Life of Tamil Peoples in Kuruntokai

The Sangam Age is the first period in the history of Tamil literature. Sangam literature is a clear mirror of the life style of the people who lived in the Sangam Age. The Sangam literature also contains references to the customs, beliefs, trade practices, royal character, marriage practices, etc. of the society of the time. Many truths sung in Sangam literature have conquered time and space and are eternal truths. Tamils have lived their lives happily through Kuruntokai. Especially in domestic life, there was an understanding and a maturity of compromise. It is also known that they have lived by the principles of hospitality, material pursuit, and immeasurable love

Observation of persistent flow of a Bose-Einstein condensate in a toroidal trap

We have observed the persistent flow of Bose-condensed atoms in a toroidal trap. The flow persists without decay for up to 10 s, limited only by experimental factors such as drift and trap lifetime. The quantized rotation was initiated by transferring one unit, $\hbar$, of the orbital angular momentum from Laguerre-Gaussian photons to each atom. Stable flow was only possible when the trap was multiply-connected, and was observed with a BEC fraction as small as 15%. We also created flow with two units of angular momentum, and observed its splitting into two singly-charged vortices when the trap geometry was changed from multiply- to simply-connected.Comment: 1 file, 5 figure

Major Galaxy Mergers and the Growth of Supermassive Black Holes in Quasars

Despite observed strong correlations between central supermassive black holes (SMBHs) and star-formation in galactic nuclei, uncertainties exist in our understanding of their coupling. We present observations of the ratio of heavily-obscured to unobscured quasars as a function of cosmic epoch up to z~3, and show that a simple physical model describing mergers of massive, gas-rich galaxies matches these observations. In the context of this model, every obscured and unobscured quasar represent two distinct phases that result from a massive galaxy merger event. Much of the mass growth of the SMBH occurs during the heavily-obscured phase. These observations provide additional evidence for a causal link between gas-rich galaxy mergers, accretion onto the nuclear SMBH and coeval star formation.Comment: Accepted for publication in Science. Published by Science Express on March 25th. 17 pages, 5 figures, including supplemental online materia

Characterizing the Cluster Lens Population

We present a detailed investigation into which properties of CDM halos make them effective strong gravitational lenses. Strong lensing cross sections of 878 clusters from an N-body simulation are measured by ray tracing through 13,594 unique projections. We measure concentrations, axis ratios, orientations, and the amount of substructure of each cluster, and compare the lensing weighted distribution of each quantity to that of the cluster population as a whole. The concentrations of lensing clusters are on average 34% larger than the typical cluster in the Universe. Despite this bias, the anomalously high concentrations (c >14) recently measured by several groups, appear to be inconsistent with the concentration distribution in our simulations, which predict < 2% of lensing clusters should have concentrations this high. No correlation is found between lensing cross section and the amount of substructure. We introduce several types of simplified dark matter halos, and use them to isolate which properties of CDM clusters make them effective lenses. Projections of halo substructure onto small radii and the large scale mass distribution of clusters do not significantly influence cross sections. The abundance of giant arcs is primarily determined by the mass distribution within an average overdensity of ~ 10,000. A multiple lens plane ray tracing algorithm is used to show that projections of large scale structure increase the giant arc abundance by a modest amount <7%. We revisit the question of whether there is an excess of giant arcs behind high redshift clusters in the RCS survey and find that the number of high redshift (z > 0.6) lenses is in good agreement with LCDM, although our simulations predict more low redshift (z < 0.6) lenses than were observed. (abridged)Comment: 19 pages, 15 figures. Submitted to Ap

A three-dimensional open-framework tin(II) phosphate exhibiting reversible dehydration and ion-exchange properties

A three-dimensional open-framework tin(II) phosphate, prepared hydrothermally with 1,3-diaminopentane as the template, is shown to exhibit reversible dehydration and ion-exchange properties

Constraining the Collisional Nature of the Dark Matter Through Observations of Gravitational Wakes

