Usefulness of a questionnaire for assessing the relationship between eating behavior and steatotic liver disease among Japanese male young adults

Abstract This study aimed to reveal the relationship between eating behavior and nonalcoholic fatty liver disease (NAFLD)/metabolic dysfunction-associated steatotic liver disease (MASLD) in young adults and suggest a questionnaire for eating behavior assessment. We included 322 male graduate students at Gifu University. Diagnoses of NAFLD and MASLD were based on the presence of hepatic steatosis on ultrasonography. Eating behavior was assessed using the eating behavior questionnaire (EBQ) recommended by the Japan Society for the Study of Obesity. We assessed the eating behaviors associated with NAFLD and MASLD using logistic regression, decision tree, and random forest analyses. The median age of the participants was 22 years, and 16% and 11% had NAFLD and MASLD, respectively. The EBQ total score was significantly higher in participants with MASLD than in those without MASLD (102 vs. 90 points, P = 0.006) and in those with NAFLD than in those without NAFLD (97 vs. 90 points, P = 0.007). Among eating behavior categories, the decision tree and random forest analyses revealed that “perception of constitution and weight” was the strongest contributor for NAFLD/MASLD. Our study revealed that eating behavior assessed with the EBQ is robustly associated with NAFLD and MASLD in young male adults

Prevalence of Steatotic Liver Disease Based on a New Nomenclature in the Japanese Population: A Health Checkup-Based Cross-Sectional Study

This cross-sectional study examined the prevalence and characteristics of steatotic liver disease (SLD) based on a recently introduced nomenclature in the Japanese health checkup population. SLD was evaluated using liver ultrasonography, and participants were categorized into metabolic dysfunction-associated steatotic liver disease (MASLD), metabolic dysfunction and alcohol associated steatotic liver disease (MetALD), alcohol-associated/related liver disease (ALD), and cryptogenic SLD groups. The prevalence and characteristics of the SLD subclasses were assessed, and subgroup analyses were conducted for the non-obese (body mass index [BMI] ≤ 25 kg/m2) and lean (BMI ≤ 23 kg/m2) populations. Among the 694 participants, with a median age of 47 years and comprising 54% males, the prevalence of MASLD, MetALD, ALD, and cryptogenic SLD was 26%, 2%, 1%, and 2%, respectively. A remarkable difference was observed in the prevalence of SLD subclasses according to age, sex, and BMI. Subgroup analyses revealed heterogeneous demographic, clinical, and biochemical parameters between the SLD categories. Individuals with MetALD had higher gamma-glutamyl transferase levels, lower platelet counts, and higher fibrosis-4 index than did those with MASLD. Furthermore, the prevalence of non-obese and lean MASLD was 13% and 6%, respectively. This study provides preliminary information on the prevalence of SLD based on a new nomenclature in the Japanese population

Studying the Lunar Ionosphere with SELENE Radio Science Experiment

Radio occultation observations of the electron density near the lunar surface were conducted during the SELENE (Kaguya) mission using the Vstar and Rstar sub-satellites. Previous radio occultation measurements conducted in the Soviet lunar missions have indicated the existence of an ionosphere with peak densities of several hundreds of electrons per cubic centimeters above the dayside lunar surface. These densities are difficult to explain theoretically when the removal of plasma by the solar wind is considered, and thus the generation mechanism of the lunar ionosphere is a major issue, with even the validity of previous observations still under debate. The most serious error source in the measurement is the fluctuation of the terrestrial ionosphere which also exists along the ray path. To cope with this difficulty, about 400 observations were conducted using Vstar to enable statistical analysis of the weak signal of the lunar ionosphere. Another method is to utilize Vstar and Rstar with the second one being used to measure the terrestrial ionosphere contribution. The observations will establish the morphology of the lunar ionosphere and will reveal its relationship with various conditions to provide possible clues to the mechanism