Comparing technical efficiency of organic and conventional coffee farms in Nepal using data envelopment analysis (DEA) approach

Data Envelopment Analysis (DEA) approach used to estimate technical efficiency and followed by regressing the technical efficiency scores to farm specific characters under tobit regression model. Primary data was collected from random samples of 240 (120 from each) coffee famers. Mean technical efficiency score was 0.89 and 0.83 in organic and conventional coffee farming respectively. Farms operating under CRS, DRS and IRS were 31.67, 3.83 and 37.5% respectively in organic coffee and 29.17, 25 and 45.83% respectively in conventional farming areas. Tobit regression showed the variation in technical efficiency was related education, farm experience and training/extension services and excess to credit.Production frontier, Resource use, Technical efficiency, Organic, Altitude, Productivity Analysis,

Intrinsic vs. extrinsic anomalous Hall effect in ferromagnets

A unified theory of the anomalous Hall effect (AHE) is presented for multi-band ferromagnetic metallic systems with dilute impurities. In the clean limit, the AHE is mostly due to the extrinsic skew-scattering. When the Fermi level is located around anti-crossing of band dispersions split by spin-orbit interaction, the intrinsic AHE to be calculated ab initio is resonantly enhanced by its non-perturbative nature, revealing the extrinsic-to-intrinsic crossover which occurs when the relaxation rate is comparable to the spin-orbit interaction energy.Comment: 5 pages including 4 figures, RevTex; minor changes, to appaer in Phys. Rev. Let

Spin Hall effect of conserved current: Conditions for a nonzero spin Hall current

We study the spin Hall effect taking into account the impurity scattering effect as general as possible with the focus on the definition of the spin current. The conserved bulk spin current (Shi et al. [Phys. Rev. Lett. 96, 076604 (2006)]) satisfying the continuity equation of spin is considered in addition to the conventional one defined by the symmetric product of the spin and velocity operators. Conditions for non-zero spin Hall current are clarified. In particular, it is found that (i) the spin Hall current is non-zero in the Rashba model with a finite-range impurity potential, and (ii) the spin Hall current vanishes in the cubic Rashba model with a $\delta$-function impurity potential.Comment: 5 pages, minor change from the previous versio

HybGFS: a hybrid method for genome-fingerprint scanning

BACKGROUND: Protein identification based on mass spectrometry (MS) has previously been performed using peptide mass fingerprinting (PMF) or tandem MS (MS/MS) database searching. However, these methods cannot identify proteins that are not already listed in existing databases. Moreover, the alternative approach of de novo sequencing requires costly equipment and the interpretation of complex MS/MS spectra. Thus, there is a need for novel high-throughput protein-identification methods that are independent of existing predefined protein databases. RESULTS: Here, we present a hybrid method for genome-fingerprint scanning, known as HybGFS. This technique combines genome sequence-based peptide MS/MS ion searching with liquid-chromatography elution-time (LC-ET) prediction, to improve the reliability of identification. The hybrid method allows the simultaneous identification and mapping of proteins without a priori information about their coding sequences. The current study used standard LC-MS/MS data to query an in silico-generated six-reading-frame translation and the enzymatic digest of an entire genome. Used in conjunction with precursor/product ion-mass searching, the LC-ETs increased confidence in the peptide-identification process and reduced the number of false-positive matches. The power of this method was demonstrated using recombinant proteins from the Escherichia coli K12 strain. CONCLUSION: The novel hybrid method described in this study will be useful for the large-scale experimental confirmation of genome coding sequences, without the need for transcriptome-level expression analysis or costly MS database searching

Promoter-Level Transcriptome Identifies Stemness Associated With Relatively High Proliferation in Pancreatic Cancer Cells

Both pancreatic intraepithelial neoplasia (PanIN), a frequent precursor of pancreatic cancer, and intraductal papillary mucinous neoplasm (IPMN), a less common precursor, undergo several phases of molecular conversions and finally develop into highly malignant solid tumors with negative effects on the quality of life. We approached this long-standing issue by examining the following PanIN/IPMN cell lines derived from mouse models of pancreatic cancer: Ptf1a-Cre; KrasG12D; p53f/+ and Ptf1a-Cre; KrasG12D; and Brg1f/f pancreatic ductal adenocarcinomas (PDAs). The mRNA from these cells was subjected to a cap analysis of gene expression (CAGE) to map the transcription starting sites and quantify the expression of promoters across the genome. Two RNA samples extracted from three individual subcutaneous tumors generated by the transplantation of PanIN or IPMN cancer cell lines were used to generate libraries and Illumina Seq, with four RNA samples in total, to depict discrete transcriptional network between IPMN and PanIN. Moreover, in IPMN cells, the transcriptome tended to be enriched for suppressive and inhibitory biological processes. In contrast, the transcriptome of PanIN cells exhibited properties of stemness. Notably, the proliferation capacity of the latter cells in culture was only minimally constrained by well-known chemotherapy drugs such as GSK690693 and gemcitabine. The various transcriptional factor network systems detected in PanIN and IPMN cells reflect the distinct molecular profiles of these cell types. Further, we hope that these findings will enhance our mechanistic understanding of the characteristic molecular alterations underlying pancreatic cancer precursors. These data may provide a promising direction for therapeutic research

Field-induced metal-insulator transition and switching phenomenon in correlated insulators

We study the nonequilibrium switching phenomenon associated with the metal-insulator transition under electric field E in correlated insulator by a gauge-covariant Keldysh formalism. Due to the feedback effect of the resistive current I, this occurs as a first-order transition with a hysteresis of I-V characteristics having a lower threshold electric field (\sim 10^4 Vcm^{-1}) much weaker than that for the Zener breakdown. It is also found that the localized mid-gap states introduced by impurities and defects act as hot spots across which the resonant tunneling occurs selectively, which leads to the conductive filamentary paths and reduces the energy cost of the switching function.Comment: 5 pages, 3 figures. A study on the metal-insulator transition in correlated insulators was adde