THE IMPACT OF SOCIAL MEDIA INFLUENCER’S CREDIBILITY ON THE TRAVEL INTENTIONS OF THE EGYPTIAN MILLENNIALS: APPLIED TO DOMESTIC TOURISM

This study aims to fill the gap in the current influencer marketing literature by analyzing the impact of social media influencers (SMIs) credibility on the domestic travel intentions of Egyptian millennials.An online questionnaire was distributed to a convenience sample of 581 Egyptian millennials to collect primary data. The results indicate that the three dimensions of a SMI’s credibility (trustworthiness, attractiveness, and expertise) have a positive impact on the domestic travel intentions of Egyptian millennials. Moreover, the findings point out that all of SMI’s credibility elements have a significant effect on domestic travel intentions except for SMI’s expertise, which is considered the credibility dimension least affecting the domestic travel intentions of Egyptian millennials.The findings of this study enrich the influencer marketing field in the context of tourism as well as help the destination management organizations (DMOs) and travel agencies select the most persuasive SMIs that can positively influence millennials' travel intentions, specifically in light of the current emphasis on integrating SMIs as one of their marketing techniques

Primate-specific ZNF808 is essential for pancreatic development in humans

Abstract: Identifying genes linked to extreme phenotypes in humans has the potential to highlight biological processes not shared with all other mammals. Here, we report the identification of homozygous loss-of-function variants in the primate-specific gene ZNF808 as a cause of pancreatic agenesis. ZNF808 is a member of the KRAB zinc finger protein family, a large and rapidly evolving group of epigenetic silencers which target transposable elements. We show that loss of ZNF808 in vitro results in aberrant activation of regulatory potential contained in the primate-specific transposable elements it represses during early pancreas development. This leads to inappropriate specification of cell fate with induction of genes associated with liver identity. Our results highlight the essential role of ZNF808 in pancreatic development in humans and the contribution of primate-specific regions of the human genome to congenital developmental disease