Anticancer and Antibacterial Activity of Peganum Harmala and Haloxylon Salicornicum Leaves Extracts

Cancer continues to be a significant risk factor in public health across the globe, responsible for roughly 9.8 million deaths in 2018 (Makena et al., 2018). Some of the most prevalent types of cancer that have been recorded include breast, prostate, leukemia, thyroid, lung, and liver cancer, among others. Antibiotic resistance is also a worldwide concern, not only cancer. This has happened because of microorganisms\u27 expansion, development, and endurance (Davies, 2010). A natural source that has been discovered to have therapeutic medicinal properties against human diseases is Peganum harmala and Haloxylon salicornicum plants. Various concentrations of P. harmala and H. salicornicum were obtained for the purpose of experimenting. The anticancer activity of P. harmala and H. salicornicum was studied using the crystal violet method, the Lipid Peroxidation Assay, and the Caspase 3 Assay techniques. The Kirby-Bauer Disk Diffusion Test was used to determine the antibacterial activity of P. harmala and H. salicornicum against 33 bacterial isolates on various mediums. The findings indicate that P. harmala and H. salicornicum have anticancer potential against the cancer cell lines A549 and PC3. They also have antimicrobial properties. Furthermore, the results demonstrate that the antibiotic action is regulated by the kind of medium used