88 research outputs found
1-Year Results of the ZEPHYR Registry (Zilver PTX for the Femoral Artery and Proximal Popliteal Artery) Predictors of Restenosis
AbstractObjectivesThis study sought to assess the rate and predictors of 1-year restenosis after drug-eluting stent implantation for femoropopliteal (FP) lesions in patients with peripheral arterial disease.BackgroundZilver PTX, a paclitaxel-eluting stent for FP lesions, provides superior outcomes to angioplasty and bare-metal stents in clinical trials. However, its real-world outcomes and the associated features remain unclear.MethodsThis was a prospective multicenter study enrolling 831 FP lesions (797 limbs, 690 patients) treated by Zilver PTX implantation. The primary endpoint was 1-year restenosis. Secondary endpoints included major adverse limb event and stent thrombosis.ResultsMean lesion length was 17 ± 10 cm. One-year restenosis, major adverse limb event, and stent thrombosis rates were 37%, 22%, and 2%, respectively. The generalized linear mixed model showed that lesion length ≥16 cm assessed by angiography and distal external elastic membrane area ≤27 mm2 and minimum stent area ≤12 mm2 assessed by intravascular ultrasound were independent risk factors for restenosis. One-year restenosis rates were 15% in cases with none of these risk factors and 50% in those with ≥2 risk factors.ConclusionsThe current study demonstrated 1-year real-world outcomes after drug-eluting stent treatment for FP lesions, including challenging ones in clinical practice. Lesion length, external elastic membrane area, and minimum stent area were independent predictors for restenosis. (Zilver PTX for the Femoral Artery and Proximal Popliteal Artery—Prospective Multicenter Registry [ZEPHYR]; UMIN000008433
TCT-166 Association between leg wound site and prognosis of hemodialysis patients with critical limb ischemia after isolated infrapopliteal balloon angioplasty
COMPARISON OF OSTIAL AND CROSSOVER DRUG-ELUTING STENT IMPLANTATION TECHNIQUE FOR MEDINA (0,1,0) OR (0,0,1) BIFURCATED LESION
Manufacturing Error Conditions Causing Cogging Torque Occurring in Stator in Permanent Magnet Motors
TCT-528 Clinical efficacy of infrapopliteal balloon angioplasty for hemodialysis patients with critical limb ischemia
TCTAP A-065 To Evaluate Clinical Results of Repeat Drug-eluting Stent (DES) Implantation for DES Restenosis at Coronary Artery Lesions with High Degree Hinge Motion
TCTAP A-065 To Evaluate Clinical Results of Repeat Drug-eluting Stent (DES) Implantation for DES Restenosis at Coronary Artery Lesions with High Degree Hinge Motion
- …