6 research outputs found

    Approaches for semantic interoperability between domain ontologies

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    Domain ontologies and knowledge-based systems have become very important in the agent and semantic web communities. As their use has increased, providing means of resolving semantic differences has also become very important. In this paper we survey the approaches that have been proposed for providing interoperability among domain ontologies. We also discuss some key issues that still need to be addressed if we are to move from semi-automated to fully automated approaches to providing consensus among heterogeneous ontologies.18 page(s

    DASMAS : dialogue based automation of semantic interoperability in multi agent systems

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    This paper presents our ongoing effort on developing a dialogue based framework for resolving semantic interoperability in multi agent systems. Our approach is characterized by: (1) multi agent systems that have real world heterogeneous ontologies; (2) the resolution of semantic differences at run-time through an adapted ontology negotiation protocol (ONP); and (3) the use of the Word Net lexicon in the resolution process.8 page(s

    Regeneration of periodontal ligament fibers around mini dental implants and their attachment to the bone in an animal model: A radiographic and histological study

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    Background: Tissue-engineered periodontal ligament (PDL) around a dental implant by using PDL stem cells (PDLSCs) may be useful in periodontal regeneration and can reduce or eliminate certain shortcomings of dental implants. Materials and Methods: PDLSCs were isolated from extracted human PDL cells and cultured in a bioreactor. They were identified using markers CD45, CD73, CD90, CD105, and CD146. After the formation of multiple cellular layers, they were then attached on titanium mini dental implants and placed in rabbit tibia. The rabbits were sacrificed after 9 months, and the implants were analyzed histologically and radiographically by Cone beam computed tomography (CBCT). Results: Isolated PDLSCs obtained from human premolars showed a colony-forming ability on the 7th day and 14th day. Immunocytochemistry revealed that cells had taken up the adequate positive stains for primary antibodies CD73, CD90, CD105, and CD146 and negative staining for CD45. The histological sections obtained from sacrificed rabbits, when viewed under the light microscope, clearly showed the presence of PDL around dental implants. CBCT examination showed that the implant was well within the bone and did not migrate. The site appeared to be normal without any lytic changes in the bone. Conclusion: It can safely be postulated from the present study that tissue engineering of PDL can be achieved around dental implants using PDLSCs. Important inter-tissue interactions like the formation of a functional PDL around the implantation site, and induction of bone formation in the vicinity of the implants may be possible. Future research in humans is required for further research
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