La figura del sabio en las narraciones hispanohebreas de los siglos XII y XIII.

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Los cuentos misóginos de Maimon Gallipapa

The literary features of the small work Ma’amar Miḏyěnê ’iššâ attributed to Maimon Gallipapa (14th century) are analysed in this paper, pointing out the relation between this work and the Minḥaṯ Yěhudâ de Yěhudah Ibn Šabbětay (12th-13th centuries), their agreements and discrepancies.Se exponen las características literarias de la obrita Ma’amar Miḏyěnê ’iššâ atribuida a Maimon Gallipapa (s. XIV) y se compara con el Minḥaṯ Yěhudâ de Yěhudah Ibn Šabbětay (ss. XII-XIII), señalando sus coincidencias y discrepancias

La narrativa hebrea medieval

El tema que vamos a tratar es el del estudio de las narraciones literarias hispanohebreas escritas en prosa rimada, tradiclonalmente conocidas con el nombre de maqámas. Pensamos que, aunque el estudio científico de estas narraciones tuvo sus inicios también entre las grandes figuras de la investigación judía de finales del siglo xix, principios del xx, la narrativa ha sido en cierto modo algo así como la «cenicienta» de la Literatura hispanohebrea, ya que realmente los estudios a ella dedicados ocupan un lugar minoritario en comparación con los miles de páginas que tratan por ejemplo sobre la poesía. Sin embargo, y gracias a la varita mágica de los actuales investigadores, el interés por el estudio de las narraciones hispanohebreas medievales se ha ido incrementando y se está poniendo de manifiesto en diversos lugares del mundo. Es posible, pues, que la narrativa ocupe al fin el relevante lugar que le corresponde en la corte maravillosa de la literatura hebrea medieval

Las versiones hebreas de Calila y Dimna.

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El tema del exilio en la poesía de Mošeh ibn 'Ezra'

The author studies Mosheh ibn Ezra's lamentation's poems ( שירי תלונה ), in which emerges the ability and the brilliance of the medieval poet in selecting the appropiate vocabulary and in creating the most suppressing images in order to describe his own experience of the exile .La autora ha seleccionado los poemas de queja  ( שירי תלונה ) de Mošeh ibn 'Ezra' para hacer un detenido estudio que resalta el virtuosismo y la brillantez con que el poeta medieval escoge el vocabulario más apropiado y las imágenes más sorprendentes para describir su propia experiencia del exilio

SARS-CoV-2 Omicron BA.1 variant breakthrough infections in nursing home residents after an homologous third dose of the Comirnaty® COVID-19 vaccine: Looking for correlates of protection

8 páginas, 2 figuras. Texto completo en PubMedCentral: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9348298/pdf/JMV-94-4216.pdfWe investigated whether peripheral blood levels of SARS-CoV-2 Spike (S) receptor binding domain antibodies (anti-RBD), neutralizing antibodies (NtAb) targeting Omicron S, and S-reactive-interferon (IFN)-γ-producing CD4+ and CD8+ T cells measured after a homologous booster dose (3D) with the Comirnaty® vaccine was associated with the likelihood of subsequent breakthrough infections due to the Omicron variant. An observational study including 146 nursing home residents (median age, 80 years; range, 66-99; 109 female) evaluated for an immunological response after 3D (at a median of 16 days). Anti-RBD total antibodies were measured by chemiluminescent immunoassay. NtAb were quantified by an Omicron S pseudotyped virus neutralization assay. SARS-CoV-2-S specific-IFNγ-producing CD4+ and CD8+ T cells were enumerated by whole-blood flow cytometry for intracellular cytokine staining. In total, 33/146 participants contracted breakthrough Omicron infection (symptomatic in 30/33) within 4 months after 3D. Anti-RBD antibody levels were comparable in infected and uninfected participants (21 123 vs. 24 723 BAU/ml; p = 0.34). Likewise, NtAb titers (reciprocal IC50 titer, 157 vs. 95; p = 0.32) and frequency of virus-reactive CD4+ (p = 0.82) and CD8+ (p = 0.91) T cells were similar across participants in both groups. anti-RBD antibody levels and NtAb titers estimated at around the time of infection were also comparable (3445 vs. 4345 BAU/ml; p = 0.59 and 188.5 vs. 88.9; p = 0.70, respectively). Having detectable NtAb against Omicron or SARS-CoV-2-S-reactive-IFNγ-producing CD4+ or CD8+ T cells after 3D was not correlated with increased protection from breakthrough infection (OR, 1.50; p = 0.54; OR, 0.0; p = 0.99 and OR 3.70; p = 0.23, respectively). None of the immune parameters evaluated herein, including NtAb titers against the Omicron variant, may reliably predict at the individual level the risk of contracting COVID-19 due to the Omicron variant in nursing home residents.Ignacio Torres (Río Hortega Contract; CM20/00090), Estela Giménez (Juan Rodés Contract, JR18/00053), and Eliseo Albert (Juan Rodés Contract; JR20/00011) hold contracts funded by the Carlos III Health Institute (cofinanced by the European Regional Development Fund, ERDF/FEDER). Ron Geller holds a Ramon y Cajal fellowship from the Spanish Ministerio de Economía y Competitividad (RYC‐2015‐17517). This study work was supported by Instituto de Salud Carlos III, Madrid, Spain (FIS, PI21/00563) to David Navarro, and by the European Commission NextGenerationEU fund (EU 2020/2094), through CSIC's Global Health Platform (PTI Salud Global) to Ron Geller.Peer reviewe

Menstrual and Reproductive Factors and Risk of Gastric and Colorectal Cancer in Spain

BACKGROUND: Sex hormones play a role in gastric cancer and colorectal cancer etiology, however, epidemiological evidence is inconsistent. This study examines the influence of menstrual and reproductive factors over the risk of both tumors. METHODS: In this case-control study 128 women with gastric cancer and 1293 controls, as well as 562 female and colorectal cancer cases and 1605 controls were recruited in 9 and 11 Spanish provinces, respectively. Population controls were frequency matched to cases by age and province. Demographic and reproductive data were directly surveyed by trained staff. The association with gastric, colon and rectal cancer was assessed using logistic and multinomial mixed regression models. RESULTS: Our results show an inverse association of age at first birth with gastric cancer risk (five-year trend: OR = 0.69; p-value = 0.006). Ever users of hormonal contraception presented a decreased risk of gastric (OR = 0.42; 95%CI = 0.26-0.69), colon (OR = 0.64; 95%CI = 0.48-0.86) and rectal cancer (OR = 0.61; 95%CI = 0.43-0.88). Postmenopausal women who used hormone replacement therapy showed a decreased risk of colon and rectal tumors. A significant interaction of educational level with parity and months of first child lactation was also observed. CONCLUSION: These findings suggest a protective role of exogenous hormones in gastric and colorectal cancer risk. The role of endogenous hormones remains unclear

Estado actual de los estudios sobre la narrativa hispanohebrea

La autora recorre las principales obras de la narrativa hispano-hebrea y resalta los temas fundamentales de la investigación actual: géneros narrativos, influencia de la maqāma arabe, estructuras literarias complejas y simples, colecciones. Una actualizada bibliografía cierra el trabajo.The author surveys the principal works of hispano-hebraic narrative and emphasizes the fundamental themes of present day research: narrative genres, the influence of arabic maqāma, complex and simple literary structures, collections. An up-to-day bibliography brings the work to a close