1,717 research outputs found
Evaluation of quality assurance instruments in higher education institutions: A case of Oman
The use of a variety of instruments for quality assurance, management, and enhancement in higher education is well recognized. This article investigated the instruClose Panelments used by Higher Education Institutions (HEIs) in Oman to measure, control, and manage the quality of their services in alignment with the standards set by Oman Academic Accreditation Authority (OAAA). Quality Assurance Managers (QAMs) from five HEIs were interviewed to identify the instruments used by them to fulfil the requirements of each standard and the way they make use of the data gathered by using these instruments. Findings from the study reveal that questionnaires and meetings are the most common instruments used by these institutions to measure, control and assure the efficacy of their current quality activities. In addition, HEIs use summary statistics to analyse data and then present them in meetings or through reports. On the other hand, it was found that substantial efforts are made to collect data but the efficient usage of data is missing. The QAMs reported a lack of awareness among the staff on the importance of collecting data since the staff members believe that these data are collected for documentation purposes only. This study emphasizes the importance of using the data gathered from different instruments in decision making and enhancing the quality of HEIs
Cilostazol versus aspirin for secondary prevention of vascular events after stroke of arterial origin
Background:Aspirin is widely used for secondary prevention after stroke. Cilostazol has shown promise as an alternative to aspirin in Asian people with stroke. ObjectiveS: To determine the relative effectiveness and safety of cilostazol compared directly with aspirin in the prevention of stroke and other serious vascular events in Patients at high vascular risk for subsequent stroke, those with previous transient ischaemic attack (TIA) or ischaemic stroke of arterial origin. SEARCH STRATEGY: We searched the Cochrane Stroke Group Trials Register (last searched September 2010), the Cochrane Central Register of Controlled Trials (CENTRAL) (The Cochrane Library 2009, Issue 4), MEDLINE (1950 to May 2010) and EMBASE (1980 to May 2010). In an effort to identify further published, ongoing and unpublished studies we searched journals, conference proceedings and ongoing trial registers, scanned reference lists from relevant studies and contacted trialists and Otsuka Pharmaceutical Co Ltd. SELECTION CRITERIA: We selected all randomised controlled trials (RCTs) comparing cilostazol with aspirin where participants were treated for at least one month and followed systematically for development of vascular events. DATA COLLECTION and ANALYSIS: Data extracted from eligible studies included: (1) a composite outcome of vascular events (stroke, myocardial infarction or vascular death) during follow up (primary outcome), (2) separate outcomes of stroke (ischaemic or haemorrhagic, fatal or non-fatal), myocardial infarction (MI) (fatal or non-fatal), vascular death and death from all causes, and (3) main outcomes of safety including any intracranial, extracranial or gastrointestinal (GI) haemorrhage and other outcomes during treatment follow up (secondary outcomes). We computed an estimate of treatment effect and performed a test for heterogeneity between trials. We analysed data on an intention-to-treat basis and assessed bias for all included studies. MAIN
Results:
We included two RCTs with 3477 Asian participants. Compared with aspirin, cilostazol was associated with a significantly lower risk of composite outcome of vascular events (6.77% versus 9.39%, risk ratio (RR) 0.72, 95% confidence interval (CI) 0.57 to 0.91), and lower risk of haemorrhagic stroke (0.53% versus 2.01%, RR 0.26, 95% CI 0.13 to 0.55). In terms of outcome of safety compared with aspirin, cilostazol was significantly associated with minor adverse effects (8.22% versus 4.95%, RR 1.66, 95% CI 1.51 to 1.83). AUTHORS\u27 Conclusions: Cilostazol is more effective than aspirin in the prevention of vascular events secondary to stroke. Cilostazol has more minor adverse effects, although there is evidence of fewer bleeds
Nitrous oxide emissions from the Arabian Sea: A synthesis
We computed high-resolution (1º latitude x 1º longitude) seasonal and annual nitrous oxide (N2O) concentration fields for the Arabian Sea surface layer using a database containing more than 2400 values measured between December 1977 and July 1997. N2O concentrations are highest during the southwest (SW) monsoon along the southern Indian continental shelf. Annual emissions range from 0.33 to 0.70 Tg N2O and are dominated by fluxes from coastal regions during the SW and northeast monsoons. Our revised estimate for the annual N2O flux from the Arabian Sea is much more tightly constrained than the previous consensus derived using averaged in-situ data from a smaller number of studies. However, the tendency to focus on measurements in locally restricted features in combination with insufficient seasonal data coverage leads to considerable uncertainties of the concentration fields and thus in the flux estimates, especially in the coastal zones of the northern and eastern Arabian Sea. The overall mean relative error of the annual N2O emissions from the Arabian Sea was estimated to be at least 65%
The problem of choice
