Brand Engagement in Virtual Communities – A Netnographic Study

Social media groups help foster discussions, but it can be challenging for brands to maintain user engagement and collaborate in value co-creation. Despite a pressing need to comprehend the dynamics of virtual communities, there is a lack of a concerted view of how users engage with brands in virtual communities. To explore this, we use a sport-based virtual community as context since fan engagement levels are substantially higher in sports communities than in other virtual communities. Leveraging the sense of community theory and netnography as a method, we study community formation in a Facebook group comprising fans of a European football club. Preliminary findings reveal a strong presence of membership, influence, and shared emotional connection, while integration and fulfillment of needs are relatively less dominant. As next steps, we plan to examine how a sense of community evolves in virtual communities through a longitudinal approach. Potential implications are discussed

Cerium(III) Chloride: A Highly Efficient Reagent for the Synthesis of α‐Aminonitriles

We report a highly efficient, one‐pot, three‐component condensation of carbonyl compounds, amines, and TMSCN in MeCN; the reaction is significantly promoted by the catalytic amount of cerium(III) chloride at ambient temperature in excellent yields without any adverse effect on the other substituents. The method afforded an elegant alternative to the synthesis of α‐aminonitriles. The reactions are fast and clean, and the products obtained are of high purity

ChemInform Abstract: Rapid, Chemoselective and Facile Synthesis of Azines by Hydrazine/I2.

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option

Regioselective synthesis of 1,5-disubstituted 1,2,3-triazoles by reusable AlCl₃ immobilized on ϒ-Aɭ₂O₃

Abstract: There is rapidly growing interest in the synthesis and use of substituted 1,2,3- triazoles. We report an easy and interesting procedure that demonstrates the effectiveness of surface-modified c-Al2O3, which is reusable, efficient, catalytic, safe, and environmentally acceptable for the regioselective synthesis of 1,5-disubstituted-1,2,3- triazoles via [3þ2] cycloaddition of phenyl and benzyl azides with a series of aryl nitroolefins in good yields. No adverse effect on substituents such as nitro, cyano, hydroxy, ether linkage, and halogens was observed. The catalyst could easily be recycled and was reused for nine runs without losing its activity

Is Nomophobia an Early Indicator of Developing Problematic Smartphone Use?

Problematic smartphone use and nomophobia have been associated with several psychopathological conditions. However, little is known about the interconnectedness of these phenomena and conditions that influence them, despite previous studies discussing the mediating effects of variables such as boredom proneness, self-control, and attachment anxiety. We differentiate them as separate phenomena and investigate the role of emotional wellbeing and mindfulness in influencing them through a quantitative study with a sample of 282 participants. Statistical analysis shows that negative affective states indirectly influence problematic smartphone use through nomophobia while gender and occupation have an impact of nomophobia as well. Further, mindfulness has no bearing on problematic smartphone use or nomophobia. The study demonstrates subtle differences between two dark side phenomena and signifies the varying effects on them. It furthers the argument that dark side phenomena are interrelated and highlights the need to explore mitigation mechanisms beyond mindfulness to deal with these phenomena

A comparative study of ondansetron and granisetron in combination with dexamethasone-in prophylaxis for postoperative nausea and vomiting (PONV) in laproscopic cholecystectomies

Background: Post operative nausea and vomiting (PONV) is a common problem and distressing symptom in surgical patient population. General anaesthesia with inhalational agents is associated with an average PONV incidence of 20-30 % in surgical patients. PONV is difficult to treat and needs multiple drugs and combination of drugs. Granisetron and Ondansetron are among the commonly used 5HT3 antagonists and used in combination with dexamethasone for prophylaxis against PONV. The aim of the study was to compare the efficacy of combination of antiemetics-Ondansetron 4mg+Dexamethasone 8mg and Granisetron 1mg+Dexamethasone 8mg in prevention of post operative nausea and vomiting.Methods: 75 patients of ASA 1 and 2 were randomly allocated to three groups-Group 1 (n=25) received Ondansetron 4mg+Dexamethasone 8mg; Group 2 (n=25)-received Granisetron 1mg+Dexamethasone 8mg; Group 3-received saline with dexamethasone 8mg. Standard general anaesthesia protocol was followed. Study drugs were administered at the time of induction. Post operative nausea and vomiting was studied for period of 24hrs. Severity was assessed using PONV Score (0=no nausea;1=nausea only;2=retching;3=vomiting). The adverse effects were also studied.Results: The incidence of PONV was 16% in Group 1 and 2 and 68% in Group 3. The complete response after 24hr period was 32% in control group, 84% in Group 1 and Group 2. Rescue antiemetics were required only in control group. There was no statistical difference noted between Group 1 and Group 2 but there was clinical and statistical significance noted between groups which received prophylactic antiemetic combination and control. Adverse effects were not observed in any group.Conclusions: Granisetron 1mg and Ondansetron 4mg in combination with dexamethasone 8mg are equally effective and safe in decreasing the incidence of post operative nausea and vomiting in laproscopic cholecystectomies under general anaesthesia

Perioperative management of patients with acromegaly-a retrospective analysis

Background: Acromegaly poses several challenges to the anesthetists, neurosurgeons, endocrinologists and intensivists, mandating a careful, coordinated multidisciplinary approach for a successful surgical outcome. An emphasis is required on a thorough preoperative evaluation of airway, neurological and endocrine and metabolic status so as to formulate a suitable perioperative management plan.Methods: The rates of various perioperative complications, both surgical and anesthesia related, during pituitary surgeries in acromegaly patients were studied. Data collected included demographics, patient’s medical history and any associated comorbid conditions, diagnosis, procedure performed, anesthetic management, intraoperative and postoperative complications.Results: This is a retrospective analysis of 22 patients of acromegaly who underwent excision of a growth hormone (GH) secreting pituitary adenoma from October 2012 to December 2017. Male: female, 14:8 with a mean age of 32±9.5 years. The common presenting symptoms were somatic dysmorphism, headache, visual field defects and menstrual irregularities. Preoperative associated co-morbidities were hypertension (4), diabetes mellitus (6), Ischemic Heart Disease (1), hypothyroidism (3), situs solitus (1), lumbar and cervical disc prolapse (1), nephropathy (1) and poliomyelitis (1). One patient had difficult tracheal intubation with repeated attempts at direct laryngoscopy and surgery was deferred to a later date where awake fibreoptic bronchoscopic intubation was done. Two more patients with anticipated difficult airway, trachea was intubated using a fibreoptic bronchoscope. Out of 22 Transsphenoidal surgical approach (transnasal or sublabial) and pterional craniotomy in 18 and 4. Inhalational anaesthetic was used in the majority of patients (isoflurane, 18 and sevoflurane, 03) propofol infusion was used in 1 patient. Intraoperative cardiac complications like hypertension, ventricular ectopics was seen. Postoperatively metabolic, water and electrolyte imbalance were common occurance. CSF rhinorrhoea in 4 patients and one developed meningitis.Conclusions: The present data shows that patients undergoing pituitary surgery for acromegaly have many airway issues, cardiac and metabolic risk factors