26 research outputs found
Diffusion in a Granular Fluid - Theory
Many important properties of granular fluids can be represented by a system
of hard spheres with inelastic collisions. Traditional methods of
nonequilibrium statistical mechanics are effective for analysis and description
of the inelastic case as well. This is illustrated here for diffusion of an
impurity particle in a fluid undergoing homogeneous cooling. An appropriate
scaling of the Liouville equation is described such that the homogeneous
cooling ensemble and associated time correlation functions map to those of a
stationary state. In this form the familiar methods of linear response can be
applied, leading to Green - Kubo and Einstein representations of diffusion in
terms of the velocity and mean square displacement correlation functions. These
correlation functions are evaluated approximately using a cumulant expansion
and from kinetic theory, providing the diffusion coefficient as a function of
the density and the restitution coefficients. Comparisons with results from
molecular dynamics simulation are given in the following companion paper
High Speed and High Efficiency Travelling Wave Single-Photon Detectors Embedded in Nanophotonic Circuits
Ultrafast, high quantum efficiency single photon detectors are among the most
sought-after elements in modern quantum optics and quantum communication. High
photon detection efficiency is essential for scalable measurement-based quantum
computation, quantum key distribution, and loophole-free Bell experiments.
However, imperfect modal matching and finite photon absorption rates have
usually limited the maximum attainable detection efficiency of single photon
detectors. Here we demonstrate a superconducting nanowire detector atop
nanophotonic waveguides which allows us to drastically increase the absorption
length for incoming photons. When operating the detectors close to the critical
current we achieve high on-chip single photon detection efficiency up to 91% at
telecom wavelengths, with uncertainty dictated by the variation of the
waveguide photon flux. We also observe remarkably low dark count rates without
significant compromise of detection efficiency. Furthermore, our detectors are
fully embedded in a scalable silicon photonic circuit and provide ultrashort
timing jitter of 18ps. Exploiting this high temporal resolution we demonstrate
ballistic photon transport in silicon ring resonators. The direct
implementation of such a detector with high quantum efficiency, high detection
speed and low jitter time on chip overcomes a major barrier in integrated
quantum photonics
Short Circuit Incipient Fault Detection and Supervision in a Three-Phase Induction Motor with a SOM-Based Algorithm
Simultaneous Determination of Ofloxacin and Ornidazole in Solid Dosage Form by RP-HPLC and HPTLC Techniques
The objective of this work was to develop and validate simple, rapid and accurate chromatographic methods for simultaneous determination of ofloxacin and ornidazole in solid dosage form. The first method was based on reversed phase high performance liquid chromatography, on Intersil C18 column (250 mm, 4.6 i.d.), using acetonitrile:methanol: 0.025M phosphate buffer, pH 3.0 (30:10:60 % v/v/v) as the mobile phase, at a flow rate of 1 ml/min at ambient temperature. Quantification was achieved with UV detection at 318 nm over a concentration range of 2-40 µg/ml for ofloxacin and 5-100 µg/ml for ornidazole. The mean retention time of ofloxacin and ornidazole was found to be 4.04 min and 5.83 min, 6.77 min (isomers), respectively. The amount of ofloxacin and ornidazole estimated as percentage of label claimed was found to be 100.23 and 99.61%, with mean percent recoveries 100.20 and 100.93%, respectively. The second method was based on TLC separation of these drugs using silica gel 60F254 aluminium sheets and dichloromethane:methanol:25% ammonia solution (9.5:1:3 drops v/v) as mobile phase. Detection was carried out at 318 nm over the concentration range of 20-100 ng/spot for ofloxacin and 50-250 ng/spot for ornidazole. The mean Rf value of ofloxacin and ornidazole was found to be 0.16 and 0.56, 0.78 (isomers), respectively. The amount of ofloxacin and ornidazole estimated as percentage of label claimed was found to be 100.23 and 99.61% with mean percent recoveries 100.47 and 99.32%, respectively. Both these methods were found to be simple, precise, accurate, selective and rapid and could be successfully applied for the determination of pure laboratory prepared mixtures and tablets
Retinal vasculitis with Chronic Recurrent Multifocal Osteomyelitis: A case report and review of the literature
© The Author(s). 2019 Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated. Background: Concurrent presentation of retinal vasculitis with mixed sclerotic and lytic bone lesions is rare. Case presentation: We present the case of a 37-year old woman with a several year history of episodic sternoclavicular pain who presented for rheumatologic evaluation due to a recent diagnosis of retinal vasculitis. We review the differential diagnosis of retinal vasculitis, along with the differential diagnosis of mixed sclerotic and lytic bone lesions. Ultimately, bone marrow biopsy confirmed diagnosis of chronic recurrent multifocal osteomyelitis (CRMO) . Concurrent presentation of CRMO with retinal vasculitis is extremely rare but important to recognize. The patient demonstrated clinical response to prednisone and tumor necrosis factor-alpha inhibition (TNF-i). Conclusion: This case reports and unusual presentation of CRMO spectrum disease involving the sternum and sternoclavicular joint with concurrent retinal vasculitis
Retinal vasculitis with Chronic Recurrent Multifocal Osteomyelitis: a case report and review of the literature.
Background: Concurrent presentation of retinal vasculitis with mixed sclerotic and lytic bone lesions is rare.
Case presentation: We present the case of a 37-year old woman with a several year history of episodic sternoclavicular pain who presented for rheumatologic evaluation due to a recent diagnosis of retinal vasculitis. We review the differential diagnosis of retinal vasculitis, along with the differential diagnosis of mixed sclerotic and lytic bone lesions. Ultimately, bone marrow biopsy confirmed diagnosis of chronic recurrent multifocal osteomyelitis (CRMO). Concurrent presentation of CRMO with retinal vasculitis is extremely rare but important to recognize. The patient demonstrated clinical response to prednisone and tumor necrosis factor-alpha inhibition (TNF-i).
Conclusion: This case reports and unusual presentation of CRMO spectrum disease involving the sternum and sternoclavicular joint with concurrent retinal vasculitis