Calcium-permeable channels activated via guanine nucleotide-dependent mechanism in human carcinoma cells

AbstractPatch clamp experiments on human carcinoma A431 cells have revealed two types of Ca2+-permeable channels, the activity of which can be increased by the application of non-hydrolyzable analogues of GTP to the intracellular side of the membrane. With 105 mM Ca2+ in recording pipette at 30–33°C their unitary conductances (in pS) are 1.3 (SG-channels) and 2.4 (G-channels). G- and, possibly, SG-channels are activated from the extracellular side of the membrane with epidermal growth factor (EGF). The data are consistent with the hypothesis that both channels are activated via guanine nucleotide binding (G) proteins

The role of apical support and rectal mucosal prolapse excision in successful treatment of rectocele combined with perineum descending: short-term and follow-up results

The aim of the research was to improve the results of surgery treatment of posterior compartment of pelvic floor using abdominal sacrocolpopexy and stapled trance-anal resection (STARR

Berry Phase in Neutrino Oscillations

We study the Berry phase in neutrino oscillations for both Dirac and Majorana neutrinos. In order to have a Berry phase, the neutrino oscillations must occur in a varying medium, the neutrino-background interactions must depend on at least two independent densities, and also there must be CP violation if the neutrino interactions with matter are mediated only by the standard model W and Z boson exchanges which implies that there must be at least three generations of neutrinos. The CP violating Majorana phases do not play a role in generating a Berry phase. We show that a natural way to satisfy the conditions for the generation of a Berry phase is to have sterile neutrinos with active-sterile neutrino mixing, in which case at least two active and one sterile neutrinos are required. If there are additional new CP violating flavor changing interactions, it is also possible to have a non-zero Berry phase with just two generations.Comment: RevTex 16 pages, no figures, new discussions about sterile neutrino added,typos corrected and errors in references correcte

The advantages of the abdominal sacral colpopexy combined with stapled trance-anal resection of the rectal mucosal prolapse (STARR) for the surgical treament of perineum descending syndrome

The problem of pelvic organ prolapse in women is still actual, because of high frequency of this pathology. Several surgical techniques have been suggested for pelvic descending syndrome treatment. But a large number of complications, unsatisfactory anatomical and functional results of suggested methods force to look for other solutions of the proble

T-violation tests for relativity principles

We consider the implications of a violation of the equivalence principle or of Lorentz invariance in the neutrino sector for the T-asymmetry $\Delta P_T \equiv P(\nu_{\alpha} \to \nu_{\beta}) - P(\nu_{\beta} \to \nu_{\alpha})$ in a three-flavour framework. We find that additional mixing due to these mechanisms, while obeying all present bounds, can lead to a substantial enhancement, suppression, and/or sign change in $\Delta P_T$ for the preferred energies and baselines of a neutrino factory. This in turn allows for the possibility of improving existing constraints by several orders of magnitude.Comment: 2 pages; Talk given at the 4th NuFact '02 Workshop (Neutrino Factories Based On Muon Storage Rings), 1-6 Jul 2002, London, England; To appear in proceeding

On the Strategy for the Development of the Information Society of the Russian Federation for 2017-2030

The article defines the concept of the information society, considers the strategy of the development of the information society in the Russian Federation. In the main part, the state of the development of the information society in the Russian Federation was studied using international indices: the ICT development index, the network readiness index (NRI), the e-government development index (EGDI), the knowledge economy index. A cluster analysis of the state of the information society as a whole was also conducted. The conclusions give recommendations on the improvement of the system of indicators, the mechanism of working with it, and documents clarifying the Strategy for the Development of the Information Society in the Russian Federation for 2017-2030. This will allow increasing the values of individual ratings, as well as the common place of Russia in a single information space

Three-particle States in Nonrelativistic Four-fermion Model

On a nonrelativistic contact four-fermion model we have shown that the simple Lambda-cut-off prescription together with definite fine-tuning of the Lambda dependency of "bare"quantities lead to self-adjoint semi-bounded Hamiltonian in one-, two- and three-particle sectors. The fixed self-adjoint extension and exact solutions in two-particle sector completely define three-particle problem. The renormalized Faddeev equations for the bound states with Fredholm properties are obtained and analyzed.Comment: 9 pages, LaTex, no figure

Thermochemiluminescent peroxide crystals

Chemiluminescence, a process of transduction of energy stored within chemical bonds of ground-state reactants into light via high-energy excited intermediates, is known in solution, but has remained undetected in macroscopic crystalline solids. By detecting thermally induced chemiluminescence from centimeter-size crystals of an organic peroxide here we demonstrate direct transduction of heat into light by thermochemiluminescence of bulk crystals. Heating of crystals of lophine hydroperoxide to ~115 °C results in detectable emission of blue-green light with maximum at 530 nm with low chemiluminescent quantum yield [(2.1 ± 0.1) × 10 ‒7 E mol ‒1 ]. Spectral comparison of the thermochemiluminescence in the solid state and in solution revealed that the solid-state thermochemiluminescence of lophine peroxide is due to emission from deprotonated lophine. With selected 1,2-dioxetane, endoperoxide and aroyl peroxide we also establish that the thermochemiluminescence is common for crystalline peroxides, with the color of the emitted light varying from blue to green to red

Fluxes of atmospheric muons underwater depending on the small-x gluon density

The prompt muon contribution to the deep-sea atmospheric muon flux can serve as a tool for probing into the small-x feature of the gluon density inside of a nucleon, if the muon energy threshold could be lifted to 100 TeV. The prompt muon flux underwater is calculated taking into consideration predictions of recent charm production models in which the small-x behaviour of the gluon distribution is probed. We discuss the possibility of distinguishing the PQCD models of the charm production differing in the small-x exponent of the gluon distribution, in measurements of the muon flux at energies 10-100 TeV with neutrino telescopes.Comment: 9 pages, 4 eps figures, uses iopart.st