12 research outputs found
Small Molecule Inhibitors of West Nile Virus
No full textWest Nile virus is a human pathogen which is rapidly expanding worldwide. It is a member of the Flavivirus genus and it is transmitted by mosquitos between its avian hosts and occasionally in vertebrate hosts. In humans, the infection is often asymptomatic, but the most severe cases result in encephalitis or meningitis. Around 10% of cases of neuroinvasive disease are fatal. To date there is no effective human vaccine or effective antiviral therapy available to treat WNV infections For this reason, research in this field is rapidly growing. In this article we will review the latest efforts in the design and development of novel WNV inhibitors from a medicinal chemistry point of view, highlighting challenges and opportunities for the researchers working in this field
Novel Flavanone Glucoside with Free Radical Scavenging Properties from Galium fissurense
No full textآثار الأنشطة البشرية على الخصائص الرسوبية والجيوكيميائية لخليج مباØØ« - شمال الغردقة ØŒ البØر الأØمر ØŒ مصر
No full textDidox and resveratrol sensitize colorectal cancer cells to doxorubicin via activating apoptosis and ameliorating P-glycoprotein activity
No full textThe Chemistry and Biological Activities of Natural Products from Northern African Plant Families: From Taccaceae to Zygophyllaceae
No full textMolecular Mimics of Classic P-Glycoprotein Inhibitors as Multidrug Resistance Suppressors and Their Synergistic Effect on Paclitaxel
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Comparative study of phytochemical profile between Ziziphus spina christi and Ziziphus lotus from Morocco
No full textIdentification and Quantification of Boeravinone-B in dry fruit extract of Boerhaavia diffusa Linn and in its Polyherbal Formulation
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