Convictions are a driving force for actions. Considering that every individual has a different set of convictions and larger groups act once a consensus decision is reached, one can see that debate is an inherent exercise in decision-making. This requires a sustainably generated surplus to allow time for intellectual exchange, gathering of information and dissemination of findings. It is essential that the full spectrum of options remain treated equally. At the end of this process, a choice has to be made. Looking back at a later time point, a retrospective analysis sometimes reveals that the choice was neither completely free nor a truly conscious one. Leaving the issue of consequences of a once made decision aside, we wish to contribute to the debate of the problem of choice
Novel technique for constraining r-process (n,) reaction rates
A novel technique has been developed, which will open exciting new
opportunities for studying the very neutron-rich nuclei involved in the
r-process. As a proof-of-principle, the -spectra from the -decay
of Ga have been measured with the SuN detector at the National
Superconducting Cyclotron Laboratory. The nuclear level density and
-ray strength function are extracted and used as input to
Hauser-Feshbach calculations. The present technique is shown to strongly
constrain the Ge()Ge cross section and reaction rate.Comment: 5 pages, 3 figure
Inter-band B(E2) transition strengths in odd-mass heavy deformed nuclei
Inter-band B(E2) transition strengths between different normal parity bands
in 163Dy and 165Er are described using the pseudo-SU(3) model. The Hamiltonian
includes Nilsson single-particle energies, quadrupole-quadrupole and pairing
interactions with fixed, parametrized strengths, and three extra rotor terms
used to fine tune the energy spectra. In addition to inter-band transitions,
the energy spectra and the ground state intra-band B(E2) strengths are
reported. The results show the pseudo-SU(3) shell model to be a powerful
microscopic theory for a description of the normal parity sector in heavy
deformed odd-A nuclei.Comment: 4 figures, 2 table
A Note on Mirror Symmetry for Manifolds with Spin(7) Holonomy
Starting from the superconformal algebras associated with manifolds, I
extend the algebra to the manifolds with spin(7) holonomy. I show how the
mirror symmetry in manifolds with spin(7) holonomy arises as the automorphism
in the extended sperconformal algebra. The automorphism is realized as 14 kinds
of T-dualities on the supersymmetric toroidal fibrations. One class of
Joyce's orbifolds are pairwise identified under the symmetry.Comment: 12 pages, harvmac bi
Fluctuations in productivity and denitrification in the Southeastern Arabian Sea during the Late Quaternary
Sedimentological and stable isotopic characteristics of sediments have been studied in a core from the
southeastern Arabian Sea containing records of the past 70 ka. Palaeoproductivity proxies such as organic carbon
(Corg), total nitrogen (TN) and calcium carbonate (CaCO3) contents, show high values at the core top
and during the Last Glacial Maximum (LGM) and marine isotope stage (MIS) 4, suggesting high productivity, whereas low
Corg and CaCO3 contents are associated with the MIS ½ and mid-MIS 3, indicating reduced
productivity. The δ18O values in planktonic foraminifera range between - 2.7% and - 0.1%, with a large
glacial-interglacial amplitude Δδ18O of ∼2.6%, suggesting changes related to monsoonal
precipitation/ runoff. The δ15N values fluctuate between 5.4% and 7.3%, signifying variation in
denitrification intensity. The δ15N indicates an overall increase in denitrification intensity during MIS 1
and MIS 3 and, reduced intensity during MIS ½, LGM and mid-MIS 3. Higher primary productivity and reduced
denitrification intensity during LGM and MIS 4 might be due to convective winter mixing and more oxygenated subsurface
waters. Reduced primary productivity during MIS ½ and mid-MIS 3 might be the effect of enhanced precipitation
associated with the intensified southwest monsoon fortifying near-surface stratification
Prescription pattern of benzodiazepines for inpatients at a tertiary care university hospital in Pakistan
Objective: To determine the point prevalence of benzodiazepine prescriptions for inpatients at a tertiary care university hospital in Pakistan and to correlate it with prescription patterns of various specialties, indications and demographic variables of the patients.Methods: This 24-hours point prevalence study was done at The Aga Khan University Hospital, Karachi. By convenient random sampling, 208 inpatients were interviewed. Patients\u27 files were also studied to record the drugs administered. Data was entered into questionnaires and analyzed by SPSS 10.0.Results: The point prevalence of the benzodiazepines was 21.2%. It was higher among males than females and among surgical than non-surgical patients. Midazolam was the most commonly used benzodiazepine, followed by Alprazolam and Lorazepam. Pre-anesthesia and psychiatric symptoms were the two most common indications. Oral route was used in 84% patients for drug administration and mean Valium equivalent dosage was 4.86 mg/day. Mean length of prescription was 3 days. Longer duration of hospitalization was a significant predictor of the requirement of benzodiazepine prescription (p-value = 0.020).CONCLUSION: Prescription pattern of benzodiazepines at a tertiary care university hospital is similar to that reported in the developed countries through monitoring at various levels by physicians, clinical pharmacist and nursing staff. Data regarding the prescription pattern of benzodiazepines is scarce, and it needs to be expanded to formulate clear guidelines regarding their prescription
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