Prevención de Enfermedades Transmitidas por Alimentos: Aislamiento de Salmonella spp., E. coli O157:H7 y E. coli productor de Toxina Shiga (STEC) no O157 en el proceso de elaboración de carne molida fresca destinada a consumo minorista

El objetivo general del estudio fue determinar la calidad microbiológica de la carne molida fresca procesada comercializada en Asunción destinada al consumo minorista; e implementar acciones de prevención y control para prevenir Enfermedades Transmitidas por Alimentos (ETA) asociadas al consumo de carne.CONACYT - Consejo Nacional de Ciencias y TecnologíaPROCIENCI

Tele-microscopy system based on mobile telephone for distance diagnosis of tuberculosis in remote areas of Paraguay

Tuberculosis remains a major public health problem in Paraguay. Diagnosis and monitoring of treatment are based mainly on bacilloscopy (examination of a sputum smear to verify the presence of specific bacilli). This test can be carried out in a laboratory with minimal resources such as Zichl Neelsen reagents and a microscope. Most of the primary care centers in Paraguay have these resources.CONACYT – Consejo Nacional de Ciencia y TecnologíaPROCIENCI

Phylogeography and transmission of Mycobacterium tuberculosis spanning prisons and surrounding communities in Paraguay

To role that carceral institutions play in Mycobacterium tuberculosis transmission remains somewhat unknown. Authors perform a prospective genomic surveillance study, to assess transmission dynamics in prisons and surrounding communities in Paraguay

Whole genomes from bacteria collected at diagnostic units around the world 2020

Abstract The Two Weeks in the World research project has resulted in a dataset of 3087 clinically relevant bacterial genomes with pertaining metadata, collected from 59 diagnostic units in 35 countries around the world during 2020. A relational database is available with metadata and summary data from selected bioinformatic analysis, such as species prediction and identification of acquired resistance genes

Genomic analysis of sewage from 101 countries reveals global landscape of antimicrobial resistance

Antimicrobial resistance (AMR) is a major threat to global health. Understanding the emergence, evolution, and transmission of individual antibiotic resistance genes (ARGs) is essential to develop sustainable strategies combatting this threat. Here, we use metagenomic sequencing to analyse ARGs in 757 sewage samples from 243 cities in 101 countries, collected from 2016 to 2019. We find regional patterns in resistomes, and these differ between subsets corresponding to drug classes and are partly driven by taxonomic variation. The genetic environments of 49 common ARGs are highly diverse, with most common ARGs carried by multiple distinct genomic contexts globally and sometimes on plasmids. Analysis of flanking sequence revealed ARG-specific patterns of dispersal limitation and global transmission. Our data furthermore suggest certain geographies are more prone to transmission events and should receive additional attention