Cervical traction: a simple step ahead in the prevention of postpartum hemorrhage

Background: Postpartum hemorrhage is the most common preventable cause of maternal mortality in developing countries. The present study aimed to examine the impact of cervical traction technique in reducing the amount of postpartum blood loss and rate of PPH.Methods: This was a case-control, pilot study conducted in a tertiary hospital between June 2017 to June 2018. A total of 200 singletons, low-risk pregnant females, undergoing normal vaginal delivery, were enrolled in this study. Subjects showing a high risk for PPH were excluded. Patients were randomized as case group (n=100) and control group (n=100). The case group received sustained traction for 90 seconds to anterior and posterior lip of the cervix with active management of the third stage of labor, whereas the control group received routine active management of the third stage of labor. All subjects were followed up for 6 hours post-delivery. The amount of blood loss, hematocrit and hemoglobin post-delivery were compared between both groups.Results: The mean blood loss (ml), decrease in hemoglobin (g/L) and decrease in hematocrit post-delivery in cases were significantly low compared to controls (207±37.6 versus 340±49, P<0.01), (0.78±0.2 versus 1.4±0.3, P=0.03) and (1.7±0.2 versus 3.5±0.2, P<0.01). PPH occurred in 7 of 200 (3.5%) patients. The difference in the number of PPH was not significant (5/100; 5% versus 2/100; 2% P=0.2). There were no complications reported due to cervical traction.Conclusions: Cervical traction is a simple and safe maneuver to reduce the amount of postpartum blood loss. Larger RCT is recommended to investigate the reduction in PPH rate

VALIDATED SPECTROPHOTOMETRIC METHOD FOR THE DETERMINATION OF CHLORAMPHENICOL IN PURE AND IN ITS DOSAGE FORM

A simple, précis, rapid sensitive and accurate spectrophotometric methods have been developed for the estimation of Chloramphenicol UV in pure form and its pharmaceutical formulations based on oxidative coupling reaction UV with MBTH reagent at P H-4 which is extractable at 620 nm. Beer's law is obeyed in the concentration range 1-6 ml (10-60 µgml-1). The developed method was applied directly and easily for the analysis of the pharmaceutical formulations. RSD was found to be 0.0194 % and recovery 99.73%. The method was completely validated and proven to be rugged. The interferences of the ingredients and excipients were not observed. The repeatability and the performance of the proved method were established by point and internal hypothesis and through recovery studies.Keywords: Spectrophotometry, Chloramphenicol, MBTH, Oxidative coupling

VALIDATED SPECTROPHOTOMETRIC METHOD FOR THE DETERMINATION OF CHLORAMPHENICOL IN PURE AND IN ITS DOSAGE FORM

Objective: A simple, economic, selective, precise, and accurate UV-Visible spectrophotometric method for the analysis of Chloramphenicol in bulk drug and pharmaceutical formulations was developed and validated in the present study. Methods: Based on oxidative coupling reaction with MBTH reagent at PH-4.5 which is extractable at 620 nm. The Beer's law is obeyed in the concentration range 1-6 ml (10-60 µg ml-1). Results: The RSD was found to be 0.0194% and recovery is 99.73%. The method was completely validated and proven to be rugged. The interferences of the ingredients and recipients were not observed. The repeatability and the performance of the proved method were established by point and internal hypothesis and through recovery studies. Conclusion: The method was found to be accurate and precise, as indicated by recovery studies close to 100 and % RSD is not more than 2. The summery of validation parameters of proposed UV-Visible method is given

Case studies to enhance online student evaluation: Bond University – Surveying students online to improve learning and teaching

One of the most sensible ways of improving learning and teaching is to ask the students for feedback. At the end of each teaching period (i.e. semester or term) all universities and many schools survey their students. Usually these surveys are managed online. Questions ask for student perceptions about teaching, assessment and workload. The survey administrators report four common problems

Finger Ridge Count Correlations Among Four Tribes of Andhra Pradesh, India

The present paper reports the distribution of finger ridge count correlations among four tribal populations from Andhra Pradesh, India viz., Dulia, Kotia, Manne Dora and Manzai Mali, and examines the intra and inter population variation. Higher correlations are recorded in left hands compared to right hands, but they are not significant. The homologous fingers exhibit a stronger correlation. In all the tribes, the correlations between right hand fingers are relatively higher among women when compared to men. Regarding inter population variation Dulia men differ significantly from the men of Manne Dora and the Manzai Mali tribes, and Kotia women also differ from the women of the Manne Dora significantly. The average correlation coefficient of the present populations is similar to other Indian populations reported earlier but lower than African and European populations

Multipaction Susceptibility Margins in Space Travelling wave Tubes

Study of multipaction breakdown margins in the output connector of a travelling-wave tube (TWT) is essential for application in satellite-borne systems. A TWT uses a coaxial ceramic window, a coaxial output coupler and / or a waveguide output coupler that are prone to multipaction breakdown boosted by high RF power due to the ion accumulation in critical regions during the transition of the satellite through plasma pockets in space. A detailed procedure for estimating the multipaction susceptibility margins in a TWT using CST studio and analytical equations is presented in this paper, and output couplers of two typical TWTs are analysed and the results are presented

Chemical composition and antioxidant activity of the crude methanolic extracts of Mentha spicata

The chemical constituents and antioxidant activity of the crude extracts of Mentha spicata were investigated. Phytochemical analysis indicated the presence of sugar, flavonoids and alkaloids in the crude extracts of Mentha spicata. GC-TOFMS (Gas Chromatography Time-of-Flight Mass Spectrometry) analysis indicated the presence of fatty acid methyl esters (hexa decane, hepta decane, octa decane) terpenoids, terpenoid alcohol, caryophyllene and glycosides. Total phenolic components of the crude extracts was found to be 27.26±0.62 mg/g gallic acid equivalent which was determined by Folin-Ciocalteu method. The DPPH (2,2-diphenyl-1-picrylhydrazyl) radical scavenging activity was found to increase with increasing concentrations and  was found to be 54.84±0.57% with an IC50 value of 25.2µg/ml. The reported antioxidant activity may be due to the presence of flavonoids and fatty acid methyl esters which has the scavenging potential by reducing the free radicals. Â