Relationship of sperm morphology assessed by strict criteria and outcome of artificial [intrauterine] insemination

Background: The aim of the study was to investigate the relationship between sperm morphology assessed by strict criteria and the outcome of artificial insemination.Methods: 495 consecutive intrauterine insemination (IUI) cycles done for 417 couples in a 1-year period in Gunasheela IVF Center were studied. In all cases controlled ovarian stimulation and hCG timed IUI were performed. In all cases the inseminating motile sperm count after sperm preparation (at least one sample) was 20 million/ml and motility was 90% Grade A. Sperm morphology was assessed by strict criteria.Results: Overall the pregnancy rates were significantly higher in cases with ≥14% normal morphology (23%) and in cases with 10-13% normal morphology (14%). This was in contrast to the pregnancy rates in cases with <10% normal morphology group (8%). Further follow up of the outcome of pregnancies between the ≥10% normal morphology and <10% normal morphology groups did not show any increased loss of pregnancies/anomalies in the <10% normal morphology group but this was not statistically significant as the number of pregnancies in the <10% normal morphology group was very less (8 out of 87).Conclusions: These results emphasize the significance of sperm morphology as a predictor of pregnancy outcome (esp. pregnancy rates) in the IUI outcome

Multiple sclerosis in pregnancy- a case report

Multiple sclerosis is primarily a disease of women in their reproductive years. Relapse rate decreases during pregnancy and rises after delivery. Pregnancy and puerperium have opposite effects on the course of the disease. The case presented is that of a second gravida who was a known case of multiple sclerosis. She was managed conservatively during pregnancy and puerperium

Pregnancy outcome in working women with work place stress

Background: The employment rate of mothers has increased worldwide in recent years. So, there is concern about possible effects of work related risk factors and pregnancy outcome in working women. As a growing percentage of women work outside home before, during, and after pregnancy in most countries and its related occupational factors deserve to be studied in relation to pregnancy outcomes. To identify the effect of work place stress, on pregnancy and perinatal outcome.Methods: 100 pregnant working women, who were visiting the antenatal care unit and labour room taken into study. They were interviewed using predesigned questionnaire, Physical activity questionnaire, Workplace Stress Survey. Statistical analysis performed using SPSS version 21.Results: Mean age was 27yrs, with hrs of working/wk of 47hrs, 41 women studied were working in garment factories,46% of them had complications during their antenatal period, 56% of them were primigravidas.  Among studied working conditions, working more than 40 hours/ week was significantly associated with high rates of preterm delivery (12%) and Small for gestational age (SGA) (22%) was significantly increased with high work stress.Conclusions: Among the studied, work conditions for working women working more than 40 hours/week, social stress index were found to be a significant risk factor for adverse pregnancy outcomes. General practice physical activity (GPPA) 80% of both active and moderately active women had some problems. In work place stress survey (WSS), 100% of women encountering problems at work place had problems during their pregnancy, 72% of women who handled stress moderately had problems. Therefore, as long as the health of the pregnant woman permits her to continue work during pregnancy that is not stressful or overloading for her, no adverse effect on pregnancy outcomes is expected

A rare case of primary parasitic leiomyoma

We report a rare case of a parasitic fibroid in a 42 year old woman who presented with mass per abdomen and backache. Ultrasound showed a mass suggestive of posterior wall fibroid. Laparotomy revealed a parasitic fibroid densely adherent to the omentum and extending retroperitoneally. Histopathological findings were consistent with leiomyoma