702 research outputs found
The growing (good) bubbles: insights into US consumers of sparkling wine
Purpose The purpose of this paper is to investigate sparkling wine consumption behavior and preferences of a large sample of US consumers (n=1,096) exploring the differences among genders and generational cohorts. Design/methodology/approach The sample has been drawn from Wine opinions, a specialized market research company with a large online panel of US wine consumers. Data were collected through a survey mailing model, administering a structured questionnaire. Findings Findings reveal that consumption frequency between genders is not statistically different and women generally prefer sparkling wines priced below 15\u201310\u2013$14.99 one. Originality/value The study sheds light on the changing consumer attitudes to create competitive advantages for wineries. Specifically, it provides valuable marketing insights into the peculiarities of sparkling wine consumption for each generation (e.g. price-point preferences and type of wine)
Fructose removal from the diet reverses inflammation, mitochondrial dysfunction, and oxidative stress in hippocampus
Young age is often characterized by high consumption of processed foods and fruit juices rich in fructose, which, besides inducing a tendency to become overweight, can promote alterations in brain function. The aim of this study was therefore to (a) clarify brain effects resulting from fructose consumption in juvenile age, a critical phase for brain development, and (b) verify whether these alterations can be rescued after removing fructose from the diet. Young rats were fed a fructose-rich or control diet for 3 weeks. Fructose-fed rats were then fed a control diet for a further 3 weeks. We evaluated mitochondrial bioenergetics by high-resolution respirometry in the hippocampus, a brain area that is critically involved in learning and memory. Glucose transporter-5, fructose and uric acid levels, oxidative status, and inflammatory and synaptic markers were investigated by Western blotting and spectrophotometric or enzyme-linked immunosorbent assays. A short-term fructose-rich diet induced mitochondrial dysfunction and oxidative stress, associated with an increased concentration of inflammatory markers and decreased Neurofilament-M and post-synaptic density protein 95. These alterations, except for increases in haptoglobin and nitrotyrosine, were recovered by returning to a control diet. Overall, our results point to the dangerous effects of excessive consumption of fructose in young age but also highlight the effect of partial recovery by switching back to a control diet
49° Festival dei Popoli
Il Festival dei Popoli è la più antica e prestigiosa manfestazione intranazionale di documentaristica sociale ed antropologica in Italia. Al suo interno sono previste proiezioni; seminari; convegni; laboratori: ecc
Respiratory muscle deoxygenation during exercise in patients with heart failure demonstrated with near-infrared spectroscopy
AbstractExertional dyspnea in patients with heart failure may be due, in part, to respiratory muscle underperfusion. Near-infrared spectroscopy is a new technique that permits noninvasive assessment of skeletal muscle oxygenation by monitoring changes in nearinfrared light absorption. With use of near-infrared spectroscopy, serratus anterior muscle oxygenation during maximal bicycle exercise was compared in 10 patients with heart failure (ejection fraction 16 ± 5%) and 7 age-matched normal subjects. Oxygen consumption (VO2), minute ventilation (VE) and arterial saturation were also measured. Changes in difference in absorption between 760 and 800 nm, expressed in arbitrary units, were used to detect muscle deoxygenation.Minimal change in this difference in absorption occurred in normal subjects during exercise, whereas patients with heart failure exhibited progressive changes throughout exercise consistent with respiratory muscle deoxygenation (peak exercise: normal 3 ± 6, heart failure 12 ± 4 near-infrared arbitrary units, p < 0.001). At comparable work loads patiente with heart failure had significantly greater minute ventilation and respiratory rate but similar tidal volume when contrasted with normal subjects. However, at peak exercise normal subjects achieved significantly greater minute ventilation and tidal volume with a comparable respiratory rate. No significant arterial desaturation occurred during exercise in either group.These findings indicate that respiratory muscle deoxygenation occurs in patients with heart failure during exercise. This deoxygenation may contribute to the exertional dyspnea experienced by such patients
BoolSurf: Boolean Operations on Surfaces
We port Boolean set operations between 2D shapes to surfaces of any genus, with any number of open boundaries. We combine shapes bounded by sets of freely intersecting loops, consisting of geodesic lines and cubic Bézier splines lying on a surface. We compute the arrangement of shapes directly on the surface and assign integer labels to the cells of such arrangement. Differently from the Euclidean case, some arrangements on a manifold may be inconsistent. We detect inconsistent arrangements and help the user to resolve them. Also, we extend to the manifold setting recent work on Boundary-Sampled Halfspaces, thus supporting operations more general than standard Booleans, which are well defined on inconsistent arrangements, too. Our implementation discretizes the input shapes into polylines at an arbitrary resolution, independent of the level of resolution of the underlying mesh. We resolve the arrangement inside each triangle of the mesh independently and combine the results to reconstruct both the boundaries and the interior of each cell in the arrangement. We reconstruct the control points of curves bounding cells, in order to free the result from discretization and provide an output in vector format. We support interactive usage, editing shapes consisting up to 100k line segments on meshes of up to 1M triangles
Tenascin Expression in Human Placentas during FGR Affected Pregnancies and Umbilical Doppler Velocimetry Correlation
Objective: The aim of this study was to evaluate the expression of some non collagenous extracellular matrix proteins, in particular tenascin, in human placentas of intrauterine growth restricted fetuses with abnormal umbilical Doppler velocimetry. Study Design: Study group (group A) consisted of 23 pregnant women with intrauterine growth restricted fetuses, with or without preeclampsia. Control group (group B) consisted of 10 pregnant women with appropriate fetal weight for gestational age. Placental specimens were collected from biopsies obtained after cesarean delivery. Umbilical artery Doppler velocimetry was performed within four hours from delivery in all patients. Tenascin expression was studied by immunohistochemistry and western blot techniques. Results: A difference in birth weight and placental weight was found in the two groups, being lower in the study group. Umbilical artery Doppler velocimetry showed abnormal patterns in the study group and normal findings in the control one. Tenascin was strongly expressed in placentas from growth restricted fetuses, as shown by immunohistochemistry and by RT-PCR, while it was almost absent in placentas from group B.