We propose to use gravitational wakes as a direct observational probe of the collisional nature of the dark matter. We calculate analytically the structure of a wake generated by the motion of a galaxy in the core of an X-ray cluster for dark matter in the highly-collisional and collisionless limits. We show that the difference between these limits can be recovered from detailed X-ray or weak lensing observations. We also discuss the sizes of sub-halos in these limits. Preliminary X-ray data on the motion of NGC 1404 through the Fornax group disfavors fluid-like dark matter but does not exclude scenarios in which the dark matter is weakly collisional.Comment: 29 pages, 3 figures, submitted to Ap

Observation of sub-natural linewidths for cold atoms in a magneto-optic trap

We have studied the absorption of a weak probe beam through cold rubidium atoms in a magneto-optic trap. The absorption spectrum shows two peaks with the smaller peak having linewidth as small as 28% of the natural linewidth. The modification happens because the laser beams used for trapping also drive the atoms coherently between the ground and excited states. This creates ``dressed'' states whose energies are shifted depending on the strength of the drive. Linewidth narrowing occurs due to quantum coherence between the dressed states. The separation of the states increases with laser intensity and detuning, as expected from this model.Comment: 8 pages, 4 figure

Impact of COVID-19 on stroke admissions, treatments, and outcomes at a comprehensive stroke centre in the United Kingdom

Introduction The coronavirus disease (COVID-19) pandemic has changed routine clinical practice worldwide with major impacts on the provision of care and treatment for stroke patients. Methods This retrospective observational study included all patients admitted to the Royal Stoke University Hospital in Stokeon-Trent, UK, with a stroke or transient ischaemic attack between March 15th and April 14th, 2020 (COVID). Patient demographics, characteristics of the stroke, treatment details and logistics were compared with patients admitted in the corresponding weeks in the year before (2019). Results There was a 39.5% (n = 101 vs n = 167) reduction in admissions in the COVID cohort compared with 2019 with more severe strokes (median National Institutes of Health Stroke Scale (NIHSS) 7 vs 4, p = 0.02), and fewer strokes with no visible acute pathology (21.8 vs 37.1%, p = 0.01) on computed tomography. There was no statistically significant difference in the rates of thrombolysis (10.9 vs 13.2%, p = 0.72) and/or thrombectomy (5.9 vs 4.8%, p = 0.90) and no statistically significant difference in time from stroke onset to arrival at hospital (734 vs 576 min, p = 0.34), door-to-needle time for thrombolysis (54 vs 64 min, p = 0.43) and door-to-thrombectomy time (181 vs 445 min, p = 0.72). Thirty-day mortality was not significantly higher in the COVID year (10.9 vs 8.9%, p = 0.77). None of the 7 stroke patients infected with COVID-19 died. Conclusions During the COVID-19 pandemic, the number of stroke admissions fell, and stroke severity increased. There was no statistically significant change in the delivery of thrombolysis and mechanical thrombectomy and no increase in mortality

Ascorbate-dependent vasopressor synthesis: a rationale for vitamin C administration in severe sepsis and septic shock?

Severe systemic inflammatory response to infection results in severe sepsis and septic shock, which are the leading causes of death in critically ill patients. Septic shock is characterised by refractory hypotension and is typically managed by fluid resuscitation and administration of catecholamine vasopressors such as norepinephrine. Vasopressin can also be administered to raise mean arterial pressure or decrease the norepinephrine dose. Endogenous norepinephrine and vasopressin are synthesised by the copper-containing enzymes dopamine β-hydroxylase and peptidylglycine α-amidating monooxygenase, respectively. Both of these enzymes require ascorbate as a cofactor for optimal activity. Patients with severe sepsis present with hypovitaminosis C, and pre-clinical and clinical studies have indicated that administration of high-dose ascorbate decreases the levels of pro-inflammatory biomarkers, attenuates organ dysfunction and improves haemodynamic parameters. It is conceivable that administration of ascorbate to septic patients with hypovitaminosis C could improve endogenous vasopressor synthesis and thus ameliorate the requirement for exogenously administered vasopressors. Ascorbate-dependent vasopressor synthesis represents a currently underexplored biochemical mechanism by which ascorbate could act as an adjuvant therapy for severe sepsis and septic shock