈΠ΅ ΠΏΡΠ΅Π΄ΠΈΠΊΡΠΎΡΠΎΠ² ΠΏΠΎΠ·Π²ΠΎΠ»ΡΠ΅Ρ ΠΎΠ±Π΅ΡΠΏΠ΅ΡΠΈΡΡ ΡΡΠΎΠ²Π΅Π½Ρ ΠΊΠΎΡΡΠ΅ΠΊΡΠ½ΠΎΠ³ΠΎ ΠΏΡΠΎΠ³Π½ΠΎΠ·Π° Π² 79,8%
Thermal effects of carbonated hydroxyapatite modified by glycine and albumin
In this work calcium phosphate powders were obtained by precipitation method from simulated solutions of synovial fluid containing glycine and albumin. X-ray diffraction and IR spectroscopy determined that all samples are single-phase and are presented by carbonate containing hydroxyapatite (CHA). The thermograms of solid phases of CHA were obtained and analyzed; five stages of transformation in the temperature range of 25-1000Β°C were marked. It is shown that in this temperature range dehydration, decarboxylation and thermal degradation of amino acid and protein connected to the surface of solid phase occur. The tendency of temperature lowering of the decomposition of powders synthesized from a medium containing organic substances was determined. Results demonstrate a direct dependence between the concentration of the amino acid in a model solution and its content in the solid phase
Elemental composition of solid dental deposits in patients with somatic pathology
For a number of systemic diseases accompanied by changes in the state of organs and tissues of the oral cavity, manifested more active over carious diseases, lesions of the oral mucosa and periodontal, dental plaque formation. Correlation analysis carried out in the ratio of chemical elements in dental plaque in patients with essential hypertension (EH), diabetes mellitus (DM) and chronic pyelonephritis (KP). In individuals with different somatic diseases established differences in the ratio of chemical elements in the dental plaque. It proved that for hypertensive patients characterized by an increased content of cadmium, vanadium, selenium, and molybdenum, with reduced content of rubidium, silver, barium and chromium, diabetics have a higher content of copper and cadmium, and patients with chronic pyelonephritis distinguishes high content of cesium, indium, vanadium and arsenic under reduced content of silver, titanium, chromium, manganese and bromine. Solid dental deposits are irritating to the gum, the retention points are for the accumulation of dental plaque, disrupt the process of self-purification of the periodontal pocket. The elemental composition of dental plaque was studied on the equipment, the accredited Academy of Sciences to carry out research of the biological profile