Conclusion: A relationship between abnormal Doppler patterns and tenascin distribution in growth restricted fetuses has been observed. The presence of tenascin might be considered as a placental compensatory mechanism in FGR fetuses with abnormal umbilical artery Doppler velocimetry
Effects of conventional and organic feed on the mineral composition of cultured European sea bass (Dicentrarchus labrax)
European sea bass (Dicentrarchus labrax) is a widely consumed marine fish in Mediterranean areas, and different farming techniques are applied for fish culturing to satisfy the growing demand for seafood. The aim of this study was to investigate the effects of conventional and organic feed on the quality of cultured European sea bass (Dicentrarchus labrax) collected during the growth period. The concentrations of ash, moisture, essential macro-elements (Ca, K, Mg, Na and P), micro-elements (Co, Cr, Cu, Fe, Mn, Ni and Zn) and toxic elements (As, Cd, and Pb) were determined in feeds and in fillets of cultured fish. The results were compared to those obtained from wild sea bass. Results showed that the differences between organic diet-fed and conventional diet-fed sea basses varied in relation to the specific element measured and the growth period. The former showed higher concentration of Fe, Mg and Cr, and lower Na content. The amount of P, Na, Fe, Cu and Cr in wild sea bass was significantly (P ≤ 0.05) higher than that found in farmed fish. The levels of toxic elements in cultured sea bass were always within the allowed limit for fishery products. Wild samples had significantly (P ≤ 0.05) higher content of arsenic and lead than farmed sea bass. Cultured fish represent a valuable dietary source of essential macro- and micro-elements. Controlled rearing systems and feedings were related to a decrease in the presence of some toxic metals in cultured fish compared with wild fish
50° Festival dei Popoli
Il Festival dei Popoli è la più antica e prestigiosa manfestazione intranazionale di documentaristica sociale ed antropologica in Italia. Al suo interno sono previste proiezioni; seminari; convegni; laboratori: ecc
Biochemical, antioxidant properties and antimicrobial activity of different onion varieties in the Mediterranean area
Onion (Allium cepa L.) is a very important vegetable crop cultivated worldwide. The bulb is a major source of phytochemicals
useful for human health and rich in sulphur compounds responsible for their typical odour and flavour. In this study, we
investigated the volatile compounds and biochemical properties besides the antimicrobial activity of onion Montoro and Alife
varieties, and of two ecotypes of Vatolla variety (spinning top and tapered shape), cropped in the southern Mediterranean
area (Italy). For all investigated onions, the organosulphur compounds, mainly di- and trisulfides, are the most abundant
compounds. Alife variety showed higher polyphenols amount (8.2 GAE mg/g dw) with respect to the lowest one (3.9 GAE
mg/dw g) in spinning top Vatolla, as well as an higher antioxidant activity (42.37 μmol TE/g dw) about two-fold higher than
those detected in the other varieties. All the onions showed low pungency level, confirming their popular classification as
a sweet onion. The total content of soluble sugars ranged from 461 to 624 mg/g dw; malic acid was the major organic acid
in Alife and Montoro varieties instead for both Vatolla ecotypes citric acid was the most abundant ones. The biochemical
characterization highlighted the three onion varieties as a good source of bioactive compounds. The antimicrobial activity
of the onion extracts pointed out an effective action against three Gram-positive species (B. cereus, L. innocua, S. aureus)
and P. aeruginosa; consequently, they could represent a new source of natural antimicrobial agents
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