1 research outputs found
Arf3 Is Activated Uniquely at the trans-Golgi Network by Brefeldin A-inhibited Guanine Nucleotide Exchange Factors
Arf3 associates with the TGN in a manner that is both temperature-sensitive and uniquely dependent on BIGs. TGN localization and release at 20°C are readily separated and depend on pairs of residues absolutely conserved and unique to Arf3 present at opposite ends of the protein. These results suggest that Arf3 plays a unique function at the TGN