13 research outputs found

    Optimization of EHL Lubrication Performance in Thrust Slide-Bearings of Scroll Compressors

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    Previous studies [Refs. 1, 2] revealed the formation of a uniform oil wedge at the periphery of the thrust plate, caused by the elastic deformation of the orbiting thrust plate due to the pressure difference across the orbiting thrust plate, is a significant factor in the high lubrication performance in thrust slide-bearings. In addition to the uniform wedge formation, the high oil film pressure also induces a local elastic deformation of the fixed thrust plate normal to its surface. The normal thrust plate deformation and the oil wedge effectively form an elasto-hydrodynamic-lubrication (EHL) pocket, even more effectively increasing the oil film pressure between the sliding surfaces, due to the envelopment of the oil, as confirmed in our companion paper [3], and an earlier, less-detailed contribution [4]. The present study focuses on aspects of EHL that have both positive and negative effects on the lubrication performance of the thrust slide-bearings in scroll compressors. Theoretical calculations using the average Reynolds equation and Patier-Chen solid contact theory, for the boundary of the local elastic deformation of the thrust slide-bearing, were conducted for a small cooling capacity scroll compressor driven at 3600 rpm with 0.1 kW. An approximate method was developed using characteristic curves to determine the oil film axial force, the average oil film thickness, the frictional force and the frictional coefficient. The calculations considered a variety of pressure differences due to the operation pressure and the thickness of thrust plate. Also cases with a fixed uniform wedge angle at the periphery were calculated. The calculated results suggest a possible maximum reduction in frictional coefficient of about 55% compared to that with a fixed uniform wedge angle. The reduction rate increases with decreasing thrust plate thickness, which, however, restricts the operation pressures to a lower pressure range. Design guidelines for optimizing EHL will be suggested. References: [1] Oku, T., Ishii, N., Anami, K., Knisely, C.W., Sawai, K., Morimoto, T., Hiwata, A. : Theoretical Model of Lubrication Mechanism in the Thrust Slide-Bearing of Scroll Compressors, HVAC&R Research Journal ASHRAE Vol.14, No.2, pp.239-358, 2008-3. [2] Ishii, N., Oku, T., Anami, K., Knisely, C.W., Sawai, K., Morimoto, T., Iida, N. : Experimental Study of the Lubrication Mechanism for Thrust Slide Bearings in Scroll Compressors, HVAC&R Research Journal ASHRAE Vol.14, No.2, 2008-4. [3] Ishii, N., Tsuji, T., Anami, K., Nokiyama, K., Morimoto, T., Sakuda, A., Oku, T., Sawai, K., Knisely, C.W., : “Hydrodynamic-Pressure-Induced Elastic Deformation of Thrust Slide-Bearings in Scroll Compressors and Oil Film Pressure Increase Due to Oil Envelopment,” abstract submitted to 2014 Purdue Herrick Conferences. [4] Ishii, N., Tsuji, T., Oku, T., Anami, K., Knisely, C.W., Nokiyama, K., Morimoto, T., Sakuda, A., Sawai, K. 2012 “Elasto-Hydrodynamic Lubrication Effect in Thrust-Slide Bearings of Scroll Compressors,” 2012 Purdue Conference Paper on (Paper 1438)

    尿中剥離前立腺癌細胞における5-ALA を用いた光力学的診断の有用性

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    BACKGROUND:Past attempts at detecting prostate cancer (PCa) cells in voided urine by traditional cytology have been impeded by undesirably low sensitivities but high specificities. To improve the sensitivities, we evaluate the feasibility and clinical utility of photodynamic diagnosis (PDD) of prostate cancer by using 5-aminolevulinic acid (5-ALA) to examine shed prostate cancer cells in voided urine samples. METHODS:One hundred thirty-eight patients with an abnormal digital rectal exam (DRE) and/or abnormal prostate-specific antigen (PSA) levels were recruited between April 2009 and December 2010. Voided urine specimens were collected before prostate biopsy. Urine specimens were treated with 5-ALA and imaged by fluorescence microscopy and reported as protoporphyrin IX (PPIX) positive (presence of cells demonstrating simultaneous PPIX fluorescence) or PPIX negative (lack of cells demonstrating fluorescence). RESULTS:Of the 138 patients, PCa was detected on needle biopsy in 81 patients (58.7%); of these 81 patients with PCa, 60 were PPIX-positive (sensitivity: 74.1%). Although 57 patients did not harbor PCa by conventional diagnostic procedures, 17 of these at-risk patients were found to be PPIX-positive (specificity: 70.2%). PPIX-PDD was more sensitive compared with DRE and transrectal ultrasound and more specific compared with PSA and PSA density. The incidence of PPIX-PDD positivity did not increase with increasing total PSA levels, tumor stage or Gleason score.CONCLUSIONS:To our knowledge, this is the first successful demonstration of PPIX in urine sediments treated with 5-ALA used to detect PCa in a noninvasive yet highly sensitive manner. However, further studies are warranted to determine the role of PPIX-PPD for PCa detection.博士(医学)・甲第633号・平成27年3月16日© 2014 Nakai et al.; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated
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